Activation-independent parathyroid hormone receptor internalization is regulated by NHERF1 (EBP50). - Wikidata - awgldk - TriplyDB

Activation-independent parathyroid hormone receptor internalization is regulated by NHERF1 (EBP50).

Activation-independent parathyroid hormone receptor internalization is regulated by NHERF1 (EBP50).

http://www.wikidata.org/entity/Q44550523

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The CD34-related molecule podocalyxin is a potent inducer of microvillus formation NHERF1/EBP50 head-to-tail intramolecular interaction masks association with PDZ domain ligands The parathyroid hormone 1 receptor directly binds to the FERM domain of ezrin, an interaction that supports apical receptor localization and signaling in LLC-PK1 cells Regulation of G protein-coupled receptor function by Na+/H+ exchange regulatory factors Role of PDZ proteins in regulating trafficking, signaling, and function of GPCRs: means, motif, and opportunity Receptor activity-modifying protein (RAMP) isoform-specific regulation of adrenomedullin receptor trafficking by NHERF-1 Ezrin induces long-range interdomain allostery in the scaffolding protein NHERF1 Open conformation of ezrin bound to phosphatidylinositol 4,5-bisphosphate and to F-actin revealed by neutron scattering Sorting nexin 27 interacts with multidrug resistance-associated protein 4 (MRP4) and mediates internalization of MRP4 Parathyroid hormone receptor directly interacts with dishevelled to regulate beta-Catenin signaling and osteoclastogenesis.Gene profile analysis of osteoblast genes differentially regulated by histone deacetylase inhibitors.Deletion of the distal COOH-terminus of the A2B adenosine receptor switches internalization to an arrestin- and clathrin-independent pathway and inhibits recycling.The calcemic response to continuous parathyroid hormone (PTH)(1-34) infusion in end-stage kidney disease varies according to bone turnover: a potential role for PTH(7-84)Na/H exchanger regulatory factors control parathyroid hormone receptor signaling by facilitating differential activation of G(alpha) protein subunits.Formation of a ternary complex among NHERF1, beta-arrestin, and parathyroid hormone receptor.EBP50 inhibits the anti-mitogenic action of the parathyroid hormone type 1 receptor in vascular smooth muscle cells.Sustained cyclic AMP production by parathyroid hormone receptor endocytosis.Retromer terminates the generation of cAMP by internalized PTH receptors.A naturally occurring isoform inhibits parathyroid hormone receptor trafficking and signaling Dynamic Na+-H+ exchanger regulatory factor-1 association and dissociation regulate parathyroid hormone receptor trafficking at membrane microdomains International Union of Basic and Clinical Pharmacology. XCIII. The parathyroid hormone receptors--family B G protein-coupled receptors.Ubiquitination-deubiquitination balance dictates ligand-stimulated PTHR sorting.Mechanisms of ligand binding to the parathyroid hormone (PTH)/PTH-related protein receptor: selectivity of a modified PTH(1-15) radioligand for GalphaS-coupled receptor conformations Osteogenic regulation of vascular calcification: an early perspective.Structural basis for NHERF1 PDZ domain binding A PDZ-Like Motif in the Biliary Transporter ABCB4 Interacts with the Scaffold Protein EBP50 and Regulates ABCB4 Cell Surface Expression.The atypical antipsychotics clozapine and olanzapine promote down-regulation and display functional selectivity at human 5-HT7 receptors.Parathyroid hormone induces bone formation in phosphorylation-deficient PTHR1 knockin mice Ezrin-anchored protein kinase A coordinates phosphorylation-dependent disassembly of a NHERF1 ternary complex to regulate hormone-sensitive phosphate transport Arrestin scaffolds NHERF1 to the P2Y12 receptor to regulate receptor internalization.New concepts in drug discovery: collateral efficacy and permissive antagonism.Fluorescent ligand-directed co-localization of the parathyroid hormone 1 receptor with the brush-border scaffold complex of the proximal tubule reveals hormone-dependent changes in ezrin immunoreactivity consistent with inactivation Microarray gene expression profiling of osteoarthritic bone suggests altered bone remodelling, WNT and transforming growth factor-beta/bone morphogenic protein signalling.PTH(1-84)/PTH(7-84): a balance of power.Receptors as microprocessors: pharmacological nuance on metabotropic glutamate receptors 1alpha.Na/H exchange regulatory factor 1, a novel AKT-associating protein, regulates extracellular signal-regulated kinase signaling through a B-Raf-mediated pathway.Influence of the parathyroid glands on bone metabolism.Molecular basis of parathyroid hormone receptor signaling and trafficking: a family B GPCR paradigm.Regulation of parathyroid hormone type 1 receptor dynamics, traffic, and signaling by the Na+/H+ exchanger regulatory factor-1 in rat osteosarcoma ROS 17/2.8 cells.Sorting nexin 27 couples PTHR trafficking to retromer for signal regulation in osteoblasts during bone growth.

