Impact of deglycosylation and thermal stress on conformational stability of a full length murine IgG2a monoclonal antibody: observations from molecular dynamics simulations.

Impact of deglycosylation and thermal stress on conformational stability of a full length murine IgG2a monoclonal antibody: observations from molecular dynamics simulations.

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http://www.wikidata.org/entity/Q44540221
Advances in Antibody DesignOn the role of aggregation prone regions in protein evolution, stability, and enzymatic catalysis: insights from diverse analyses.The influence of N-linked glycans on the molecular dynamics of the HIV-1 gp120 V3 loop.High-throughput biophysical analysis and data visualization of conformational stability of an IgG1 monoclonal antibody after deglycosylation.Intramolecular immunological signal hypothesis revived--structural background of signalling revealed by using Congo Red as a specific tool.Consequences of glycan truncation on Fc structural integrity.Molecular basis of high viscosity in concentrated antibody solutions: Strategies for high concentration drug product developmentIn-silico prediction of concentration-dependent viscosity curves for monoclonal antibody solutions.Rational design of therapeutic mAbs against aggregation through protein engineering and incorporation of glycosylation motifs applied to bevacizumabMolecular dynamics simulation of the crystallizable fragment of IgG1-insights for the design of FcabsRational design of viscosity reducing mutants of a monoclonal antibody: hydrophobic versus electrostatic inter-molecular interactions.Concentration dependent viscosity of monoclonal antibody solutions: explaining experimental behavior in terms of molecular properties.Molecular Insights into the Thermal Stability of mAbs with Variable-Temperature Ion-Mobility Mass Spectrometry.
P2860

Impact of deglycosylation and thermal stress on conformational stability of a full length murine IgG2a monoclonal antibody: observations from molecular dynamics simulations.

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http://www.wikidata.org/entity/Q44540221
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2012 nî lūn-bûn
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2012年の論文
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2012年学术文章
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2012年学术文章
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2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
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2012年學術文章
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name
Impact of deglycosylation and ...... olecular dynamics simulations.
@en
Impact of deglycosylation and ...... olecular dynamics simulations.
@nl
type
label
Impact of deglycosylation and ...... olecular dynamics simulations.
@en
Impact of deglycosylation and ...... olecular dynamics simulations.
@nl
prefLabel
Impact of deglycosylation and ...... olecular dynamics simulations.
@en
Impact of deglycosylation and ...... olecular dynamics simulations.
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P5875
P698
P921
P356
P1433
P1476
Impact of deglycosylation and ...... olecular dynamics simulations.
@en
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P5875
P698
P921