Tumor suppressor BRCA1 inhibits a breast cancer-associated promoter of the aromatase gene (CYP19) in human adipose stromal cells.
about
Modulation of in situ estrogen synthesis by proline-, glutamic acid-, and leucine-rich protein-1: potential estrogen receptor autocrine signaling loop in breast cancer cellsMechanical phenotype is important for stromal aromatase expression.Cell density-dependent transcriptional activation of endocrine-related genes in human adipose tissue-derived stem cellsCell density is a critical determinant of aromatase expression in adipose stromal cells.Interleukin 6 secreted from adipose stromal cells promotes migration and invasion of breast cancer cells.ERalpha-negative and triple negative breast cancer: molecular features and potential therapeutic approachesGerosuppressant metformin: less is moreAromatase expression increases the survival and malignancy of estrogen receptor positive breast cancer cellsOpposing roles for mammary epithelial-specific PPARγ signaling and activation during breast tumour progressionDNA stabilization by the upregulation of estrogen signaling in BRCA gene mutation carriers.Alterations in Brca1 expression in mouse ovarian granulosa cells have short-term and long-term consequences on estrogen-responsive organs.CyTRANSFINDER: a Cytoscape 3.3 plugin for three-component (TF, gene, miRNA) signal transduction pathway construction.PPARγ agonists target aromatase via both PGE2 and BRCA1.Pioglitazone, a PPARγ agonist, suppresses CYP19 transcription: evidence for involvement of 15-hydroxyprostaglandin dehydrogenase and BRCA1.BRCA1, hormone, and tissue-specific tumor suppressionEndocrinology of the wild and mutant BRCA1 gene and types of hormonal carcinogenesis.Aromatase expression is increased in BRCA1 mutation carriers.A Role of CREB in BRCA1 Constitutive Promoter Activity and Aromatase Basal Expression.Abnormal Mammary Adipose Tissue Environment of Brca1 Mutant Mice Show a Persistent Deposition of Highly Vascularized Multilocular Adipocytes.Polymorphisms in DNA repair pathway genes, body mass index, and risk of non-Hodgkin lymphoma.PARP inhibitors: review of mechanisms of action and BRCA1/2 mutation targeting.EP2 and EP4 receptors regulate aromatase expression in human adipocytes and breast cancer cells. Evidence of a BRCA1 and p300 exchange.Stromal adipocyte PPARγ protects against breast tumorigenesis.Molecular insights into the association of obesity with breast cancer risk: relevance to xenobiotic metabolism and CpG island methylation of tumor suppressor genes.
P2860
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P2860
Tumor suppressor BRCA1 inhibits a breast cancer-associated promoter of the aromatase gene (CYP19) in human adipose stromal cells.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年学术文章
@wuu
2006年学术文章
@zh-cn
2006年学术文章
@zh-hans
2006年学术文章
@zh-my
2006年学术文章
@zh-sg
2006年學術文章
@yue
2006年學術文章
@zh
2006年學術文章
@zh-hant
name
Tumor suppressor BRCA1 inhibit ...... n human adipose stromal cells.
@en
Tumor suppressor BRCA1 inhibits a breast cancer-associated promoter of the aromatase gene
@nl
type
label
Tumor suppressor BRCA1 inhibit ...... n human adipose stromal cells.
@en
Tumor suppressor BRCA1 inhibits a breast cancer-associated promoter of the aromatase gene
@nl
prefLabel
Tumor suppressor BRCA1 inhibit ...... n human adipose stromal cells.
@en
Tumor suppressor BRCA1 inhibits a breast cancer-associated promoter of the aromatase gene
@nl
P2093
P2860
P1476
Tumor suppressor BRCA1 inhibit ...... in human adipose stromal cells
@en
P2093
P2860
P304
P356
10.1152/AJPENDO.00242.2006
P50
P577
2006-08-29T00:00:00Z