Recombinant adeno-associated virus-mediated alpha-1 antitrypsin gene therapy prevents type I diabetes in NOD mice.
about
T Helper Subsets, Peripheral Plasticity, and the Acute Phase Protein, α1-AntitrypsinAcute-phase protein α1-anti-trypsin: diverting injurious innate and adaptive immune responses from non-authentic threatsMechanistic evidence in support of alpha1-antitrypsin as a therapeutic approach for type 1 diabetesExpanding the clinical indications for α(1)-antitrypsin therapyTwo single nucleotide polymorphisms sites in α1-AT gene and their association with somatic cell score in Chinese Holstein cows.Alpha1-antitrypsin monotherapy prolongs islet allograft survival in mice.RETRACTED: Activation of the NF-kappaB pathway by adeno-associated virus (AAV) vectors and its implications in immune response and gene therapyGenetic vaccination for re-establishing T-cell tolerance in type 1 diabetes.Pancreatic islet xenograft survival in mice is extended by a combination of alpha-1-antitrypsin and single-dose anti-CD4/CD8 therapy.α-1-antitrypsin gene delivery reduces inflammation, increases T-regulatory cell population size and prevents islet allograft rejectionInhibition of IL-32 activation by α-1 antitrypsin suppresses alloreactivity and increases survival in an allogeneic murine marrow transplantation model.Recombinant adeno-associated virus vectors for gene therapy.Gene therapy progress and prospects: gene therapy for diabetes mellitus.Alpha 1 Antitrypsin Inhibits Dendritic Cell Activation and Attenuates Nephritis in a Mouse Model of Lupus.Precise hit: adeno-associated virus in gene targeting.Translational mini-review series on type 1 diabetes: Immune-based therapeutic approaches for type 1 diabetes.Transgene therapy for rat anti-Thy1.1 glomerulonephritis via mesangial cell vector with a polyethylenimine/decorin nanocomplexEffect of recombinant α1-antitrypsin Fc-fused (AAT-Fc)protein on the inhibition of inflammatory cytokine production and streptozotocin-induced diabetes.Allogeneic islet transplantation.Ex vivo gene transfer of viral interleukin-10 to BB rat islets: no protection after transplantation to diabetic BB rats.Distinct immune responses to transgene products from rAAV1 and rAAV8 vectorsLung disease associated with alpha1-antitrypsin deficiency.Alpha-1 antitrypsin: a potent anti-inflammatory and potential novel therapeutic agent.Par-4 as a potential target for cancer therapy.Immune-modulating effects of alpha-1 antitrypsin.Alpha-1 antitrypsin inhibits RANKL-induced osteoclast formation and functionsAlpha-1 antitrypsin protein and gene therapies decrease autoimmunity and delay arthritis development in mouse model.The circulating proteinase inhibitor α-1 antitrypsin regulates neutrophil degranulation and autoimmunity.Molecular multitasking in the airspace: alpha1-antitrypsin takes on thrombin and plasminHuman alpha 1-antitrypsin therapy induces fatal anaphylaxis in non-obese diabetic mice.Well-Known and Less Well-Known Functions of Alpha-1 Antitrypsin. Its Role in Chronic Obstructive Pulmonary Disease and Other Disease Developments.Novel therapeutic uses of alpha-1 antitrypsin: a window to the future.Therapies to Suppress β Cell Autoimmunity in Type 1 Diabetes
P2860
Q26829272-FD3C9FB4-4DDF-45F5-A3D6-553E1F906516Q26858837-B61015BF-80C8-40E4-96C8-958559B02AADQ26861561-52DAA402-58D4-4692-BE32-DB898BCA8A1CQ27000764-6C39B605-8669-4C50-A6AD-252BB77CF3D3Q33560575-B992AB5B-6EE3-4C63-898F-35B2905BA96BQ33922982-30628DAC-B493-4064-A04D-A8C25EA701F7Q34621544-8004093D-9A00-4481-9EBC-F1A174F2A918Q34706913-CC24C8B3-5844-4715-AB9D-A029C166C53CQ34744307-FB9F7B7C-3D41-4B45-9830-10420318929CQ35286904-04B6EDE5-55E4-4A79-A94F-4999B6274BE0Q35525740-8C9ED260-4B07-4F7A-A735-5792A6635F66Q35842668-029303FB-49B2-45E2-98E9-F504E4B460A0Q35924387-867A520C-9936-4EF8-9240-F7AE46008717Q36032325-4C727E69-1688-40A9-A41C-33BAF33C29D4Q36302317-9689F52B-74C5-4CD7-A6B5-F65A5B5A06A8Q36755915-03BC44F7-BF65-41C0-9A08-C1313DE2828DQ36776280-1BD83E3D-E912-4B32-89B0-A57CBC02229DQ36885672-5BFF811C-F624-4392-9EC4-EE2E6268B97DQ36981652-31B315F2-A123-4ECC-AFDF-902DA8E6BA20Q37295677-C9E04189-404F-48A3-9875-9BC9D1A232F3Q37385999-976929F8-145F-469D-8CF6-4BC7A013238EQ37804626-77BC19B2-7C79-422F-A3FA-1EECC11A2C29Q37986292-8B97E383-91B5-41BC-8CE4-17A89F38270CQ38051738-4ACFC943-4ED0-43FA-BDC5-D77715C5ADD2Q38214040-2DF8B290-4EF2-4B8E-9E49-55B87A1182C0Q38711081-43BADAE9-9057-4D65-AB3D-C55544662652Q39587262-28D54D1B-7D0D-4CCA-938B-653DF08083FEQ42234561-D291EC42-6AFE-41C8-9C65-CFF9ED9EBA14Q42375019-C35EDBED-AF98-45D1-9BBF-2CB24D8A68C6Q46401098-B8A2620D-09D7-44B7-833C-F18665E02E22Q51465416-30A5019D-169F-4E02-97E9-73AA9C6DFD6AQ51534901-1CC73D0E-D1A5-492C-9569-FA0EA7C0A684Q58773667-62AEF9B1-D76A-48CD-8D78-43B1F7094E10
P2860
Recombinant adeno-associated virus-mediated alpha-1 antitrypsin gene therapy prevents type I diabetes in NOD mice.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年学术文章
@wuu
2004年学术文章
@zh-cn
2004年学术文章
@zh-hans
2004年学术文章
@zh-my
2004年学术文章
@zh-sg
2004年學術文章
@yue
2004年學術文章
@zh
2004年學術文章
@zh-hant
name
Recombinant adeno-associated v ...... s type I diabetes in NOD mice.
@en
Recombinant adeno-associated v ...... s type I diabetes in NOD mice.
@nl
type
label
Recombinant adeno-associated v ...... s type I diabetes in NOD mice.
@en
Recombinant adeno-associated v ...... s type I diabetes in NOD mice.
@nl
prefLabel
Recombinant adeno-associated v ...... s type I diabetes in NOD mice.
@en
Recombinant adeno-associated v ...... s type I diabetes in NOD mice.
@nl
P2093
P2860
P356
P1433
P1476
Recombinant adeno-associated v ...... s type I diabetes in NOD mice.
@en
P2093
Atkinson MA
Crawford JM
Scott-Jorgensen M
P2860
P2888
P304
P356
10.1038/SJ.GT.3302156
P577
2004-01-01T00:00:00Z