Cyclic GMP-dependent protein kinase Ialpha attenuates necrosis and apoptosis following ischemia/reoxygenation in adult cardiomyocyte.
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Triggers, inhibitors, mechanisms, and significance of eryptosis: the suicidal erythrocyte deathMitogen-activated protein kinase signaling in the heart: angels versus demons in a heart-breaking tale.Scutellarin's Cardiovascular Endothelium Protective Mechanism: Important Role of PKG-IαAnalysis of p53 and NF-κB signaling in modulating the cardiomyocyte fate during hypertrophyChronic inhibition of phosphodiesterase 5 with tadalafil attenuates mitochondrial dysfunction in type 2 diabetic hearts: potential role of NO/SIRT1/PGC-1α signaling.Guanylyl cyclase-G modulates jejunal apoptosis and inflammation in mice with intestinal ischemia and reperfusionInduction of microRNA-21 with exogenous hydrogen sulfide attenuates myocardial ischemic and inflammatory injury in miceAberrant dynamin 2-dependent Na(+) /H(+) exchanger-1 trafficking contributes to cardiomyocyte apoptosis.Phosphodiesterase-5 inhibition mimics intermittent reoxygenation and improves cardioprotection in the hypoxic myocardium.Long-acting phosphodiesterase-5 inhibitor tadalafil attenuates doxorubicin-induced cardiomyopathy without interfering with chemotherapeutic effect.cGMP increases antioxidant function and attenuates oxidant cell death in mouse lung microvascular endothelial cells by a protein kinase G-dependent mechanismCyclic guanosine monophosphate signaling and phosphodiesterase-5 inhibitors in cardioprotection.Phosphodiesterase inhibition with tadalafil provides longer and sustained protection of stem cells.Phosphodiesterase-5 inhibitor, tadalafil, protects against myocardial ischemia/reperfusion through protein-kinase g-dependent generation of hydrogen sulfideSildenafil and vardenafil but not nitroglycerin limit myocardial infarction through opening of mitochondrial K(ATP) channels when administered at reperfusion following ischemia in rabbitsInhibition of JNK aggravates the recovery of rat hearts after global ischemia: the role of mitochondrial JNK.Protein kinase G1 α overexpression increases stem cell survival and cardiac function after myocardial infarction.Mitigation of the progression of heart failure with sildenafil involves inhibition of RhoA/Rho-kinase pathwayERK/PP1a/PLB/SERCA2a and JNK pathways are involved in luteolin-mediated protection of rat hearts and cardiomyocytes following ischemia/reperfusion.Tadalafil, a Phosphodiesterase Inhibitor Protects Stem Cells over Longer Period Against Hypoxia/Reoxygenation Injury Through STAT3/PKG-I Signaling.In Vivo Protective Effects of Diosgenin against Doxorubicin-Induced Cardiotoxicity.PDE5 inhibitors as therapeutics for heart disease, diabetes and cancerOverexpression of cGMP-dependent protein kinase I (PKG-I) attenuates ischemia-reperfusion-induced kidney injury.Cardiac role of cyclic-GMP hydrolyzing phosphodiesterase type 5: from experimental models to clinical trials.Cyclic GMP and protein kinase-G in myocardial ischaemia-reperfusion: opportunities and obstacles for survival signaling.Cardiovascular protection with sildenafil following chronic inhibition of nitric oxide synthase.Anemia and splenomegaly in cGKI-deficient mice.Myocardial AKT: the omnipresent nexus.Long-acting phosphodiesterase-5 inhibitor, tadalafil, induces sustained cardioprotection against lethal ischemic injury.Cyclic GMP signaling in cardiovascular pathophysiology and therapeutics.Protein kinase G increases antioxidant function in lung microvascular endothelial cells by inhibiting the c-Abl tyrosine kinase.Cyclic GMP signaling in cardiomyocytes modulates fatty acid trafficking and prevents triglyceride accumulationEmerging tools for erectile dysfunction: a role for regenerative medicine.Everything you ever wanted to know about phosphodiesterase 5 inhibitors and the heart (but never dared ask): How do they work?Beet root juice protects against doxorubicin toxicity in cardiomyocytes while enhancing apoptosis in breast cancer cells.The CO/HO system reverses inhibition of mitochondrial biogenesis and prevents murine doxorubicin cardiomyopathy.Hydrogen sulfide mediates the cardioprotective effects of gene therapy with PKG-Iα.Protein kinase G-dependent cardioprotective mechanism of phosphodiesterase-5 inhibition involves phosphorylation of ERK and GSK3beta.Protein kinase g iα inhibits pressure overload-induced cardiac remodeling and is required for the cardioprotective effect of sildenafil in vivo.Pharmacological postconditioning by bolus injection of phosphodiesterase-5 inhibitors vardenafil and sildenafil.
P2860
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P2860
Cyclic GMP-dependent protein kinase Ialpha attenuates necrosis and apoptosis following ischemia/reoxygenation in adult cardiomyocyte.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年学术文章
@wuu
2006年学术文章
@zh-cn
2006年学术文章
@zh-hans
2006年学术文章
@zh-my
2006年学术文章
@zh-sg
2006年學術文章
@yue
2006年學術文章
@zh
2006年學術文章
@zh-hant
name
Cyclic GMP-dependent protein k ...... nation in adult cardiomyocyte.
@en
Cyclic GMP-dependent protein k ...... nation in adult cardiomyocyte.
@nl
type
label
Cyclic GMP-dependent protein k ...... nation in adult cardiomyocyte.
@en
Cyclic GMP-dependent protein k ...... nation in adult cardiomyocyte.
@nl
prefLabel
Cyclic GMP-dependent protein k ...... nation in adult cardiomyocyte.
@en
Cyclic GMP-dependent protein k ...... nation in adult cardiomyocyte.
@nl
P2093
P2860
P356
P1476
Cyclic GMP-dependent protein k ...... nation in adult cardiomyocyte.
@en
P2093
Albert Smolenski
Rakesh C Kukreja
Suzanne M Lohmann
P2860
P304
38644-38652
P356
10.1074/JBC.M606142200
P407
P50
P577
2006-10-12T00:00:00Z