Decreased expression of genes involved in sulfur amino acid metabolism in frataxin-deficient cells.
about
A pool of extramitochondrial frataxin that promotes cell survivalSplice mutation in the iron-sulfur cluster scaffold protein ISCU causes myopathy with exercise intoleranceFriedreich's Ataxia: A Neuronal Point of View on the Oxidative Stress HypothesisUnderstanding the binding properties of an unusual metal-binding protein--a study of bacterial frataxinThe first cellular models based on frataxin missense mutations that reproduce spontaneously the defects associated with Friedreich ataxiaGeneration and characterisation of Friedreich ataxia YG8R mouse fibroblast and neural stem cell modelsFrataxin is essential for extramitochondrial Fe-S cluster proteins in mammalian tissuesDyclonine rescues frataxin deficiency in animal models and buccal cells of patients with Friedreich's ataxia.Autosomal recessive cerebellar ataxias.Rhodanese-thioredoxin system and allyl sulfur compounds.Friedreich's ataxia, no changes in mitochondrial labile iron in human lymphoblasts and fibroblasts: a decrease in antioxidative capacity?Visual system involvement in patients with Friedreich's ataxia.Limitations in a frataxin knockdown cell model for Friedreich ataxia in a high-throughput drug screenAltered gene expression and DNA damage in peripheral blood cells from Friedreich's ataxia patients: cellular model of pathology.PGC-1alpha down-regulation affects the antioxidant response in Friedreich's ataxia.Gene expression profiling in frataxin deficient mice: microarray evidence for significant expression changes without detectable neurodegenerationFriedreich ataxia: molecular mechanisms, redox considerations, and therapeutic opportunities.The neuro-ophthalmology of mitochondrial diseaseFrataxin deficiency increases cyclooxygenase 2 and prostaglandins in cell and animal models of Friedreich's ataxia.Frataxin, iron-sulfur clusters, heme, ROS, and aging.HSC20 interacts with frataxin and is involved in iron-sulfur cluster biogenesis and iron homeostasis.Pathways to motor incoordination: the inherited ataxias.A gene expression phenotype in lymphocytes from Friedreich ataxia patients.Long intronic GAA*TTC repeats induce epigenetic changes and reporter gene silencing in a molecular model of Friedreich ataxia.Exploring frataxin function.Research on plants for the understanding of diseases of nuclear and mitochondrial origin.Frataxin overexpressing mice.Frataxin deficiency induces Schwann cell inflammation and death.Frataxin knockdown causes loss of cytoplasmic iron-sulfur cluster functions, redox alterations and induction of heme transcripts.Frataxin deficiency leads to defects in expression of antioxidants and Nrf2 expression in dorsal root ganglia of the Friedreich's ataxia YG8R mouse modelManganese is the link between frataxin and iron-sulfur deficiency in the yeast model of Friedreich ataxia.Comprehensive analysis of gene expression patterns in Friedreich's ataxia fibroblasts by RNA sequencing reveals altered levels of protein synthesis factors and solute carriers.Gene Expression Profile in Peripheral Blood Cells of Friedreich Ataxia Patients.Erythropoietin in Friedreich ataxia: No effect on frataxin in a randomized controlled trial
P2860
Q24316486-4BA9E48D-4927-4193-96D3-769B3AC2529DQ24656037-D149FA08-FB3F-46DF-B3AE-3837498AABDAQ26830073-5978284B-9004-4ED3-A017-9022A5A58A78Q27646861-5B8AF985-9EC4-4F37-BB6C-E8F509640CF0Q28475804-E0E39E32-C368-4EDE-B862-8CAC95B0CDFCQ28540063-6826781D-07B6-4242-B0CA-5F8F80B743E6Q28586434-207DB4FE-E440-4389-BA5B-468146F548E9Q30602174-3503DC88-8D45-41EC-AD57-A16F2DB12C51Q31078351-3E2E34CE-84E5-4A7A-BC9A-F2F6229A9D7DQ31162170-6C63F1B4-29FC-4FA4-8FB3-78D871C621D0Q33210293-E760E53A-27A0-4C54-9039-EDFB90D817EFQ33377900-3D2C3CD8-3069-418A-A329-F790C2C19F1BQ33496330-4A905181-600C-422D-8B6B-ECEF7A555087Q33525513-83DA764D-45DD-41B7-BFBC-403032B626EBQ33552305-CE1BE12F-5AD8-4395-9015-3336E066BA57Q33914816-299FEB2D-B1BB-45D0-A645-0BB6629FD214Q34076650-D9A2F6EA-0216-47F3-9F60-286FAA022F25Q34338783-11FF2BAF-D494-428A-B32B-7F08CECD9AADQ34575719-0A6D6166-59A7-4C8B-A166-3A5947585817Q35650906-4A1D9598-5A30-4CAD-BD46-01FAE8AFAFD8Q35817466-43477F51-F8F0-471D-8F40-73C9016ABD18Q35841041-E3A0BB1D-48AA-4A96-BFE2-8CF064CBB1E1Q36822492-207DDFA1-0949-4290-842C-60D6A2B54631Q36959663-B5A9F633-30AD-45C7-8876-F8E2854C3994Q37957815-7DE7572C-D4DC-4E1E-B3BC-EFF89243363FQ38018051-48549853-452E-4467-B777-80890A4F9720Q38337923-2AE879E9-F65B-414C-9463-3B4971626A6CQ39813005-E032E1AE-452F-4E1E-A8E1-3EE623D1A5C0Q40209576-39866E68-5B39-4284-8819-21287270DD81Q42678097-18E3876A-9140-42B6-8869-C319087A0745Q46970707-9154C1E3-CCA3-4C9C-8B86-28D03A071FCDQ47104232-6C1270E0-689E-4EF5-97AA-5D4FD4D0BD12Q52931377-97ACDE32-0837-4BB8-B3D7-C817A36999CAQ58451539-980FA650-00F1-49B5-9E5C-0DA60427F7A4
P2860
Decreased expression of genes involved in sulfur amino acid metabolism in frataxin-deficient cells.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年学术文章
@wuu
2003年学术文章
@zh
2003年学术文章
@zh-cn
2003年学术文章
@zh-hans
2003年学术文章
@zh-my
2003年学术文章
@zh-sg
2003年學術文章
@yue
2003年學術文章
@zh-hant
name
Decreased expression of genes ...... m in frataxin-deficient cells.
@en
Decreased expression of genes ...... m in frataxin-deficient cells.
@nl
type
label
Decreased expression of genes ...... m in frataxin-deficient cells.
@en
Decreased expression of genes ...... m in frataxin-deficient cells.
@nl
prefLabel
Decreased expression of genes ...... m in frataxin-deficient cells.
@en
Decreased expression of genes ...... m in frataxin-deficient cells.
@nl
P2093
P356
P1476
Decreased expression of genes ...... sm in frataxin-deficient cells
@en
P2093
Eleonora Napoli
Gino Cortopassi
Guolin Tan
P304
P356
10.1093/HMG/DDG187
P50
P577
2003-07-01T00:00:00Z