Studies of chemical selectivity of hapten, reactivity, and skin sensitization potency. 3. Synthesis and studies on the reactivity toward model nucleophiles of the 13C-labeled skin sensitizers, 5-chloro-2-methylisothiazol-3-one (MCI) and 2-methylisot

Studies of chemical selectivity of hapten, reactivity, and skin sensitization potency. 3. Synthesis and studies on the reactivity toward model nucleophiles of the 13C-labeled skin sensitizers, 5-chloro-2-methylisothiazol-3-one (MCI) and 2-methylisot

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http://www.wikidata.org/entity/Q44446685
Idiosyncratic adverse drug reactions: current conceptsA critical cysteine residue in monoacylglycerol lipase is targeted by a new class of isothiazolinone-based enzyme inhibitors.A review of the electrophilic reaction chemistry involved in covalent protein binding relevant to toxicity.Penetration and haptenation of p-phenylenediamine.Current knowledge on biomarkers for contact sensitization and allergic contact dermatitis.Effects of 5-chloro-2-methyl-4-isothiazolin-3-one and other candidate biodiesel biocides on rat alveolar macrophages and NR8383 cells.In situ chemical behaviour of methylisothiazolinone (MI) and methylchloroisothiazolinone (MCI) in reconstructed human epidermis: a new approach to the cross-reactivity issue.What determines skin sensitization potency-myths, maybes and realities. Part 1. The 500 molecular weight cut-off.Methylisothiazolinone is categorised as a strong sensitiser in the Murine Local Lymph Node Assay.Recent increase in allergic reactions to methylchloroisothiazolinone/methylisothiazolinone: is methylisothiazolinone the culprit?Effects of a 28-day oral exposure to a 5-chloro-2-methyl-4-isothiazolin-3-one and 2-methyl-4-isothiazolin-3-one biocide formulation in Sprague-Dawley rats.Determination of Protein Haptenation by Chemical Sensitisers within the Complexity of the Human Skin Proteome.Stable isotope labeling method for the investigation of protein haptenation by electrophilic skin sensitizers.
P2860

Studies of chemical selectivity of hapten, reactivity, and skin sensitization potency. 3. Synthesis and studies on the reactivity toward model nucleophiles of the 13C-labeled skin sensitizers, 5-chloro-2-methylisothiazol-3-one (MCI) and 2-methylisot

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http://www.wikidata.org/entity/Q44446685
description
2003 nî lūn-bûn
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2003年の論文
@ja
2003年学术文章
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2003年学术文章
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2003年学术文章
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2003年学术文章
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2003年学术文章
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2003年学术文章
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2003年學術文章
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2003年學術文章
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name
Studies of chemical selectivit ...... l-3-one (MCI) and 2-methylisot
@en
Studies of chemical selectivit ...... l-3-one (MCI) and 2-methylisot
@nl
type
label
Studies of chemical selectivit ...... l-3-one (MCI) and 2-methylisot
@en
Studies of chemical selectivit ...... l-3-one (MCI) and 2-methylisot
@nl
prefLabel
Studies of chemical selectivit ...... l-3-one (MCI) and 2-methylisot
@en
Studies of chemical selectivit ...... l-3-one (MCI) and 2-methylisot
@nl
P1433
P1476
P2093
P304
P31
P356
P433
P478
P577
P698
P356
P1433
P1476
Studies of chemical selectivit ...... l-3-one (MCI) and 2-methylisot
@en
P2093
P304
P31
P356
P433
P478
P577
P698