Coenzyme A biosynthesis: reconstruction of the pathway in archaea and an evolutionary scenario based on comparative genomics.
about
On the origin of biochemistry at an alkaline hydrothermal ventmetaSHARK: software for automated metabolic network prediction from DNA sequence and its application to the genomes of Plasmodium falciparum and Eimeria tenellaThe subsystems approach to genome annotation and its use in the project to annotate 1000 genomesStructure of the Type III Pantothenate Kinase from Bacillus anthracis at 2.0 Å Resolution: Implications for Coenzyme A-Dependent Redox Biology † , ‡Structure ofMycobacterium tuberculosisphosphopantetheine adenylyltransferase in complex with the feedback inhibitor CoA reveals only one active-site conformationDiscovery of Inhibitors of 4'-Phosphopantetheine Adenylyltransferase (PPAT) To Validate PPAT as a Target for Antibacterial TherapyCrystal structure of phosphopantothenate synthetase from Thermococcus kodakarensisCrystal structure of archaeal ketopantoate reductase complexed with coenzyme a and 2-oxopantoate provides structural insights into feedback regulationMolecular characterization of the heteromeric coenzyme A-synthesizing protein complex (CoA-SPC) in the yeast Saccharomyces cerevisiae.Characterization of a new pantothenate kinase isoform from Helicobacter pyloriEvolutionary diversification and characterization of the eubacterial gene family encoding DXR type II, an alternative isoprenoid biosynthetic enzymeBiological characterization of chemically diverse compounds targeting the Plasmodium falciparum coenzyme A synthesis pathwayA novel gene, ROA, is required for normal morphogenesis and discharge of ascospores in Gibberella zeaeDrosophila phosphopantothenoylcysteine synthetase is required for tissue morphogenesis during oogenesis.Avicinylation (thioesterification): a protein modification that can regulate the response to oxidative and nitrosative stress.Pantothenate kinase from the thermoacidophilic archaeon Picrophilus torridus.Provitamin B5 (pantothenol) inhibits growth of the intraerythrocytic malaria parasite.Characterization and kinetics of phosphopantothenoylcysteine synthetase from Enterococcus faecalis.Insights into the regulatory characteristics of the mycobacterial dephosphocoenzyme A kinase: implications for the universal CoA biosynthesis pathway.A global characterization and identification of multifunctional enzymes.Candidate phylum TM6 genome recovered from a hospital sink biofilm provides genomic insights into this uncultivated phylumPantoate kinase and phosphopantothenate synthetase, two novel enzymes necessary for CoA biosynthesis in the Archaea.Phylogenetic and amino acid conservation analyses of bacterial L-aspartate-α-decarboxylase and of its zymogen-maturation protein reveal a putative interaction domain.Identification and characterization of an archaeon-specific riboflavin kinaseVitamin and cofactor biosynthesis pathways in Plasmodium and other apicomplexan parasites.Biosynthesis of Pantothenic Acid and Coenzyme A.Uncovering metabolic pathways relevant to phenotypic traits of microbial genomes.Selective inhibitors of bacterial phosphopantothenoylcysteine synthetase.Validation of CoaBC as a Bactericidal Target in the Coenzyme A Pathway of Mycobacterium tuberculosis.Stereochemical modification of geminal dialkyl substituents on pantothenamides alters antimicrobial activityCoA biosynthesis in archaea.Biosynthesis of natural products containing β-amino acids.Recent advances in targeting coenzyme A biosynthesis and utilization for antimicrobial drug development.Exploiting the coenzyme A biosynthesis pathway for the identification of new antimalarial agents: the case for pantothenamides.An archaeal glutamate decarboxylase homolog functions as an aspartate decarboxylase and is involved in β-alanine and coenzyme A biosynthesis.Identification of a gene involved in the biosynthesis pathway of the terminal sugar of the archaellin N-linked tetrasaccharide in Methanococcus maripaludis.Regulation of Coenzyme A Biosynthesis in the Hyperthermophilic Bacterium Thermotoga maritima.The missing link in coenzyme A biosynthesis: PanM (formerly YhhK), a yeast GCN5 acetyltransferase homologue triggers aspartate decarboxylase (PanD) maturation in Salmonella entericaBiochemical characterization of pantoate kinase, a novel enzyme necessary for coenzyme A biosynthesis in the Archaea.A detailed biochemical characterization of phosphopantothenate synthetase, a novel enzyme involved in coenzyme A biosynthesis in the Archaea.
P2860
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P2860
Coenzyme A biosynthesis: reconstruction of the pathway in archaea and an evolutionary scenario based on comparative genomics.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年学术文章
@wuu
2004年学术文章
@zh
2004年学术文章
@zh-cn
2004年学术文章
@zh-hans
2004年学术文章
@zh-my
2004年学术文章
@zh-sg
2004年學術文章
@yue
2004年學術文章
@zh-hant
name
Coenzyme A biosynthesis: recon ...... based on comparative genomics.
@en
Coenzyme A biosynthesis: recon ...... based on comparative genomics.
@nl
type
label
Coenzyme A biosynthesis: recon ...... based on comparative genomics.
@en
Coenzyme A biosynthesis: recon ...... based on comparative genomics.
@nl
prefLabel
Coenzyme A biosynthesis: recon ...... based on comparative genomics.
@en
Coenzyme A biosynthesis: recon ...... based on comparative genomics.
@nl
P356
P1476
Coenzyme A biosynthesis: recon ...... based on comparative genomics.
@en
P2093
Ulrich Genschel
P304
P356
10.1093/MOLBEV/MSH119
P577
2004-03-10T00:00:00Z