Administration of the p38 MAPK inhibitor SB203580 affords brain protection with a wide therapeutic window against focal ischemic insult.
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Adenosine A2A receptors modulate acute injury and neuroinflammation in brain ischemiaBlood-brain barrier integrity and glial support: mechanisms that can be targeted for novel therapeutic approaches in strokeRole of P38 MAPK on MMP Activity in Photothrombotic Stroke Mice as Measured using an Ultrafast MMP Activatable Probe.MKK3 was involved in larval settlement of the barnacle Amphibalanus amphitrite through activating the kinase activity of p38MAPKPropofol attenuates oxidative stress-induced PC12 cell injury via p38 MAP kinase dependent pathway.Ethyl pyruvate protects against hypoxic-ischemic brain injury via anti-cell death and anti-inflammatory mechanisms.Targeting protein kinases in central nervous system disordersEvidence that adiponectin receptor 1 activation exacerbates ischemic neuronal deathNeuroprotective effects of bilobalide on cerebral ischemia and reperfusion injury are associated with inhibition of pro-inflammatory mediator production and down-regulation of JNK1/2 and p38 MAPK activation.The p38alpha mitogen-activated protein kinase limits the CNS proinflammatory cytokine response to systemic lipopolysaccharide, potentially through an IL-10 dependent mechanismPaeoniflorin protects against ischemia-induced brain damages in rats via inhibiting MAPKs/NF-κB-mediated inflammatory responses.p38α (MAPK14) critically regulates the immunological response and the production of specific cytokines and chemokines in astrocytes.Protective effect of glycyrrhizin, a direct HMGB1 inhibitor, on focal cerebral ischemia/reperfusion-induced inflammation, oxidative stress, and apoptosis in ratsNovel Therapeutic Targets in Neuroinflammation and Neuropathic PainMinocycline ameliorates LPS-induced inflammation in human monocytes by novel mechanisms including LOX-1, Nur77 and LITAF inhibition.Involvement of mitogen-activated protein kinase pathways in expression of the water channel protein aquaporin-4 after ischemia in rat cortical astrocytes.Minocycline as a neuroprotective agent.Neuroprotective effect of STAZN, a novel azulenyl nitrone antioxidant, in focal cerebral ischemia in rats: dose-response and therapeutic window.Ras family small GTPase-mediated neuroprotective signaling in stroke.Microglia in cerebral ischemia: molecular actions and interactions.Modulation of inflammatory cytokines and mitogen-activated protein kinases by acetate in primary astrocytes.Prevention of JNK phosphorylation as a mechanism for rosiglitazone in neuroprotection after transient cerebral ischemia: activation of dual specificity phosphatase.Calcitonin gene-related peptide protects rats from cerebral ischemia/reperfusion injury via a mechanism of action in the MAPK pathwayA re-assessment of minocycline as a neuroprotective agent in a rat spinal cord contusion model.Protein kinases in organ ischemia and reperfusion.Selective suppression of the α isoform of p38 MAPK rescues late-stage tau pathology.Cell biology of ischemia/reperfusion injury.2-Chloroethanol Induced Upregulation of Matrix Metalloproteinase-2 in Primary Cultured Rat Astrocytes Via MAPK Signal Pathways.Increased Apoptosis in the Paraventricular Nucleus Mediated by AT1R/Ras/ERK1/2 Signaling Results in Sympathetic Hyperactivity and Renovascular Hypertension in Rats after Kidney Injury.Involvement of p38 MAPK in reactive astrogliosis induced by ischemic stroke.New advances on glial activation in health and disease.Regulation of mitophagy in ischemic brain injury.The Mitogen-Activated Protein Kinase (MAPK) Signaling Pathway as a Discovery Target in Stroke.MicroRNA-128-3p Protects Mouse Against Cerebral Ischemia Through Reducing p38α Mitogen-Activated Protein Kinase Activity.Evidence that NF-κB and MAPK Signaling Promotes NLRP Inflammasome Activation in Neurons Following Ischemic Stroke.Rapid Disruption of Cellular Integrity of Zinc-treated Astroglia Is Regulated by p38 MAPK and Ca-dependent Mechanisms.Ischemia/Reperfusion.Potassium 2-(1-hydroxypentyl)-benzoate attenuates neuronal apoptosis in neuron-astrocyte co-culture system through neurotrophy and neuroinflammation pathway.Increased p38 mitogen-activated protein kinase signaling is involved in the oxidative stress associated with oxygen and glucose deprivation in neonatal hippocampal slice cultures.Early steps of microglial activation are directly affected by neuroprotectant FK506 in both in vitro inflammation and in rat model of stroke.
P2860
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P2860
Administration of the p38 MAPK inhibitor SB203580 affords brain protection with a wide therapeutic window against focal ischemic insult.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年学术文章
@wuu
2003年学术文章
@zh
2003年学术文章
@zh-cn
2003年学术文章
@zh-hans
2003年学术文章
@zh-my
2003年学术文章
@zh-sg
2003年學術文章
@yue
2003年學術文章
@zh-hant
name
Administration of the p38 MAPK ...... against focal ischemic insult.
@en
Administration of the p38 MAPK ...... against focal ischemic insult.
@nl
type
label
Administration of the p38 MAPK ...... against focal ischemic insult.
@en
Administration of the p38 MAPK ...... against focal ischemic insult.
@nl
prefLabel
Administration of the p38 MAPK ...... against focal ischemic insult.
@en
Administration of the p38 MAPK ...... against focal ischemic insult.
@nl
P2093
P356
P1476
Administration of the p38 MAPK ...... against focal ischemic insult.
@en
P2093
Chun Shu Piao
Ja-Kyeong Lee
Jung-Bin Kim
P304
P356
10.1002/JNR.10671
P577
2003-08-01T00:00:00Z