B cell developmental requirement for the G alpha i2 gene.
about
Defects in mucosal immunity leading to Crohn's diseaseCannabinoid receptor 2 is critical for the homing and retention of marginal zone B lineage cells and for efficient T-independent immune responsesB Lymphocyte-Specific Loss of Ric-8A Results in a Gα Protein Deficit and Severe Humoral Immunodeficiency.Expanded B cell population blocks regulatory T cells and exacerbates ileitis in a murine model of Crohn diseaseIL-10-producing regulatory B cells induced by IL-33 (Breg(IL-33)) effectively attenuate mucosal inflammatory responses in the gut.Defective chemokine signal integration in leukocytes lacking activator of G protein signaling 3 (AGS3)Loss of Gαi proteins impairs thymocyte development, disrupts T-cell trafficking, and leads to an expanded population of splenic CD4+PD-1+CXCR5+/- T-cellsMesenteric B cells centrally inhibit CD4+ T cell colitis through interaction with regulatory T cell subsets.Implications of non-canonical G-protein signaling for the immune systemVariations in Gnai2 and Rgs1 expression affect chemokine receptor signaling and the organization of secondary lymphoid organs.CD4+FoxP3+ regulatory T cells from Gαi2-/- mice are functionally active in vitro, but do not prevent colitisG alpha q-containing G proteins regulate B cell selection and survival and are required to prevent B cell-dependent autoimmunityAbundant and diverse fungal microbiota in the murine intestine.IL-10-producing regulatory B10 cells inhibit intestinal injury in a mouse modelThe loss of Gnai2 and Gnai3 in B cells eliminates B lymphocyte compartments and leads to a hyper-IgM like syndrome.Pleiotropic phenotype of a genomic knock-in of an RGS-insensitive G184S Gnai2 alleleSignaling in transitional type 2 B cells is critical for peripheral B-cell development.Development and selection of marginal zone B cells.Peripheral CD5+ B cells in antineutrophil cytoplasmic antibody-associated vasculitis.Systems-wide analysis of BCR signalosomes and downstream phosphorylation and ubiquitylation.CD19 expression in B cells is important for suppression of contact hypersensitivity.T regulatory cells and B cells cooperate to form a regulatory loop that maintains gut homeostasis and suppresses dextran sulfate sodium-induced colitisInducible IL10(+) suppressor B cells inhibit CNS inflammation and T helper 17 polarization.Characterization of marginal zone B cell precursors.Immunopathogenesis of IBD: insufficient suppressor function in the gut?Integration of B cells and CD8+ T in the protective regulation of systemic epithelial inflammation.Colitis immunoregulation by CD8+ T cell requires T cell cytotoxicity and B cell peptide antigen presentationCD5 plays an inhibitory role in the suppressive function of murine CD4(+) CD25(+) T(reg) cellsAlterations in myeloid dendritic cell innate immune responses in the Galphai2-deficient mouse model of colitis.Regulatory B cells in autoimmune diseases and mucosal immune homeostasisNot always the bad guys: B cells as regulators of autoimmune pathology.Villous B cells of the small intestine are specialized for invariant NK T cell dependenceAnimal models of ulcerative colitis and their application in drug research.Signaling through Galphai2 protein is required for recruitment of neutrophils for antibody-mediated elimination of larval Strongyloides stercoralis in mice.Resident enteric microbiota and CD8+ T cells shape the abundance of marginal zone B cells.Suppressive functions of activated B cells in autoimmune diseases reveal the dual roles of Toll-like receptors in immunity.The regulating function of heterotrimeric G proteins in the immune system.The value of experimental models of colitis in predicting efficacy of biological therapies for inflammatory bowel diseases.B cells with immune-regulating function in transplantation.Animal models of inflammatory bowel disease: a review.
P2860
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P2860
B cell developmental requirement for the G alpha i2 gene.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年学术文章
@wuu
2003年学术文章
@zh
2003年学术文章
@zh-cn
2003年学术文章
@zh-hans
2003年学术文章
@zh-my
2003年学术文章
@zh-sg
2003年學術文章
@yue
2003年學術文章
@zh-hant
name
B cell developmental requirement for the G alpha i2 gene.
@en
B cell developmental requirement for the G alpha i2 gene.
@nl
type
label
B cell developmental requirement for the G alpha i2 gene.
@en
B cell developmental requirement for the G alpha i2 gene.
@nl
prefLabel
B cell developmental requirement for the G alpha i2 gene.
@en
B cell developmental requirement for the G alpha i2 gene.
@nl
P2093
P1476
B cell developmental requirement for the G alpha i2 gene.
@en
P2093
David J Rawlings
Harnisha Dalwadi
Jonathan Braun
Karsten Spicher
Lutz Birnbaumer
Matthew Schrage
P304
P356
10.4049/JIMMUNOL.170.4.1707
P407
P577
2003-02-01T00:00:00Z