Measurement of the millisecond activation switch of G protein-coupled receptors in living cells.
about
GPCR oligomers in pharmacology and signalingStructure and function of an irreversible agonist-β(2) adrenoceptor complexIdentification of two distinct inactive conformations of the beta2-adrenergic receptor reconciles structural and biochemical observationsFunction and Regulation of Heterotrimeric G Proteins during ChemotaxisFluorescent approaches for understanding interactions of ligands with G protein coupled receptorsKir3 channel signaling complexes: focus on opioid receptor signalingSingle-cell analysis of G-protein signal transductionGaussian Accelerated Molecular Dynamics: Unconstrained Enhanced Sampling and Free Energy CalculationCommunication over the network of binary switches regulates the activation of A2A adenosine receptorPersistent cAMP-signals triggered by internalized G-protein-coupled receptorsPolarization of migrating monocytic cells is independent of PI 3-kinase activityDimeric Arrangement of the Parathyroid Hormone Receptor and a Structural Mechanism for Ligand-induced DissociationTransmembrane signal transduction by peptide hormones via family B G protein-coupled receptorsRole of DARPP-32 and ARPP-21 in the Emergence of Temporal Constraints on Striatal Calcium and Dopamine IntegrationActivation biosensor for G protein-coupled receptors: a FRET-based m1 muscarinic activation sensor that regulates G(q)Mechanosensory Signaling in Enterochromaffin Cells and 5-HT Release: Potential Implications for Gut InflammationActivation of G protein-coupled receptors: beyond two-state models and tertiary conformational changes.Ways and means of coping with uncertainties of the relationship of the genetic blue print to protein structure and function in the cellFörster resonance energy transfer as a tool to study photoreceptor biologyReal-time optical recording of beta1-adrenergic receptor activation reveals supersensitivity of the Arg389 variant to carvedilolPathway and mechanism of drug binding to G-protein-coupled receptors.Structural heterogeneity of the μ-opioid receptor's conformational ensemble in the apo stateRhodopsin photointermediates in two-dimensional crystals at physiological temperatures.Luciferase activity under direct ligand-dependent control of a muscarinic acetylcholine receptor.Mapping of allosteric druggable sites in activation-associated conformers of the M2 muscarinic receptorKinetics of M1 muscarinic receptor and G protein signaling to phospholipase C in living cellsPutting G protein-coupled receptor-mediated activation of phospholipase C in the limelightGPCR and G proteins: drug efficacy and activation in live cells.Ligand-induced rearrangements of the GABA(B) receptor revealed by fluorescence resonance energy transfer.Seven transmembrane receptors as shapeshifting proteins: the impact of allosteric modulation and functional selectivity on new drug discovery.Teaching old receptors new tricks: biasing seven-transmembrane receptors.Ligand-dependent activation and deactivation of the human adenosine A(2A) receptor.Turn-on switch in parathyroid hormone receptor by a two-step parathyroid hormone binding mechanism.FRET-based detection of M1 muscarinic acetylcholine receptor activation by orthosteric and allosteric agonists.Identifying functionally important conformational changes in proteins: activation of the yeast α-factor receptor Ste2pDetecting rearrangements of shaker and NaChBac in real-time with fluorescence spectroscopy in patch-clamped mammalian cells.Structural insights into human GPCR protein OA1: a computational perspective.The allosteric vestibule of a seven transmembrane helical receptor controls G-protein couplingDual signaling is differentially activated by different active states of the metabotropic glutamate receptor 1alphaMonitoring the formation of dynamic G-protein-coupled receptor-protein complexes in living cells.
P2860
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P2860
Measurement of the millisecond activation switch of G protein-coupled receptors in living cells.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年学术文章
@wuu
2003年学术文章
@zh-cn
2003年学术文章
@zh-hans
2003年学术文章
@zh-my
2003年学术文章
@zh-sg
2003年學術文章
@yue
2003年學術文章
@zh
2003年學術文章
@zh-hant
name
Measurement of the millisecond ...... led receptors in living cells.
@en
Measurement of the millisecond ...... led receptors in living cells.
@nl
type
label
Measurement of the millisecond ...... led receptors in living cells.
@en
Measurement of the millisecond ...... led receptors in living cells.
@nl
prefLabel
Measurement of the millisecond ...... led receptors in living cells.
@en
Measurement of the millisecond ...... led receptors in living cells.
@nl
P2093
P356
P1433
P1476
Measurement of the millisecond ...... led receptors in living cells.
@en
P2093
Cornelius Krasel
Mariàn Castro
Moritz Bünemann
P2888
P304
P356
10.1038/NBT838
P577
2003-06-15T00:00:00Z