Discovery of a bulky 2-tert-butyl group containing primaquine analogue that exhibits potent blood-schizontocidal antimalarial activities and complete elimination of methemoglobin toxicity.
about
Synthesis, antimalarial, antileishmanial, antimicrobial, cytotoxicity, and methemoglobin (MetHB) formation activities of new 8-quinolinaminesSynthesis, antiprotozoal, antimicrobial, β-hematin inhibition, cytotoxicity and methemoglobin (MetHb) formation activities of bis(8-aminoquinolines).Methemoglobinemia caused by 8-aminoquinoline drugs: DFT calculations suggest an analogy to H4B's role in nitric oxide synthase.Rational ligand design for the arylation of hindered primary amines guided by reaction progress kinetic analysis.2-tert-butyl-8-quinolinamines exhibit potent blood schizontocidal antimalarial activity via inhibition of heme crystallization.Synthesis and evaluation of naphthyridine compounds as antimalarial agentsStructural modifications of quinoline-based antimalarial agents: Recent developments.Electrospray ionization mass spectrometry as a valuable tool in the characterization of novel primaquine peptidomimetic derivatives.
P2860
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P2860
Discovery of a bulky 2-tert-butyl group containing primaquine analogue that exhibits potent blood-schizontocidal antimalarial activities and complete elimination of methemoglobin toxicity.
description
2004 nî lūn-bûn
@nan
2004年の論文
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2004年学术文章
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2004年学术文章
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2004年学术文章
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2004年学术文章
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2004年学术文章
@zh-sg
2004年學術文章
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2004年學術文章
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2004年學術文章
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name
Discovery of a bulky 2-tert-bu ...... ion of methemoglobin toxicity.
@en
Discovery of a bulky 2-tert-bu ...... ion of methemoglobin toxicity.
@nl
type
label
Discovery of a bulky 2-tert-bu ...... ion of methemoglobin toxicity.
@en
Discovery of a bulky 2-tert-bu ...... ion of methemoglobin toxicity.
@nl
prefLabel
Discovery of a bulky 2-tert-bu ...... ion of methemoglobin toxicity.
@en
Discovery of a bulky 2-tert-bu ...... ion of methemoglobin toxicity.
@nl
P2093
P356
P1476
Discovery of a bulky 2-tert-bu ...... tion of methemoglobin toxicity
@en
P2093
Chaman L Kaul
Gopa B Jena
Meenakshi Jain
Poduri Ramarao
Prati P Singh
Rahul Jain
Sandeep Sachdeva
Savita Singh
Suryanarayana Vangapandu
P304
P356
10.1021/JM0304562
P407
P577
2004-01-01T00:00:00Z