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Functions of Cationic Host Defense Peptides in ImmunityVitamin D in a northern Canadian first nation population: dietary intake, serum concentrations and functional gene polymorphismsUltrashort cationic lipopeptides and lipopeptoids selectively induce cytokine production in macrophagesEffect of vitamin D supplementation on Mycobacterium tuberculosis-induced innate immune responses in a Canadian Dené First Nations cohortModulation of interleukin-1β-induced inflammatory responses by a synthetic cationic innate defence regulator peptide, IDR-1002, in synovial fibroblastsBovine toll-like receptor 9: a comparative analysis of molecular structure, function and expression.Host defence peptides from invertebrates--emerging antimicrobial strategies.Cationic host defence peptides: innate immune regulatory peptides as a novel approach for treating infections.Cathelicidins and functional analogues as antisepsis molecules.Cationic host defence peptides: multifaceted role in immune modulation and inflammation.Nucleic acids exert a sequence-independent cooperative effect on sequence-dependent activation of Toll-like receptor 9.TLR9-/- and TLR9+/+ mice display similar immune responses to a DNA vaccine.Systems biology evaluation of immune responses induced by human host defence peptide LL-37 in mononuclear cells.Buprenorphine Alters Inflammatory and Oxidative Stress Molecular Markers in Arthritis.The biochemical signatures of stress: A preliminary analysis of osteocalcin concentrations and macroscopic skeletal changes associated with stress in the 13th - 17th centuries black friars population.Defining TNF-α and IL-1β induced nascent proteins: combining bio-orthogonal non-canonical amino acid tagging and proteomics.Bovine and human cathelicidin cationic host defense peptides similarly suppress transcriptional responses to bacterial lipopolysaccharide.Modulation of the TLR-mediated inflammatory response by the endogenous human host defense peptide LL-37.Amphiphilic tobramycins with immunomodulatory properties.The human host defense peptide LL-37 induces apoptosis in a calpain- and apoptosis-inducing factor-dependent manner involving Bax activity.Multiple immune-modulatory functions of cathelicidin host defense peptides.High degree of correlation between whole blood and PBMC expression levels of miR-155 and miR-146a in healthy controls and rheumatoid arthritis patients.Whole blood microRNA expression pattern differentiates patients with rheumatoid arthritis, their seropositive first-degree relatives, and healthy unrelated control subjects.Inhaled Diesel Exhaust Decreases Antimicrobial Peptides Alpha-defensin and S100A7 in Human Bronchial Secretion.An anti-infective peptide that selectively modulates the innate immune response.Cytokines IL-17, TNF and IFN-γ Alter the Expression of Antimicrobial Peptides and Proteins Disparately: A Targeted Proteomics Analysis using SOMAscan TechnologySurface molecules of procyclic forms of Trypanosoma simiae and Trypanosoma congolense, members of the subgenus Nannomonas, share immunodominant carbohydrate epitopesInflammatory cytokines IL-32 and IL-17 have common signaling intermediates despite differential dependence on TNF-receptor 1Defining the mechanism of action of herbal therapies in rheumatoid arthritis: is this the road to clinical development and acceptance?Human cathelicidin LL-37-derived peptide IG-19 confers protection in a murine model of collagen-induced arthritisHuman cathelicidin LL-37 and its derivative IG-19 regulate interleukin-32-induced inflammationImmunomodulatory innate defence regulator (IDR) peptide alleviates airway inflammation and hyper-responsivenessAntimicrobial host defence peptides: functions and clinical potentialImmunomodulatory Functions of the Human Cathelicidin LL-37 (aa 13-31)-Derived Peptides are Associated with Predicted α-Helical Propensity and Hydrophobic IndexPolymorphisms in the P2X7 receptor, and differential expression of Toll-like receptor-mediated cytokines and defensins, in a Canadian Indigenous group
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onderzoeker
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հետազոտող
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Neeloffer Mookherjee
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Neeloffer Mookherjee
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Neeloffer Mookherjee
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Neeloffer Mookherjee
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Neeloffer Mookherjee
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Neeloffer Mookherjee
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Neeloffer Mookherjee
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Neeloffer Mookherjee
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Neeloffer Mookherjee
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0000-0002-9350-4157