The zinc finger repressor, ZBP-89, binds to the silencer element of the human vimentin gene and complexes with the transcriptional activator, Sp1.
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ZBP-89 represses vimentin gene transcription by interacting with the transcriptional activator, Sp1Twenty-one-base-pair insertion polymorphism creates an enhancer element and potentiates SLC6A1 GABA transporter promoter activityTranscription factor ZBP-89 cooperates with histone acetyltransferase p300 during butyrate activation of p21waf1 transcription in human cellsStat3 enhances vimentin gene expression by binding to the antisilencer element and interacting with the repressor protein, ZBP-89Over-expression of the transcription factor, ZBP-89, leads to enhancement of the C2C12 myogenic program.The leukocyte integrin gene CD11d is repressed by gut-enriched Kruppel-like factor 4 in myeloid cells.Vimentin in cancer and its potential as a molecular target for cancer therapy.Role of ZBP-89 in human globin gene regulation and erythroid differentiationThyroid transcription factor-1 (TTF-1) gene: identification of ZBP-89, Sp1, and TTF-1 sites in the promoter and regulation by TNF-α in lung epithelial cellsA PDGFRA promoter polymorphism, which disrupts the binding of ZNF148, is associated with primitive neuroectodermal tumours and ependymomas.TGFbeta1 regulation of vimentin gene expression during differentiation of the C2C12 skeletal myogenic cell line requires Smads, AP-1 and Sp1 family members.The transcriptional repressor ZBP-89 and the lack of Sp1/Sp3, c-Jun and Stat3 are important for the down-regulation of the vimentin gene during C2C12 myogenesis.Methods for proteomic analysis of transcription factors.Molecular characterization of the constitutive expression of the plasma platelet-activating factor acetylhydrolase gene in macrophages.Palmitate increases Nur77 expression by modulating ZBP89 and Sp1 binding to the Nur77 proximal promoter in pancreatic β-cells.Sumoylation-dependent control of homotypic and heterotypic synergy by the Kruppel-type zinc finger protein ZBP-89.Retinoic acid activates human secretin gene expression by Sp proteins and nuclear factor I in neuronal SH-SY5Y cells.The dominant role of Sp1 in regulating the cystathionine beta-synthase -1a and -1b promoters facilitates potential tissue-specific regulation by Kruppel-like factors.c-Jun and the dominant-negative mutant, TAM67, induce vimentin gene expression by interacting with the activator Sp1.The Epstein-Barr virus protein BMRF1 activates gastrin transcription.Identification and characterization of a transcriptional regulator for the lck proximal promoter.Characterization of a functional ZBP-89 binding site that mediates Gata1 gene expression during hematopoietic development.ZBP-89, Sp1, and nuclear factor-kappa B regulate epithelial neutrophil-activating peptide-78 gene expression in Caco-2 human colonic epithelial cells.The zinc finger repressor, ZBP-89, recruits histone deacetylase 1 to repress vimentin gene expression.ZBP-89 function in colonic stem cells and during butyrate-induced senescence.Zinc-finger proteins in health and disease.Modulating the expression of Chtop, a versatile regulator of gene-specific transcription and mRNA export.ZBP-89 and Sp1 contribute to Bak expression in hepatocellular carcinoma cells.
P2860
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P2860
The zinc finger repressor, ZBP-89, binds to the silencer element of the human vimentin gene and complexes with the transcriptional activator, Sp1.
description
2000 nî lūn-bûn
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2000年の論文
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2000年学术文章
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2000年学术文章
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2000年学术文章
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2000年学术文章
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2000年学术文章
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name
The zinc finger repressor, ZBP ...... ranscriptional activator, Sp1.
@en
The zinc finger repressor, ZBP ...... ranscriptional activator, Sp1.
@nl
type
label
The zinc finger repressor, ZBP ...... ranscriptional activator, Sp1.
@en
The zinc finger repressor, ZBP ...... ranscriptional activator, Sp1.
@nl
prefLabel
The zinc finger repressor, ZBP ...... ranscriptional activator, Sp1.
@en
The zinc finger repressor, ZBP ...... ranscriptional activator, Sp1.
@nl
P2093
P2860
P356
P1476
The zinc finger repressor, ZBP ...... ranscriptional activator, Sp1.
@en
P2093
P2860
P304
12879-12888
P356
10.1074/JBC.275.17.12879
P407
P577
2000-04-01T00:00:00Z