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Soluble epoxide hydrolase deficiency alters pancreatic islet size and improves glucose homeostasis in a model of insulin resistanceLoss of Myt1 function partially compromises endocrine islet cell differentiation and pancreatic physiological function in the mouseAngiopoietin 2 alters pancreatic vascularization in diabetic conditionsCurrent status of immunomodulatory and cellular therapies in preclinical and clinical islet transplantation.T-cadherin (Cdh13) in association with pancreatic β-cell granules contributes to second phase insulin secretionVEGF-A recruits a proangiogenic MMP-9-delivering neutrophil subset that induces angiogenesis in transplanted hypoxic tissueThe diabetes-susceptible gene SLC30A8/ZnT8 regulates hepatic insulin clearanceVascular endothelial growth factor coordinates islet innervation via vascular scaffolding.Insulin secretion from beta cells in intact mouse islets is targeted towards the vasculature.The biomechanical properties of an epithelial tissue determine the location of its vasculatureImpairment of rat fetal beta-cell development by maternal exposure to dexamethasone during different time-windows.Is dynamic autocrine insulin signaling possible? A mathematical model predicts picomolar concentrations of extracellular monomeric insulin within human pancreatic islets.Islet microenvironment, modulated by vascular endothelial growth factor-A signaling, promotes β cell regeneration.Matrix metalloproteinases, T cell homing and beta-cell mass in type 1 diabetes.Anchoring of vascular endothelial growth factor to surface-immobilized heparin on pancreatic islets: implications for stimulating islet angiogenesisConsumption of a Western-style diet during pregnancy impairs offspring islet vascularization in a Japanese macaque model.Glucose intolerance and impaired insulin secretion in pancreas-specific signal transducer and activator of transcription-3 knockout mice are associated with microvascular alterations in the pancreas.The central role of antigen presentation in islets of Langerhans in autoimmune diabetesPancreas-specific Gsalpha deficiency has divergent effects on pancreatic alpha- and beta-cell proliferationThe ghrelin gene products and exendin-4 promote survival of human pancreatic islet endothelial cells in hyperglycaemic conditions, through phosphoinositide 3-kinase/Akt, extracellular signal-related kinase (ERK)1/2 and cAMP/protein kinase A (PKA) siFoxO1 gain of function in the pancreas causes glucose intolerance, polycystic pancreas, and islet hypervascularization.Engineered vascular beds provide key signals to pancreatic hormone-producing cells.Erythropoietin protects against diabetes through direct effects on pancreatic beta cellsSustained beta-cell dysfunction but normalized islet mass in aged thrombospondin-1 deficient mice.Critical roles for macrophages in islet angiogenesis and maintenance during pancreatic degenerationNapoleone Ferrara and the saga of vascular endothelial growth factor.Altered islet morphology but normal islet secretory function in vitro in a mouse model with microvascular alterations in the pancreasPlacental insufficiency decreases pancreatic vascularity and disrupts hepatocyte growth factor signaling in the pancreatic islet endothelial cell in fetal sheepVascular endothelial growth factor localization in the adult.Pancreatic duct cells as a source of VEGF in mice.Inhibition of vascular endothelial growth factor (VEGF) signaling in cancer causes loss of endothelial fenestrations, regression of tumor vessels, and appearance of basement membrane ghosts.Pleiotropic and age-dependent effects of decreased protein modification by O-linked N-acetylglucosamine on pancreatic β-cell function and vascularization.A low-oxygenated subpopulation of pancreatic islets constitutes a functional reserve of endocrine cells.An in vitro assay reveals a role for the diaphragm protein PV-1 in endothelial fenestra morphogenesisIsolation, characterization and potential role in beta cell-endothelium cross-talk of extracellular vesicles released from human pancreatic isletsLoss of PDGF-B activity increases hepatic vascular permeability and enhances insulin sensitivity.Connective tissue growth factor modulates adult β-cell maturity and proliferation to promote β-cell regeneration in miceG protein-coupled receptor signaling and sphingosine-1-phosphate play a phylogenetically conserved role in endocrine pancreas morphogenesisClinical islet transplant: current and future directions towards tolerance.Clinical development of VEGF signaling pathway inhibitors in childhood solid tumors.
P2860
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P2860
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年学术文章
@wuu
2003年学术文章
@zh-cn
2003年学术文章
@zh-hans
2003年学术文章
@zh-my
2003年学术文章
@zh-sg
2003年學術文章
@yue
2003年學術文章
@zh
2003年學術文章
@zh-hant
name
Role of VEGF-A in vascularization of pancreatic islets.
@en
Role of VEGF-A in vascularization of pancreatic islets.
@nl
type
label
Role of VEGF-A in vascularization of pancreatic islets.
@en
Role of VEGF-A in vascularization of pancreatic islets.
@nl
prefLabel
Role of VEGF-A in vascularization of pancreatic islets.
@en
Role of VEGF-A in vascularization of pancreatic islets.
@nl
P2093
P1433
P1476
Role of VEGF-A in vascularization of pancreatic islets.
@en
P2093
Dennis Brown
Douglas A Melton
Eckhard Lammert
Guqiang Gu
Hans Peter Gerber
Lewis Charles Murtaugh
Margaret McLaughlin
Napoleone Ferrara
Rolf Brekken
P304
P356
10.1016/S0960-9822(03)00378-6
P407
P577
2003-06-01T00:00:00Z