Carbonic anhydrase inhibitors. Design of selective, membrane-impermeant inhibitors targeting the human tumor-associated isozyme IX.
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The structural comparison between membrane-associated human carbonic anhydrases provides insights into drug design of selective inhibitorsExpression of carbonic anhydrases IX and XII during mouse embryonic developmentSaccharin: a lead compound for structure-based drug design of carbonic anhydrase IX inhibitors.Synthesis of N-arylpyridinium salts bearing a nitrone spin trap as potential mitochondria-targeted antioxidants.Sulfonamides: a patent review (2008 - 2012).Update on carbonic anhydrase inhibitors: a patent review (2008 - 2011).Thiadiazole-a promising structure in medicinal chemistry.Anticancer carbonic anhydrase inhibitors: a patent review (2008 - 2013).Carbonic anhydrase IX as an imaging and therapeutic target for tumors and metastases.Sulfonamides and their isosters as carbonic anhydrase inhibitors.Targeting carbonic anhydrase IX activity and expression.Drug interaction considerations in the therapeutic use of carbonic anhydrase inhibitors.Cancer-associated, hypoxia-inducible carbonic anhydrase IX facilitates CO2 diffusion.Carbonic anhydrase inhibitors that directly inhibit anion transport by the human Cl-/HCO3- exchanger, AE1.Epithelial carbonic anhydrases facilitate PCO2 and pH regulation in rat duodenal mucosa.Novel antibody to a carbonic anhydrase: patent evaluation of WO2011138279A1.Discovery of Strecker-type α-aminonitriles as a new class of human carbonic anhydrase inhibitors using differential scanning fluorimetry.Both NKCC1 and anion exchangers contribute to Cl⁻ accumulation in postnatal forebrain neuronal progenitors.Extra- and intracellular unstirred layer effects in measurements of CO2 diffusion across membranes--a novel approach applied to the mass spectrometric 18O technique for red blood cells.Design, synthesis and evaluation of 18F-labeled cationic carbonic anhydrase IX inhibitors for PET imaging.Discovery of novel 1,3-diaryltriazene sulfonamides as carbonic anhydrase I, II, VII, and IX inhibitorsAssessment of the antiproliferative and apoptotic roles of sulfonamide carbonic anhydrase IX inhibitors in HeLa cancer cell lineTarget-based drug discovery through inversion of quantitative structure-drug-property relationships and molecular simulation: CA IX-sulphonamide complexesPyridinium derivatives of histamine are potent activators of cytosolic carbonic anhydrase isoforms I, II and VIICarbonic anhydrase inhibitors and activators and their use in therapyCarbonic anhydrase inhibitors. Inhibition of human tumor-associated isozymes IX and cytosolic isozymes I and II with some 1,3,4-oxadiazole-thiolsCarbonic anhydrase inhibitors. Selective inhibition of human tumor-associated isozymes IX and XII and cytosolic isozymes I and II with some substituted-2-mercapto-benzenesulfonamides
P2860
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P2860
Carbonic anhydrase inhibitors. Design of selective, membrane-impermeant inhibitors targeting the human tumor-associated isozyme IX.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年学术文章
@wuu
2004年学术文章
@zh
2004年学术文章
@zh-cn
2004年学术文章
@zh-hans
2004年学术文章
@zh-my
2004年学术文章
@zh-sg
2004年學術文章
@yue
2004年學術文章
@zh-hant
name
Carbonic anhydrase inhibitors. ...... n tumor-associated isozyme IX.
@en
Carbonic anhydrase inhibitors. ...... n tumor-associated isozyme IX.
@nl
type
label
Carbonic anhydrase inhibitors. ...... n tumor-associated isozyme IX.
@en
Carbonic anhydrase inhibitors. ...... n tumor-associated isozyme IX.
@nl
prefLabel
Carbonic anhydrase inhibitors. ...... n tumor-associated isozyme IX.
@en
Carbonic anhydrase inhibitors. ...... n tumor-associated isozyme IX.
@nl
P2093
P50
P356
P1476
Carbonic anhydrase inhibitors. ...... n tumor-associated isozyme IX.
@en
P2093
Antonio Mastrolorenzo
Claudiu T Supuran
Daniela Vullo
P304
P356
10.1021/JM031079W
P407
P577
2004-04-01T00:00:00Z