Alpha-lipoic acid preconditioning reduces ischemia-reperfusion injury of the rat liver via the PI3-kinase/Akt pathway. - Wikidata - awgldk - TriplyDB

Alpha-lipoic acid preconditioning reduces ischemia-reperfusion injury of the rat liver via the PI3-kinase/Akt pathway.

Alpha-lipoic acid preconditioning reduces ischemia-reperfusion injury of the rat liver via the PI3-kinase/Akt pathway.

http://www.wikidata.org/entity/Q44484435

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Akt: A Therapeutic Target in Hepatic Ischemia-Reperfusion Injury.α-Lipoic acid reduces infarct size and preserves cardiac function in rat myocardial ischemia/reperfusion injury through activation of PI3K/Akt/Nrf2 pathway.Non-receptor tyrosine kinase Src is required for ischemia-stimulated neuronal cell proliferation via Raf/ERK/CREB activation in the dentate gyrus.Protective effects of pretreatment with oleanolic acid in rats in the acute phase of hepatic ischemia-reperfusion injury: role of the PI3K/Akt pathway.Reduction of ischemia reperfusion injury after liver resection and hepatic inflow occlusion by alpha-lipoic acid in humans.PI 3-kinase pathway is responsible for antiapoptotic effects of atrial natriuretic peptide in rat liver transplantation High-mobility group box-1 induces proinflammatory cytokines production of Kupffer cells through TLRs-dependent signaling pathway after burn injury Protective effects of ischemic preconditioning and application of lipoic acid prior to 90 min of hepatic ischemia in a rat model CXC chemokine ligand 12 protects pancreatic β-cells from necrosis through Akt kinase-mediated modulation of poly(ADP-ribose) polymerase-1 activity.Alpha-lipoic acid attenuates LPS-induced inflammatory responses by activating the phosphoinositide 3-kinase/Akt signaling pathway Protein kinase B/Akt modulates nephrotoxicant-induced necrosis in renal cells.The role of AKT1 and autophagy in the protective effect of hydrogen sulphide against hepatic ischemia/reperfusion injury in mice The contemporary role of antioxidant therapy in attenuating liver ischemia-reperfusion injury: a review.Molecular Mechanisms of Lipoic Acid Protection against Aflatoxin B₁-Induced Liver Oxidative Damage and Inflammatory Responses in Broilers Dietary Supplementation of Vitamin E and α-Lipoic Acid Upregulates Cell Growth and Signaling Genes in Rat Myocardium Akt in ischemia and reperfusion.Role of reactive metabolites of oxygen and nitrogen in partial liver transplantation: lessons learned from reduced-size liver ischaemia and reperfusion injury.Akt activation improves oxidative phosphorylation in renal proximal tubular cells following nephrotoxicant injury Protein kinases in organ ischemia and reperfusion.Preactivation of NKT cells with alpha-GalCer protects against hepatic ischemia-reperfusion injury in mouse by a mechanism involving IL-13 and adenosine A2A receptor Current status of oxidative stress in pediatric liver transplantation.Nitric oxide and redox regulation in the liver: part II. Redox biology in pathologic hepatocytes and implications for intervention.Lipoic acid: energy metabolism and redox regulation of transcription and cell signaling Current knowledge on oxidative stress in hepatic ischemia/reperfusion.Potential role of Akt signaling in chronic kidney disease.alpha-lipoic acid inhibits endotoxin-stimulated expression of iNOS and nitric oxide independent of the heat shock response in RAW 264.7 cells.Effects of remifentanil on hemodynamics, liver function and ICAM-1 expression in liver cancer patients undergoing surgery.Effects of alpha-lipoic acid on endothelial function in aged diabetic and high-fat fed rats.Autophagy and liver ischemia-reperfusion injury.Antioxidants prevent ethanol-associated apoptosis in fetal rhombencephalic neurons.Dose-related cytoprotective effect of alpha-lipoic acid on hydrogen peroxide-induced oxidative stress to pancreatic beta cells.Molecular hepatoprotective effects of lipoic acid against carbon tetrachloride-induced liver fibrosis in rats: Hepatoprotection at molecular level.Tyrosine phosphorylation of insulin receptor substrates during ischemia/reperfusion-induced apoptosis in rat liver.Evidence for a non-antioxidant, dose-dependent role of alpha -lipoic acid in caspase-3 and ERK2 activation in endothelial cells.Preincubation of rat and human hepatocytes with cytoprotectants prior to cryopreservation can improve viability and function upon thawing.Peroxisome proliferator-activated receptor-gamma protects against hepatic ischemia/reperfusion injury in mice.Preincubation of rat and human hepatocytes with cytoprotectants prior to cryopreservation can improve viability and function upon thawing.Effects of wortmannin on phosphorylation of PDK1, GSK3-beta, PTEN and expression of Skp2 mRNA after ischemia/reperfusion injury in the mouse kidney.Alpha Lipoic Acid: A Therapeutic Strategy that Tend to Limit the Action of Free Radicals in Transplantation.CMX-2043 Efficacy in a Rat Model of Cardiac Ischemia-Reperfusion Injury.

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P2860

Alpha-lipoic acid preconditioning reduces ischemia-reperfusion injury of the rat liver via the PI3-kinase/Akt pathway.

http://www.wikidata.org/entity/Q44484435

description

2003 nî lūn-bûn

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2003年の論文

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2003年学术文章

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2003年学术文章

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2003年学术文章

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2003年学术文章

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2003年学术文章

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2003年學術文章

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2003年學術文章

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2003年學術文章

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name

Alpha-lipoic acid precondition ...... ia the PI3-kinase/Akt pathway.

@en

Alpha-lipoic acid precondition ...... ia the PI3-kinase/Akt pathway.

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type

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Alpha-lipoic acid precondition ...... ia the PI3-kinase/Akt pathway.

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Alpha-lipoic acid precondition ...... ia the PI3-kinase/Akt pathway.

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Alpha-lipoic acid precondition ...... ia the PI3-kinase/Akt pathway.

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Alpha-lipoic acid precondition ...... ia the PI3-kinase/Akt pathway.

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American Journal of Physiology - Gastrointestinal and Liver Physiology

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Alpha-lipoic acid precondition ...... ia the PI3-kinase/Akt pathway.

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Alexandra K Kiemer

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Angelika M Vollmar

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Christian Müller

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Elke Koch

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Friedrich Dünschede

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P2860

AKT/PKB and other D3 phosphoinositide-regulated kinases: kinase activation by phosphoinositide-dependent phosphorylation

Ischemic preconditioning activates phosphatidylinositol-3-kinase upstream of protein kinase C

Cellular survival: a play in three Akts

Mechanism of cell death during warm hepatic ischemia-reperfusion in rats: apoptosis or necrosis?

Therapeutic approaches for ischemia/reperfusion injury in the liver.

Preservation injury of the liver: mechanisms and novel therapeutic strategies.

Alcoholic fatty liver differentially induces a neutrophil-chemokine and hepatic necrosis after ischemia-reperfusion in rat.

Alpha-lipoic acid in liver metabolism and disease.

Depletion of hepatic glutathione prevents death receptor-dependent apoptotic and necrotic liver injury in mice

Reactive oxygen species during ischemia-reflow injury in isolated perfused rat liver

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4

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285

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reperfusion injury