Human deafness mutation of myosin VI (C442Y) accelerates the ADP dissociation rate.
about
A unique ATP hydrolysis mechanism of single-headed processive myosin, myosin IXThe effect of novel mutations on the structure and enzymatic activity of unconventional myosins associated with autosomal dominant non-syndromic hearing loss.Activated full-length myosin-X moves processively on filopodia with large steps toward diverse two-dimensional directionsReverse conformational changes of the light chain-binding domain of myosin V and VI processive motor heads during and after hydrolysis of ATP by small-angle X-ray solution scatteringMyosin VI deafness mutation prevents the initiation of processive runs on actinMechanism of action of myosin X, a membrane-associated molecular motor.Loss of cargo binding in the human myosin VI deafness mutant (R1166X) leads to increased actin filament bindingKinetic properties and small-molecule inhibition of human myosin-6.Loss of myosin VI no insert isoform (NoI) induces a defect in clathrin-mediated endocytosis and leads to caveolar endocytosis of transferrin receptor.Kinematics of the lever arm swing in myosin VI.
P2860
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P2860
Human deafness mutation of myosin VI (C442Y) accelerates the ADP dissociation rate.
description
2004 nî lūn-bûn
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2004年の論文
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2004年学术文章
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name
Human deafness mutation of myosin VI (C442Y) accelerates the ADP dissociation rate.
@en
Human deafness mutation of myosin VI
@nl
type
label
Human deafness mutation of myosin VI (C442Y) accelerates the ADP dissociation rate.
@en
Human deafness mutation of myosin VI
@nl
prefLabel
Human deafness mutation of myosin VI (C442Y) accelerates the ADP dissociation rate.
@en
Human deafness mutation of myosin VI
@nl
P2093
P2860
P356
P1476
Human deafness mutation of myosin VI (C442Y) accelerates the ADP dissociation rate.
@en
P2093
Akira Inoue
Betty Belknap
Howard D White
Mitsuo Ikebe
Osamu Sato
Reiko Ikebe
P2860
P304
28844-28854
P356
10.1074/JBC.M314332200
P407
P577
2004-04-29T00:00:00Z