N-aryl-2,6-dimethylbenzamides, a new generation of tocainide analogues as blockers of skeletal muscle voltage-gated sodium channels.
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Therapeutic Approaches to Genetic Ion Channelopathies and Perspectives in Drug DiscoveryStereoselective Modulation of P-Glycoprotein by Chiral Small Molecules.Increased sodium channel use-dependent inhibition by a new potent analogue of tocainide greatly enhances in vivo antimyotonic activity.Toward precision medicine in myotonic syndromes.Dual Action of Mexiletine and Its Pyrroline Derivatives as Skeletal Muscle Sodium Channel Blockers and Anti-oxidant Compounds: Toward Novel Therapeutic Potential.Ligand efficiency metrics in drug discovery: the pros and cons from a practical perspective.
P2860
N-aryl-2,6-dimethylbenzamides, a new generation of tocainide analogues as blockers of skeletal muscle voltage-gated sodium channels.
description
2014 nî lūn-bûn
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2014年の論文
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2014年学术文章
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2014年学术文章
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2014年学术文章
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2014年学术文章
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2014年学术文章
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2014年學術文章
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name
N-aryl-2,6-dimethylbenzamides, ...... voltage-gated sodium channels.
@en
N-aryl-2,6-dimethylbenzamides, ...... voltage-gated sodium channels.
@nl
type
label
N-aryl-2,6-dimethylbenzamides, ...... voltage-gated sodium channels.
@en
N-aryl-2,6-dimethylbenzamides, ...... voltage-gated sodium channels.
@nl
prefLabel
N-aryl-2,6-dimethylbenzamides, ...... voltage-gated sodium channels.
@en
N-aryl-2,6-dimethylbenzamides, ...... voltage-gated sodium channels.
@nl
P2093
P50
P356
P1476
N-aryl-2,6-dimethylbenzamides, ...... voltage-gated sodium channels.
@en
P2093
Carlo Bertucci
Cecilia Fortugno
Jean-François Desaphy
Marilena Muraglia
P304
P356
10.1021/JM401864B
P407
P50
P577
2014-03-07T00:00:00Z