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P2860

Activation-independent parathyroid hormone receptor internalization is regulated by NHERF1 (EBP50).

http://www.wikidata.org/entity/Q44550523

description

2003 nî lūn-bûn

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2003年の論文

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2003年学术文章

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2003年学术文章

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2003年学术文章

@zh-cn

2003年学术文章

@zh-hans

2003年学术文章

@zh-my

2003年学术文章

@zh-sg

2003年學術文章

@yue

2003年學術文章

@zh-hant

name

Activation-independent parathy ...... s regulated by NHERF1 (EBP50).

@en

Activation-independent parathy ...... ization is regulated by NHERF1

@nl

type

label

Activation-independent parathy ...... s regulated by NHERF1 (EBP50).

@en

Activation-independent parathy ...... ization is regulated by NHERF1

@nl

prefLabel

Activation-independent parathy ...... s regulated by NHERF1 (EBP50).

@en

Activation-independent parathy ...... ization is regulated by NHERF1

@nl

P1433

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P1433

Journal of Biological Chemistry

P1476

Activation-independent parathy ...... s regulated by NHERF1 (EBP50).

@en

P2093

Alessandro Bisello

http://www.w3.org/2001/XMLSchema#string

Clara E Magyar

http://www.w3.org/2001/XMLSchema#string

Colin A Syme

http://www.w3.org/2001/XMLSchema#string

Edward J Weinman

http://www.w3.org/2001/XMLSchema#string

Jean-Luc Parent

http://www.w3.org/2001/XMLSchema#string

Moulay Driss Rochdi

http://www.w3.org/2001/XMLSchema#string

Peter A Friedman

http://www.w3.org/2001/XMLSchema#string

W Bruce Sneddon

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P2860

Unexpected modes of PDZ domain scaffolding revealed by structure of nNOS-syntrophin complex

The B1 subunit of the H+ATPase is a PDZ domain-binding protein. Colocalization with NHE-RF in renal B-intercalated cells

A kinase-regulated PDZ-domain interaction controls endocytic sorting of the beta2-adrenergic receptor

Na(+)/H(+ ) exchanger regulatory factor 2 directs parathyroid hormone 1 receptor signalling

The adenosine 2b receptor is recruited to the plasma membrane and associates with E3KARP and Ezrin upon agonist stimulation

Ezrin-radixin-moesin-binding phosphoprotein-50/Na+/H+ exchanger regulatory factor (EBP50/NHERF) blocks U50,488H-induced down-regulation of the human kappa opioid receptor by enhancing its recycling rate

Regulation of GTP-binding protein alpha q (Galpha q) signaling by the ezrin-radixin-moesin-binding phosphoprotein-50 (EBP50)

ERM proteins and merlin: integrators at the cell cortex

A role for N-cadherin in the development of the differentiated osteoblastic phenotype.

Cellular distribution of constitutively active mutant parathyroid hormone (PTH)/PTH-related protein receptors and regulation of cyclic adenosine 3',5'-monophosphate signaling by beta-arrestin2.

P304

43787-43796

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scholarly article

P356

10.1074/JBC.M306019200

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P407

P433

44

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P478

278

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P50

Abdul B Abou-Samra

P577

2003-08-14T00:00:00Z

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P698

12920119

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