Modelling cardiac calcium sparks in a three-dimensional reconstruction of a calcium release unit.
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Calcium and IP3 dynamics in cardiac myocytes: experimental and computational perspectives and approachesCalcium movements inside the sarcoplasmic reticulum of cardiac myocytesPernicious attrition and inter-RyR2 CICR current control in cardiac muscleAlterations in T-tubule and dyad structure in heart disease: challenges and opportunities for computational analysesAn integrated finite element simulation of cardiomyocyte function based on triphasic theoryExamination of the Effects of Heterogeneous Organization of RyR Clusters, Myofibrils and Mitochondria on Ca2+ Release Patterns in CardiomyocytesModeling effects of L-type ca(2+) current and na(+)-ca(2+) exchanger on ca(2+) trigger flux in rabbit myocytes with realistic T-tubule geometriesA multiscale computational model of spatially resolved calcium cycling in cardiac myocytes: from detailed cleft dynamics to the whole cell concentration profiles.Computational modeling of subcellular transport and signaling.Store-dependent deactivation: cooling the chain-reaction of myocardial calcium signaling.Nonlinear and Stochastic Dynamics in the HeartFinite Element Estimation of Protein-Ligand Association Rates with Post-Encounter Effects: Applications to Calcium binding in Troponin C and SERCA.Extraction of sub-microscopic Ca fluxes from blurred and noisy fluorescent indicator images with a detailed model fitting approachSuperresolution modeling of calcium release in the heartThe ryanodine receptor patchwork: knitting calcium spark dynamics.T-tubule disruption promotes calcium alternans in failing ventricular myocytes: mechanistic insights from computational modelingLong-Lasting Sparks: Multi-Metastability and Release Competition in the Calcium Release Unit NetworkElectron tomography of rabbit cardiomyocyte three-dimensional ultrastructure.Enzyme localization, crowding, and buffers collectively modulate diffusion-influenced signal transduction: Insights from continuum diffusion modeling.Ultrastructural Analysis of Self-Associated RyR2sA Computational Modeling and Simulation Approach to Investigate Mechanisms of Subcellular cAMP Compartmentation.Calcium Dynamics of Ex Vivo Long-Term Cultured CD8+ T Cells Are Regulated by Changes in Redox Metabolism.Hierarchical approaches for systems modeling in cardiac development.Influence of neighboring reactive particles on diffusion-limited reactions.Sensitivity of rabbit ventricular action potential and Ca²⁺ dynamics to small variations in membrane currents and ion diffusion coefficients.Molecular and subcellular-scale modeling of nucleotide diffusion in the cardiac myofilament lattice.Mechanotransduction and Metabolism in Cardiomyocyte Microdomains.A model study of sequential enzyme reactions and electrostatic channeling.Decoding myocardial Ca²⁺ signals across multiple spatial scales: a role for sensitivity analysis.Regulation of RYR2 by sarcoplasmic reticulum Ca(2+).Modeling calcium regulation of contraction, energetics, signaling, and transcription in the cardiac myocyte.Studying dyadic structure-function relationships: a review of current modeling approaches and new insights into Ca2+ (mis)handling.Multi-scale Modeling of the Cardiovascular System: Disease Development, Progression, and Clinical Intervention.Modeling Na+-Ca2+ exchange in the heart: Allosteric activation, spatial localization, sparks and excitation-contraction coupling.The emergence of subcellular pacemaker sites for calcium waves and oscillations.Evoked centripetal Ca(2+) mobilization in cardiac Purkinje cells: insight from a model of three Ca(2+) release regions.Ambiguous interactions between diastolic and SR Ca2+ in the regulation of cardiac Ca2+ release.Towards simulation of subcellular calcium dynamics at nanometre resolutionThe Subcellular Distribution of Ryanodine Receptors and L-Type Ca Channels Modulates Ca-Transient Properties and Spontaneous Ca-Release Events in Atrial CardiomyocytesCalcium-Mediated Oscillation in Membrane Potentials and Atrial-Triggered Activity in Atrial Cells of Casq2 Mutation Mice
P2860
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P2860
Modelling cardiac calcium sparks in a three-dimensional reconstruction of a calcium release unit.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
@zh
2012年學術文章
@zh-hant
name
Modelling cardiac calcium spar ...... ion of a calcium release unit.
@en
Modelling cardiac calcium spar ...... ion of a calcium release unit.
@nl
type
label
Modelling cardiac calcium spar ...... ion of a calcium release unit.
@en
Modelling cardiac calcium spar ...... ion of a calcium release unit.
@nl
prefLabel
Modelling cardiac calcium spar ...... ion of a calcium release unit.
@en
Modelling cardiac calcium spar ...... ion of a calcium release unit.
@nl
P2093
P2860
P1476
Modelling cardiac calcium spar ...... ion of a calcium release unit.
@en
P2093
Andrew D McCulloch
Andrew G Edwards
Anushka P Michailova
Johan Hake
Masahiko Hoshijima
Michael J Holst
Peter M Kekenes-Huskey
P2860
P304
P356
10.1113/JPHYSIOL.2012.227926
P407
P577
2012-04-10T00:00:00Z