Iron-binding characteristics of neuromelanin of the human substantia nigra.
about
Towards a unifying, systems biology understanding of large-scale cellular death and destruction caused by poorly liganded iron: Parkinson's, Huntington's, Alzheimer's, prions, bactericides, chemical toxicology and others as examplesThe role of oxidative stress in Parkinson's diseaseAgeing and Parkinson's disease: why is advancing age the biggest risk factor?Interactions of iron, dopamine and neuromelanin pathways in brain aging and Parkinson's diseaseMass spectrometry imaging, an emerging technology in neuropsychopharmacology.Synthesis and structural characterization of soluble neuromelanin analogs provides important clues to its biosynthesis.The role of iron in neurodegenerative disorders: insights and opportunities with synchrotron light.Alpha-synuclein redistributes to neuromelanin lipid in the substantia nigra early in Parkinson's disease.Dolichol is the major lipid component of human substantia nigra neuromelanin.Combined enrichment of neuromelanin granules and synaptosomes from human substantia nigra pars compacta tissue for proteomic analysis.Metal imaging in neurodegenerative diseases.Using high-resolution MR imaging at 7T to evaluate the anatomy of the midbrain dopaminergic system.Identification of L-ferritin in neuromelanin granules of the human substantia nigra: a targeted proteomics approachRasagiline: an anti-Parkinson drug with neuroprotective activity.Haem and non-haem iron intake through 17 years of adult life of a British Birth Cohort.The crucial role of metal ions in neurodegeneration: the basis for a promising therapeutic strategy.Interaction between Neuromelanin and Alpha-Synuclein in Parkinson's Disease.Imaging nigral pathology and clinical progression in Parkinson's disease.Genetics of iron regulation and the possible role of iron in Parkinson's disease.Iron toxicity in neurodegeneration.Considerations for measuring iron in post-mortem tissue of Parkinson's disease patients.Melanin affinity and its possible role in neurodegeneration.Neuromelanin of the human substantia nigra: an update.Protective and toxic roles of dopamine in Parkinson's disease.Biological metals and metal-targeting compounds in major neurodegenerative diseases.Alpha-synuclein: relating metals to structure, function and inhibition.Iron and dopamine: a toxic couple.Melanin and neuromelanin binding of drugs and chemicals: toxicological implications.Metals in Alzheimer's and Parkinson's Disease: Relevance to Dementia with Lewy Bodies.Alpha-synuclein and iron: two keys unlocking Parkinson's disease.Mechanisms of Gene-Environment Interactions in Parkinson's Disease.Neuromelanin enhances the toxicity of α-synuclein in SK-N-SH cells.Differential effects of human neuromelanin and synthetic dopamine melanin on neuronal and glial cells.Oxidative stress and neurological disorders in relation to blood lead levels in children.Substantia nigra neuromelanin-MR imaging differentiates essential tremor from Parkinson's disease.Substantia nigra neuromelanin magnetic resonance imaging in de novo Parkinson's disease patients.Magnetic resonance correlation of iron content with neuromelanin in the substantia nigra of early-stage Parkinson's disease.Neuromelanin detection by magnetic resonance imaging (MRI) and its promise as a biomarker for Parkinson's disease.Melanins: Skin Pigments and Much More—Types, Structural Models, Biological Functions, and Formation RoutesSerum ferritin is an important inflammatory disease marker, as it is mainly a leakage product from damaged cells
P2860
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P2860
Iron-binding characteristics of neuromelanin of the human substantia nigra.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年学术文章
@wuu
2003年学术文章
@zh
2003年学术文章
@zh-cn
2003年学术文章
@zh-hans
2003年学术文章
@zh-my
2003年学术文章
@zh-sg
2003年學術文章
@yue
2003年學術文章
@zh-hant
name
Iron-binding characteristics of neuromelanin of the human substantia nigra.
@en
Iron-binding characteristics of neuromelanin of the human substantia nigra.
@nl
type
label
Iron-binding characteristics of neuromelanin of the human substantia nigra.
@en
Iron-binding characteristics of neuromelanin of the human substantia nigra.
@nl
prefLabel
Iron-binding characteristics of neuromelanin of the human substantia nigra.
@en
Iron-binding characteristics of neuromelanin of the human substantia nigra.
@nl
P2093
P1476
Iron-binding characteristics of neuromelanin of the human substantia nigra
@en
P2093
Alfred X Trautwein
Dorit Ben-Shachar
Luigi Zecca
Manfred Gerlach
Mario Gallorini
Moussa B H Youdim
Peter Riederer
Volker Schünemann
P304
P356
10.1016/S0006-2952(03)00293-4
P407
P50
P577
2003-08-01T00:00:00Z