Extended life span is associated with insulin resistance in a transgenic mouse model of insulinoma secreting human islet amyloid polypeptide.

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Amylin and its analogs: a friend or foe for the treatment of Alzheimer's disease?The ability of rodent islet amyloid polypeptide to inhibit amyloid formation by human islet amyloid polypeptide has important implications for the mechanism of amyloid formation and the design of inhibitors.

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Extended life span is associated with insulin resistance in a transgenic mouse model of insulinoma secreting human islet amyloid polypeptide.

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2003 nî lūn-bûn

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2003年の論文

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2003年学术文章

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2003年学术文章

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2003年学术文章

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2003年学术文章

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2003年学术文章

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2003年学术文章

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2003年學術文章

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2003年學術文章

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name

Extended life span is associat ...... man islet amyloid polypeptide.

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Extended life span is associat ...... man islet amyloid polypeptide.

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type

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Extended life span is associat ...... man islet amyloid polypeptide.

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Extended life span is associat ...... man islet amyloid polypeptide.

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Extended life span is associat ...... man islet amyloid polypeptide.

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Extended life span is associat ...... man islet amyloid polypeptide.

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P1476

Extended life span is associat ...... man islet amyloid polypeptide.

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P2093

C Bruce Verchere

http://www.w3.org/2001/XMLSchema#string

Feng Wang

http://www.w3.org/2001/XMLSchema#string

Lucy Marzban

http://www.w3.org/2001/XMLSchema#string

Rebecca L Hull

http://www.w3.org/2001/XMLSchema#string

Shani M Wilbur

http://www.w3.org/2001/XMLSchema#string

Sofianos Andrikopoulos

http://www.w3.org/2001/XMLSchema#string

Steven E Kahn

http://www.w3.org/2001/XMLSchema#string

Thomas N Wight

http://www.w3.org/2001/XMLSchema#string

P2860

Pancreatic islet cell toxicity of amylin associated with type-2 diabetes mellitus

Purification and characterization of a peptide from amyloid-rich pancreases of type 2 diabetic patients

The prohormone convertase enzyme 2 (PC2) is essential for processing pro-islet amyloid polypeptide at the NH2-terminal cleavage site

Conservation of the sequence of islet amyloid polypeptide in five mammals is consistent with its putative role as an islet hormone

Islet amyloid polypeptide: pinpointing amino acid residues linked to amyloid fibril formation

Processing of synthetic pro-islet amyloid polypeptide (proIAPP) 'amylin' by recombinant prohormone convertase enzymes, PC2 and PC3, in vitro.

Islet amyloid: a long-recognized but underappreciated pathological feature of type 2 diabetes.

Beta-cell lines derived from transgenic mice expressing a hybrid insulin gene-oncogene.

A novel peptide in the calcitonin gene related peptide family as an amyloid fibril protein in the endocrine pancreas.

Islet amyloid formation associated with hyperglycemia in transgenic mice with pancreatic beta cell expression of human islet amyloid polypeptide.

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scholarly article

P356

10.1152/AJPENDO.00137.2003

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286

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2003-11-12T00:00:00Z

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9012030

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14613923

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Extended life span is associated with insulin resistance in a transgenic mouse model of insulinoma secreting human islet amyloid polypeptide.

about

P2860

P2860

Extended life span is associated with insulin resistance in a transgenic mouse model of insulinoma secreting human islet amyloid polypeptide.

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