The Drosophila double-timeS mutation delays the nuclear accumulation of period protein and affects the feedback regulation of period mRNA.
about
Activating PER repressor through a DBT-directed phosphorylation switchDrosophila doubletime mutations which either shorten or lengthen the period of circadian rhythms decrease the protein kinase activity of casein kinase IKinetics of doubletime kinase-dependent degradation of the Drosophila period protein.Drosophila and vertebrate casein kinase Idelta exhibits evolutionary conservation of circadian functionDifferential effects of PER2 phosphorylation: molecular basis for the human familial advanced sleep phase syndrome (FASPS)A small conserved domain of Drosophila PERIOD is important for circadian phosphorylation, nuclear localization, and transcriptional repressor activityDrosophila DBT lacking protein kinase activity produces long-period and arrhythmic circadian behavioral and molecular rhythmsNoncanonical FK506-binding protein BDBT binds DBT to enhance its circadian function and forms foci at night.CK2 phosphorylation of CCA1 is necessary for its circadian oscillator function in Arabidopsis.Dominant-negative CK2alpha induces potent effects on circadian rhythmicityCircadian transcription contributes to core period determination in Drosophila.PDF neuron firing phase-shifts key circadian activity neurons in DrosophilaA reduced model clarifies the role of feedback loops and time delays in the Drosophila circadian oscillatorSimulation of Drosophila circadian oscillations, mutations, and light responses by a model with VRI, PDP-1, and CLK.A hierarchical phosphorylation cascade that regulates the timing of PERIOD nuclear entry reveals novel roles for proline-directed kinases and GSK-3beta/SGG in circadian clocks.A role for timely nuclear translocation of clock repressor proteins in setting circadian clock speedSpeed control: cogs and gears that drive the circadian clock.Of switches and hourglasses: regulation of subcellular traffic in circadian clocks by phosphorylation.Drosophila DBT Autophosphorylation of Its C-Terminal Domain Antagonized by SPAG and Involved in UV-Induced ApoptosisA Doubletime Nuclear Localization Signal Mediates an Interaction with Bride of Doubletime to Promote Circadian Function.A key temporal delay in the circadian cycle of Drosophila is mediated by a nuclear localization signal in the timeless protein.A proposal for robust temperature compensation of circadian rhythms.A role for O-GlcNAcylation in setting circadian clock speedA DOUBLETIME kinase binding domain on the Drosophila PERIOD protein is essential for its hyperphosphorylation, transcriptional repression, and circadian clock function.Temperature compensation and temperature sensation in the circadian clock.c-Jun N-terminal kinase inhibitor SP600125 modulates the period of mammalian circadian rhythms.Internal noise-sustained circadian rhythms in a Drosophila model.Probing the relative importance of molecular oscillations in the circadian clock.Post-translational modifications in circadian rhythmsCircadian Rhythms and Sleep in Drosophila melanogaster.The MAP kinase p38 is part of Drosophila melanogaster's circadian clock.Casein kinase 1 promotes synchrony of the circadian clock network.The double-time protein kinase regulates the subcellular localization of the Drosophila clock protein periodPost-translational regulation and nuclear entry of TIMELESS and PERIOD are affected in new timeless mutant.CK1/Doubletime activity delays transcription activation in the circadian clock.
P2860
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P2860
The Drosophila double-timeS mutation delays the nuclear accumulation of period protein and affects the feedback regulation of period mRNA.
description
2001 nî lūn-bûn
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2001年の論文
@ja
2001年学术文章
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2001年学术文章
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2001年学术文章
@zh-hans
2001年学术文章
@zh-my
2001年学术文章
@zh-sg
2001年學術文章
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2001年學術文章
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2001年學術文章
@zh-hant
name
The Drosophila double-timeS mu ...... ack regulation of period mRNA.
@en
The Drosophila double-timeS mu ...... ack regulation of period mRNA.
@nl
type
label
The Drosophila double-timeS mu ...... ack regulation of period mRNA.
@en
The Drosophila double-timeS mu ...... ack regulation of period mRNA.
@nl
prefLabel
The Drosophila double-timeS mu ...... ack regulation of period mRNA.
@en
The Drosophila double-timeS mu ...... ack regulation of period mRNA.
@nl
P2093
P1476
The Drosophila double-timeS mu ...... back regulation of period mRNA
@en
P2093
P304
P356
10.1523/JNEUROSCI.21-18-07117.2001
P407
P577
2001-09-01T00:00:00Z