Luminal flow induces eNOS activation and translocation in the rat thick ascending limb. II. Role of PI3-kinase and Hsp90.
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Tumor necrosis factor α decreases nitric oxide synthase type 3 expression primarily via Rho/Rho kinase in the thick ascending limbAngiotensin II stimulates thick ascending limb NO production via AT(2) receptors and Akt1-dependent nitric-oxide synthase 3 (NOS3) activationIntratubular hydrodynamic forces influence tubulointerstitial fibrosis in the kidney.Shear stress increases nitric oxide production in thick ascending limbs.Luminal flow regulates NO and O2(-) along the nephronAngiotensin II-induced hypertension blunts thick ascending limb NO production by reducing NO synthase 3 expression and enhancing threonine 495 phosphorylation.Endogenous flow-induced nitric oxide reduces superoxide-stimulated Na/H exchange activity via PKG in thick ascending limbsSubcellular targeting and trafficking of nitric oxide synthases.Angiotensin II stimulates superoxide production by nitric oxide synthase in thick ascending limbs.Nitric oxide reduces flow-induced superoxide production via cGMP-dependent protein kinase in thick ascending limbs.Angiotensin II decreases nitric oxide synthase 3 expression via nitric oxide and superoxide in the thick ascending limbAkt1 mediates purinergic-dependent NOS3 activation in thick ascending limbs.In vivo and ex vivo analysis of tubule function.Chemical and Physical Sensors in the Regulation of Renal Function.Role of the Primary Cilia on the Macula Densa and Thick Ascending Limbs in Regulation of Sodium Excretion and Hemodynamics.Endothelin-1 inhibits thick ascending limb transport via Akt-stimulated nitric oxide production.Fluid shear stress induces renal epithelial gene expression through polycystin-2-dependent trafficking of extracellular regulated kinase.
P2860
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P2860
Luminal flow induces eNOS activation and translocation in the rat thick ascending limb. II. Role of PI3-kinase and Hsp90.
description
2004 nî lūn-bûn
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2004年の論文
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2004年学术文章
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2004年学术文章
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2004年学术文章
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2004年学术文章
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name
Luminal flow induces eNOS acti ...... Role of PI3-kinase and Hsp90.
@en
Luminal flow induces eNOS acti ...... Role of PI3-kinase and Hsp90.
@nl
type
label
Luminal flow induces eNOS acti ...... Role of PI3-kinase and Hsp90.
@en
Luminal flow induces eNOS acti ...... Role of PI3-kinase and Hsp90.
@nl
prefLabel
Luminal flow induces eNOS acti ...... Role of PI3-kinase and Hsp90.
@en
Luminal flow induces eNOS acti ...... Role of PI3-kinase and Hsp90.
@nl
P2093
P2860
P1476
Luminal flow induces eNOS acti ...... Role of PI3-kinase and Hsp90.
@en
P2093
Jeffrey L Garvin
Nancy J Hong
Pablo A Ortiz
P2860
P304
P356
10.1152/AJPRENAL.00383.2003
P577
2004-04-20T00:00:00Z