Necrotic but not apoptotic cell death releases heat shock proteins, which deliver a partial maturation signal to dendritic cells and activate the NF-kappa B pathway.
about
The danger theory: 20 years laterHeat shock proteins as danger signals for cancer detectionLipopolysaccharide-free heat shock protein 60 activates T cellsTherapeutic cancer vaccines: using unique antigensResolution-associated molecular patterns (RAMP): RAMParts defending immunological homeostasis?Mechanism of dichotomy between CD8+ responses elicited by apoptotic and necrotic cellsCD24-Siglec G/10 discriminates danger- from pathogen-associated molecular patternsMacrophages promote axon regeneration with concurrent neurotoxicityFever therapy revisitedC1q and mannose binding lectin engagement of cell surface calreticulin and CD91 initiates macropinocytosis and uptake of apoptotic cellsProteomics profiling of chikungunya-infected Aedes albopictus C6/36 cells reveal important mosquito cell factors in virus replicationInterleukin-1 stimulates beta-cell necrosis and release of the immunological adjuvant HMGB1Extracellular Release and Signaling by Heat Shock Protein 27: Role in Modifying Vascular InflammationSpatiotemporal Regulation of Hsp90-Ligand Complex Leads to Immune ActivationPrognostic and Predictive Value of DAMPs and DAMP-Associated Processes in CancerHeat shock proteins: stimulators of innate and acquired immunityVaccine therapies in malignant gliomaFunctions of heat shock proteins in pathways of the innate and adaptive immune systemExtracellular Hsp90 (eHsp90) as the actual target in clinical trials: intentionally or unintentionallyRadiation as immunomodulator: implications for dendritic cell-based immunotherapyAntitumor immune responses mediated by dendritic cells: How signals derived from dying cancer cells drive antigen cross-presentationThe Endoplasmic Reticulum Chaperone GRP170: From Immunobiology to Cancer TherapeuticsInteraction between Cannabinoid System and Toll-Like Receptors Controls InflammationThe human HSP70 family of chaperones: where do we stand?Host type I IFN signals are required for antitumor CD8+ T cell responses through CD8{alpha}+ dendritic cellsMicroRNA29a regulates IL-33-mediated tissue remodelling in tendon diseasePrimary sterile necrotic cells fail to cross-prime CD8(+) T cellsThe dendritic cell response to classic, emerging, and homeostatic danger signals. Implications for autoimmunityFunctional annotation of proteomic data from chicken heterophils and macrophages induced by carbon nanotube exposureIdentification of gp96 as a novel target for treatment of autoimmune disease in miceOxidative stress induces monocyte necrosis with enrichment of cell-bound albumin and overexpression of endoplasmic reticulum and mitochondrial chaperonesIncrease in periosteal angiogenesis through heat shock conditioningAnti-inflammatory effects of the 70 kDa heat shock protein in experimental strokeTotal parenteral-nutrition-mediated dendritic-cell activation and infiltration into the small intestine in a rat modelIntracellular interleukin-1 receptor 2 binding prevents cleavage and activity of interleukin-1α, controlling necrosis-induced sterile inflammationHow dying cells alert the immune system to dangerSterile inflammation: sensing and reacting to damageLow-Intensity Focused Ultrasound Induces Reversal of Tumor-Induced T Cell Tolerance and Prevents Immune Escape.Release of endogenous danger signals from HIFU-treated tumor cells and their stimulatory effects on APCs.Mutations in the substrate binding site of human heat-shock protein 70 indicate specific interaction with HLA-DR outside the peptide binding groove.
P2860
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P2860
Necrotic but not apoptotic cell death releases heat shock proteins, which deliver a partial maturation signal to dendritic cells and activate the NF-kappa B pathway.
description
2000 nî lūn-bûn
@nan
2000年の論文
@ja
2000年学术文章
@wuu
2000年学术文章
@zh
2000年学术文章
@zh-cn
2000年学术文章
@zh-hans
2000年学术文章
@zh-my
2000年学术文章
@zh-sg
2000年學術文章
@yue
2000年學術文章
@zh-hant
name
Necrotic but not apoptotic cel ...... tivate the NF-kappa B pathway.
@en
Necrotic but not apoptotic cel ...... tivate the NF-kappa B pathway.
@nl
type
label
Necrotic but not apoptotic cel ...... tivate the NF-kappa B pathway.
@en
Necrotic but not apoptotic cel ...... tivate the NF-kappa B pathway.
@nl
prefLabel
Necrotic but not apoptotic cel ...... tivate the NF-kappa B pathway.
@en
Necrotic but not apoptotic cel ...... tivate the NF-kappa B pathway.
@nl
P2093
P356
P1476
Necrotic but not apoptotic cel ...... tivate the NF-kappa B pathway.
@en
P2093
P304
P356
10.1093/INTIMM/12.11.1539
P577
2000-11-01T00:00:00Z