Insulin regulation of heart function in aging fruit flies.
about
Over-expression of DSCAM and COL6A2 cooperatively generates congenital heart defectsSestrins at the crossroad between stress and agingKCNQ potassium channel mutations cause cardiac arrhythmias in Drosophila that mimic the effects of aging.Using Drosophila to discover mechanisms underlying type 2 diabetesMethods to assess Drosophila heart development, function and agingGrowth factors, nutrient signaling, and cardiovascular agingComparative approaches to the study of physiology: Drosophila as a physiological tool.Genetic variation for cardiac dysfunction in DrosophilaPGC-1/Spargel Counteracts High-Fat-Diet-Induced Obesity and Cardiac Lipotoxicity Downstream of TOR and Brummer ATGL Lipase.A Drosophila model of high sugar diet-induced cardiomyopathydJun and Vri/dNFIL3 are major regulators of cardiac aging in DrosophilaSPARC-Dependent Cardiomyopathy in Drosophila.Lifespan extension by preserving proliferative homeostasis in DrosophilaExercise-training in young Drosophila melanogaster reduces age-related decline in mobility and cardiac performanceThe role of insulin/IGF-1 signaling in the longevity of model invertebrates, C. elegans and D. melanogasterMultiple measures of functionality exhibit progressive decline in a parallel, stochastic fashion in Drosophila Sod2 null mutantsMitochondrial dysfunction in cardiac agingTinman/Nkx2-5 acts via miR-1 and upstream of Cdc42 to regulate heart function across speciesSestrin as a feedback inhibitor of TOR that prevents age-related pathologiesThe cell-non-autonomous nature of electron transport chain-mediated longevityDrosophila as a model for the identification of genes causing adult human heart disease.d4eBP acts downstream of both dTOR and dFoxo to modulate cardiac functional aging in Drosophila.Dystrophin deficiency in Drosophila reduces lifespan and causes a dilated cardiomyopathy phenotype.A new method for detection and quantification of heartbeat parameters in Drosophila, zebrafish, and embryonic mouse heartsHigh-fat-diet-induced obesity and heart dysfunction are regulated by the TOR pathway in DrosophilaROS regulate cardiac function via a distinct paracrine mechanism.Time-restricted feeding attenuates age-related cardiac decline in DrosophilaMolecular evolution and functional characterization of Drosophila insulin-like peptidesA dual role for integrin-linked kinase and β1-integrin in modulating cardiac aging.Non-autonomous modulation of heart rhythm, contractility and morphology in adult fruit flies.Drosophila as a Model for Diabetes and Diseases of Insulin Resistance.Studying aging in Drosophila.Cardiac aging in mice and humans: the role of mitochondrial oxidative stressRegulation of Drosophila Lifespan by bellwether Promoter Alleles.SH2B regulation of growth, metabolism, and longevity in both insects and mammals.Genotype-by-diet interactions drive metabolic phenotype variation in Drosophila melanogaster.The FoxO family in cardiac function and dysfunction.Intertissue control of the nucleolus via a myokine-dependent longevity pathway.Drosophila KCNQ channel displays evolutionarily conserved electrophysiology and pharmacology with mammalian KCNQ channels.Ageing in Drosophila: the role of the insulin/Igf and TOR signalling network.
P2860
Q21563377-D71B55FD-C91E-4B29-B081-E902A7BB08B9Q24633564-B26F0BC8-CF30-4E64-8C2A-6B06647D8E4DQ24681227-A8590C34-C1EA-4A35-BBA7-DEADE03CF2B9Q26751078-064AEF1A-F520-489D-B067-37168370A5CAQ26822579-4FB01BC3-02D5-4850-BE68-9614679E86AFQ26852243-AB94DBF1-FC96-4FEB-85EF-5EF526B8F76AQ27015827-3B9DD323-1D94-43EF-BFE6-C2D5F7895713Q27302935-525B0F48-ACEA-4588-A93B-C18A098928DEQ27321131-E3900503-BCF8-4EDF-9325-BFC840E1F77DQ27325739-10042105-70CE-48BD-A2F4-5533BC69A7D4Q27329717-61754EF6-F745-40E2-9009-93458DEC67CCQ27340405-76644D97-1CBC-4D7A-AF90-D0A6DBE8F801Q27345444-8B1D4C76-3832-4B73-A5A5-261109DBF59DQ27348552-CCA7604B-099D-419A-A06A-E0A2E9EF1C01Q28083445-FBE13799-98A1-4495-B4F9-E156604F8D17Q28306903-ED421400-915D-45BB-BD76-1DA93220D59EQ28389063-06767785-C451-49D0-AEEB-1EE40E122BC8Q28511985-3F08BFAE-8365-411E-8FE6-E3A6A2781DF8Q28590387-10FC7895-DC79-4382-AED3-EE5C3EFD922FQ29617238-7CD454EF-B2EE-4B14-AA81-9F990C4C5500Q30476715-6A7CD798-64F3-4C8B-A1E8-D37F56D79255Q30493481-8B18C7CC-2EEB-475C-9CF0-CBA3CB517EF2Q30493760-F0837FC7-B26B-4730-AB69-E9548569EE7CQ30494115-9C7635E6-6437-4AE7-AFAE-9E277E2DA495Q30497986-C74D9E9D-FEBE-4991-8C7E-E293B2003B95Q30586973-1A074ADF-E187-4AD1-BDA6-97CEB5BC13D4Q30665184-7CF29E7A-1750-417F-BD66-44BFCE132317Q33535892-0054AE96-4188-4E31-879B-28B27C07FF45Q33656535-808F1537-42E9-4F30-884A-7FBCA8D96E1FQ33693863-653EC2D7-70F2-47EF-9FCF-302D4E20419FQ33726975-C585C45C-5CF1-49CD-91BA-6F7F4AF8F470Q33791037-F41011F2-FB3B-4569-94AC-DD24200DF4C3Q33806910-B30E5639-4F0C-4A64-A9DE-5CF9005B8AF0Q33829934-A4B0CF50-DC17-4A2B-A2F7-A3AA6C9B66BBQ33898278-65E02309-AE14-44BF-B289-8586B8322592Q34007830-3CE8B8E0-252F-4516-A69D-DA080DB8949EQ34013124-359A2DE2-6A23-41E8-9F96-6FB1EAB213B7Q34018412-F93FCD29-43BF-4B88-8D1F-D50752448D31Q34018870-3A1FD90F-E844-4B4E-9E3A-B791BE8A4796Q34024014-4DDCC733-6247-4E15-899A-F59ADF4BDB83
P2860
Insulin regulation of heart function in aging fruit flies.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年学术文章
@wuu
2004年学术文章
@zh
2004年学术文章
@zh-cn
2004年学术文章
@zh-hans
2004年学术文章
@zh-my
2004年学术文章
@zh-sg
2004年學術文章
@yue
2004年學術文章
@zh-hant
name
Insulin regulation of heart function in aging fruit flies.
@en
Insulin regulation of heart function in aging fruit flies.
@nl
type
label
Insulin regulation of heart function in aging fruit flies.
@en
Insulin regulation of heart function in aging fruit flies.
@nl
prefLabel
Insulin regulation of heart function in aging fruit flies.
@en
Insulin regulation of heart function in aging fruit flies.
@nl
P2093
P356
P1433
P1476
Insulin regulation of heart function in aging fruit flies.
@en
P2093
Erin Fitzgerald
Robert J Wessells
Rolf Bodmer
P2888
P304
P356
10.1038/NG1476
P407
P577
2004-11-21T00:00:00Z