Specific excision of the selenocysteine tRNA[Ser]Sec (Trsp) gene in mouse liver demonstrates an essential role of selenoproteins in liver function.
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Osteo-chondroprogenitor-specific deletion of the selenocysteine tRNA gene, Trsp, leads to chondronecrosis and abnormal skeletal development: a putative model for Kashin-Beck diseaseMammalian ALKBH8 possesses tRNA methyltransferase activity required for the biogenesis of multiple wobble uridine modifications implicated in translational decodingPhysiological Roles of Adipokines, Hepatokines, and Myokines in RuminantsSelenium and diabetes--evidence from animal studiesCytoprotective Nrf2 pathway is induced in chronically txnrd 1-deficient hepatocytesMetabolic Adaptation in Obesity and Type II Diabetes: Myokines, Adipokines and HepatokinesPathophysiology of Non Alcoholic Fatty Liver DiseaseTrxR1 as a potent regulator of the Nrf2-Keap1 response systemBasic principles and emerging concepts in the redox control of transcription factorsParadoxical Roles of Antioxidant Enzymes: Basic Mechanisms and Health ImplicationsMechanisms of activation of the transcription factor Nrf2 by redox stressors, nutrient cues, and energy status and the pathways through which it attenuates degenerative diseaseMammalian thioredoxin reductase 1: roles in redox homoeostasis and characterization of cellular targetsSecisbp2 is essential for embryonic development and enhances selenoprotein expressionSelenoprotein P controls oxidative stress in corneaSelenoproteins regulate macrophage invasiveness and extracellular matrix-related gene expression.The RNA-binding protein Secisbp2 differentially modulates UGA codon reassignment and RNA decay.Analysis of methionine/selenomethionine oxidation and methionine sulfoxide reductase function using methionine-rich proteins and antibodies against their oxidized forms.The distal sequence element of the selenocysteine tRNA gene is a tissue-dependent enhancer essential for mouse embryogenesisThe syndrome of inherited partial SBP2 deficiency in humans.Selenoproteins: molecular pathways and physiological roles.Inverse correlation between serum levels of selenoprotein P and adiponectin in patients with type 2 diabetes.Biosynthesis of selenocysteine, the 21st amino acid in the genetic code, and a novel pathway for cysteine biosynthesis.Assessment of the Selenoprotein M (SELM) over-expression on human hepatocellular carcinoma tissues by immunohistochemistry.Role of selenium-containing proteins in T-cell and macrophage function.Trace metal imaging in diagnostic of hepatic metal disease.High-resolution imaging of selenium in kidneys: a localized selenium pool associated with glutathione peroxidase 3.Regulation of Selenocysteine Content of Human Selenoprotein P by Dietary Selenium and Insertion of Cysteine in Place of SelenocysteineSelenoprotein expression is essential in endothelial cell development and cardiac muscle functionMore roles for selenoprotein P: local selenium storage and recycling protein in the brain.Understanding selenoprotein function and regulation through the use of rodent models.Mouse models targeting selenocysteine tRNA expression for elucidating the role of selenoproteins in health and development.Loss of housekeeping selenoprotein expression in mouse liver modulates lipoprotein metabolismProduction of selenoprotein P (Sepp1) by hepatocytes is central to selenium homeostasisThioredoxin reductase 1 protects against chemically induced hepatocarcinogenesis via control of cellular redox homeostasis.A functional link between housekeeping selenoproteins and phase II enzymes.Glutathione peroxidase 4 and vitamin E cooperatively prevent hepatocellular degenerationSelenoprotein H is an essential regulator of redox homeostasis that cooperates with p53 in development and tumorigenesisThe selenocysteine tRNA STAF-binding region is essential for adequate selenocysteine tRNA status, selenoprotein expression and early age survival of mice.Plasma selenium levels and nonalcoholic fatty liver disease in Chinese adults: a cross-sectional analysis.Metformin suppresses expression of the selenoprotein P gene via an AMP-activated kinase (AMPK)/FoxO3a pathway in H4IIEC3 hepatocytes.
P2860
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P2860
Specific excision of the selenocysteine tRNA[Ser]Sec (Trsp) gene in mouse liver demonstrates an essential role of selenoproteins in liver function.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年学术文章
@wuu
2003年学术文章
@zh-cn
2003年学术文章
@zh-hans
2003年学术文章
@zh-my
2003年学术文章
@zh-sg
2003年學術文章
@yue
2003年學術文章
@zh
2003年學術文章
@zh-hant
name
Specific excision of the selen ...... enoproteins in liver function.
@en
Specific excision of the selenocysteine tRNA[Ser]Sec
@nl
type
label
Specific excision of the selen ...... enoproteins in liver function.
@en
Specific excision of the selenocysteine tRNA[Ser]Sec
@nl
prefLabel
Specific excision of the selen ...... enoproteins in liver function.
@en
Specific excision of the selenocysteine tRNA[Ser]Sec
@nl
P2093
P356
P1476
Specific excision of the selen ...... enoproteins in liver function.
@en
P2093
Bradley A Carlson
Byeong Jae Lee
Dolph L Hatfield
Easwari Kumaraswamy
Miriam R Anver
Vadim N Gladyshev
P304
P356
10.1074/JBC.M310470200
P407
P577
2003-12-04T00:00:00Z