Oscillating fluid flow regulates gap junction communication in osteocytic MLO-Y4 cells by an ERK1/2 MAP kinase-dependent mechanism.
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Age-related changes in gap junctional intercellular communication in osteoblastic cellsMechanical stress-activated integrin α5β1 induces opening of connexin 43 hemichannels.Prostaglandin promotion of osteocyte gap junction function through transcriptional regulation of connexin 43 by glycogen synthase kinase 3/beta-catenin signaling.Enhanced osteoclastic resorption and responsiveness to mechanical load in gap junction deficient bone.Oscillating fluid flow activation of gap junction hemichannels induces ATP release from MLO-Y4 osteocytes.A Trabecular Bone Explant Model of Osteocyte-Osteoblast Co-Culture for Bone Mechanobiology.Activation of extracellular-signal regulated kinase (ERK1/2) by fluid shear is Ca(2+)- and ATP-dependent in MC3T3-E1 osteoblastsFinite element analyses of fluid flow conditions in cell culture.Lnk-dependent axis of SCF-cKit signal for osteogenesis in bone fracture healing.Gap junctional communication in osteocytes is amplified by low intensity vibrations in vitro.Cx43 and mechanotransduction in bone.Mechanical loading stimulates expression of connexin 43 in alveolar bone cells in the tooth movement model.Roles of gap junctions and hemichannels in bone cell functions and in signal transmission of mechanical stress.Inhibition of T-Type Voltage Sensitive Calcium Channel Reduces Load-Induced OA in Mice and Suppresses the Catabolic Effect of Bone Mechanical Stress on ChondrocytesMechanical regulation of signaling pathways in bone.Gap junctions and hemichannels in signal transmission, function and development of boneMolecular pathways mediating mechanical signaling in bone.Isolation and culture of primary osteocytes from the long bones of skeletally mature and aged miceGap Junctions and Biophysical Regulation of Bone CellsConnexin 43 deficiency attenuates loss of trabecular bone and prevents suppression of cortical bone formation during unloading.An Integrative Review of Mechanotransduction in Endothelial, Epithelial (Renal) and Dendritic Cells (Osteocytes).The molecular basis of bone mechanotransduction.Mechanosignaling in bone health, trauma and inflammation.Optimizing the osteogenic potential of adult stem cells for skeletal regeneration.The effect of mechanical strain on soft (cardiovascular) and hard (bone) tissues: common pathways for different biological outcomes.Shifting paradigms on the role of connexin43 in the skeletal response to mechanical load.Osteocyte physiology and response to fluid shear stress are impaired following exposure to cobalt and chromium: Implications for bone health following joint replacement.Bone cell mechanosensation of fluid flow stimulation: a fluid-structure interaction model characterising the role integrin attachments and primary cilia.Strain uses gap junctions to reverse stimulation of osteoblast proliferation by osteocytes.Fluid shear stress and melatonin in combination activate anabolic proteins in MC3T3-E1 osteoblast cells.Are all osteocytes equal? Multiscale modelling of cortical bone to characterise the mechanical stimulation of osteocytes.Increased sphingosine-1-phosphate production in response to osteocyte mechanotransduction.MAP kinase and calcium signaling mediate fluid flow-induced human mesenchymal stem cell proliferation.Joint diseases: from connexins to gap junctions.Role of connexin43 in osteoblast response to physical load.Combined Fluid Shear Stress and Melatonin Enhances the ERK/Akt/mTOR Signal in Cilia-Less MC3T3-E1 Preosteoblast Cells
P2860
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P2860
Oscillating fluid flow regulates gap junction communication in osteocytic MLO-Y4 cells by an ERK1/2 MAP kinase-dependent mechanism.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年学术文章
@wuu
2003年学术文章
@zh
2003年学术文章
@zh-cn
2003年学术文章
@zh-hans
2003年学术文章
@zh-my
2003年学术文章
@zh-sg
2003年學術文章
@yue
2003年學術文章
@zh-hant
name
Oscillating fluid flow regulat ...... AP kinase-dependent mechanism.
@en
Oscillating fluid flow regulat ...... AP kinase-dependent mechanism.
@nl
type
label
Oscillating fluid flow regulat ...... AP kinase-dependent mechanism.
@en
Oscillating fluid flow regulat ...... AP kinase-dependent mechanism.
@nl
prefLabel
Oscillating fluid flow regulat ...... AP kinase-dependent mechanism.
@en
Oscillating fluid flow regulat ...... AP kinase-dependent mechanism.
@nl
P2093
P1433
P1476
Oscillating fluid flow regulat ...... AP kinase-dependent mechanism.
@en
P2093
A I Alford
C R Jacobs
H J Donahue
P356
10.1016/S8756-3282(03)00167-4
P577
2003-07-01T00:00:00Z