Population pharmacokinetic/pharmacodynamic modeling to assist dosing schedule selection for dovitinib.
about
Phase II study of dovitinib in patients with metastatic and/or unresectable gastrointestinal stromal tumours after failure of imatinib and sunitinib.The anticancer multi-kinase inhibitor dovitinib also targets topoisomerase I and topoisomerase II.A Receptor Tyrosine Kinase Inhibitor, Dovitinib (TKI-258), Enhances BMP-2-Induced Osteoblast Differentiation In Vitro.Dovitinib versus sorafenib for third-line targeted treatment of patients with metastatic renal cell carcinoma: an open-label, randomised phase 3 trial.Targeting fibroblast growth factor receptor in breast cancer: a promise or a pitfall?Pharmacokinetic Aspects of Vascular Endothelial Growth Factor Tyrosine Kinase Inhibitors.Dovitinib (CHIR258, TKI258): structure, development and preclinical and clinical activity.Population pharmacokinetics of mycophenolic acid and its glucuronide metabolite in lung transplant recipients with and without cystic fibrosis.Interaction potential of the multitargeted receptor tyrosine kinase inhibitor dovitinib with drug transporters and drug metabolising enzymes assessed in vitro.The effect of formulation and food consumption on the bioavailability of dovitinib (TKI258) in patients with advanced solid tumors.Population pharmacokinetic and pharmacodynamic modeling of different formulations of ONO-5334, cathepsin K inhibitor, in Caucasian and Japanese postmenopausal females.Phase 2 study of dovitinib in patients with metastatic or unresectable adenoid cystic carcinoma.A randomized, crossover phase 1 study to assess the effects of formulation (capsule vs tablet) and meal consumption on the bioavailability of dovitinib (TKI258).
P2860
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P2860
Population pharmacokinetic/pharmacodynamic modeling to assist dosing schedule selection for dovitinib.
description
2013 nî lūn-bûn
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2013年の論文
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2013年学术文章
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2013年学术文章
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2013年学术文章
@zh-hans
2013年学术文章
@zh-my
2013年学术文章
@zh-sg
2013年學術文章
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2013年學術文章
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2013年學術文章
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name
Population pharmacokinetic/pha ...... edule selection for dovitinib.
@en
Population pharmacokinetic/pha ...... edule selection for dovitinib.
@nl
type
label
Population pharmacokinetic/pha ...... edule selection for dovitinib.
@en
Population pharmacokinetic/pha ...... edule selection for dovitinib.
@nl
prefLabel
Population pharmacokinetic/pha ...... edule selection for dovitinib.
@en
Population pharmacokinetic/pha ...... edule selection for dovitinib.
@nl
P2093
P2860
P356
P1476
Population pharmacokinetic/pha ...... edule selection for dovitinib.
@en
P2093
Andrea Kay
Horst Schran
Margaret Dugan
Oezlem Anak
Xiaofeng Wang
Yilin Feng
P2860
P356
10.1177/0091270011433330
P577
2013-01-24T00:00:00Z