Doxorubicin induces apoptosis in normal and tumor cells via distinctly different mechanisms. intermediacy of H(2)O(2)- and p53-dependent pathways.
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Chemotherapeutic sensitization of leptomycin B resistant lung cancer cells by pretreatment with doxorubicinHydroxyl radical mediates cisplatin-induced apoptosis in human hair follicle dermal papilla cells and keratinocytes through Bcl-2-dependent mechanismMitochondrial superoxide mediates doxorubicin-induced keratinocyte apoptosis through oxidative modification of ERK and Bcl-2 ubiquitinationFatty acid amide hydrolase is a key regulator of endocannabinoid-induced myocardial tissue injuryG-actin guides p53 nuclear transport: potential contribution of monomeric actin in altered localization of mutant p53.Molecular targets in urothelial cancer: detection, treatment, and animal models of bladder cancerCellular levels of oxidative stress affect the response of cervical cancer cells to chemotherapeutic agentsA switching mechanism in doxorubicin bioactivation can be exploited to control doxorubicin toxicityQuercetin potentiates doxorubicin mediated antitumor effects against liver cancer through p53/Bcl-xlAn increase in reactive oxygen species by deregulation of ARNT enhances chemotherapeutic drug-induced cancer cell deathSkeletal Muscle an Active Compartment in the Sequestering and Metabolism of Doxorubicin ChemotherapyNitric Oxide Down-Regulates Topoisomerase I and Induces Camptothecin Resistance in Human Breast MCF-7 Tumor CellsDoxorubicin activates nuclear factor of activated T-lymphocytes and Fas ligand transcription: role of mitochondrial reactive oxygen species and calciumExtracellular control of intracellular drug release for enhanced safety of anti-cancer chemotherapyDoxorubicin induces senescence or apoptosis in rat neonatal cardiomyocytes by regulating the expression levels of the telomere binding factors 1 and 2.Early detection of doxorubicin cardiomyopathy using two-dimensional strain echocardiography.Bioorthogonal cyclization-mediated in situ self-assembly of small-molecule probes for imaging caspase activity in vivoAdvantages and application of label-free detection assays in drug screening.ROS and protein oxidation in early stages of cytotoxic drug induced apoptosis.Homeodomain interacting protein kinase 2: a target for Alzheimer's beta amyloid leading to misfolded p53 and inappropriate cell survivalCinnamon extract induces tumor cell death through inhibition of NFkappaB and AP1Doxorubicin combined with celecoxib inhibits tumor growth of medullary thyroid carcinoma in xenografted miceBreast cancer stem cells rely on fermentative glycolysis and are sensitive to 2-deoxyglucose treatment.Doxorubicin, DNA torsion, and chromatin dynamics.Conformational altered p53 as an early marker of oxidative stress in Alzheimer's diseaseThe threonine protease activity of testes-specific protease 50 (TSP50) is essential for its function in cell proliferation.Anticancer drug-loaded multifunctional nanoparticles to enhance the chemotherapeutic efficacy in lung cancer metastasisThymol and Carvacrol Prevent Doxorubicin-Induced Cardiotoxicity by Abrogation of Oxidative Stress, Inflammation, and Apoptosis in Rats.Peroxiredoxin II restrains DNA damage-induced death in cancer cells by positively regulating JNK-dependent DNA repair.Assembled microcapsules by doxorubicin and polysaccharide as high effective anticancer drug carriers.Y-box binding protein 1 enhances DNA topoisomerase 1 activity and sensitivity to camptothecin via direct interaction.Glutathione peroxidase-1 in health and disease: from molecular mechanisms to therapeutic opportunitiestLivin displays flexibility by promoting alternative cell death mechanismsA Novobiocin Derivative, XN4, Inhibits the Proliferation of Chronic Myeloid Leukemia Cells by Inducing Oxidative DNA DamageManganese (III) meso-tetrakis N-ethylpyridinium-2-yl porphyrin acts as a pro-oxidant to inhibit electron transport chain proteins, modulate bioenergetics, and enhance the response to chemotherapy in lymphoma cells.Requirement of transmembrane transport for S-nitrosocysteine-dependent modification of intracellular thiols.Members of the glutathione and ABC-transporter families are associated with clinical outcome in patients with diffuse large B-cell lymphoma.Synergistic antitumor activity of camptothecin-doxorubicin combinations and their conjugates with hyaluronic acid.MicroRNA-208a Silencing Attenuates Doxorubicin Induced Myocyte Apoptosis and Cardiac Dysfunction.Combinatorial synthesis and screening of cancer cell-specific nanomedicines targeted via phage fusion proteins.
P2860
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P2860
Doxorubicin induces apoptosis in normal and tumor cells via distinctly different mechanisms. intermediacy of H(2)O(2)- and p53-dependent pathways.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年学术文章
@wuu
2004年学术文章
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2004年学术文章
@zh-cn
2004年学术文章
@zh-hans
2004年学术文章
@zh-my
2004年学术文章
@zh-sg
2004年學術文章
@yue
2004年學術文章
@zh-hant
name
Doxorubicin induces apoptosis ...... mechanisms. intermediacy of H
@nl
Doxorubicin induces apoptosis ...... )- and p53-dependent pathways.
@en
type
label
Doxorubicin induces apoptosis ...... mechanisms. intermediacy of H
@nl
Doxorubicin induces apoptosis ...... )- and p53-dependent pathways.
@en
prefLabel
Doxorubicin induces apoptosis ...... mechanisms. intermediacy of H
@nl
Doxorubicin induces apoptosis ...... )- and p53-dependent pathways.
@en
P2093
P2860
P356
P1476
Doxorubicin induces apoptosis ...... )- and p53-dependent pathways.
@en
P2093
B Kalyanaraman
Eugene A Konorev
Joy Joseph
Shasi Kalivendi
Srigiridhar Kotamraju
Suwei Wang
P2860
P304
25535-25543
P356
10.1074/JBC.M400944200
P407
P577
2004-03-30T00:00:00Z