Imatinib inhibits the activation and proliferation of normal T lymphocytes in vitro.
about
Effects of nilotinib on regulatory T cells: the dose mattersThe c-Abl tyrosine kinase regulates actin remodeling at the immune synapsePR1-specific T cells are associated with unmaintained cytogenetic remission of chronic myelogenous leukemia after interferon withdrawal.Libraries of 2β-(N-substituted piperazino)-5α-androstane-3α, 17β-diols: chemical synthesis and cytotoxic effects on human leukemia HL-60 cells and on normal lymphocytes.The kinase inhibitor imatinib mesylate inhibits TNF-{alpha} production in vitro and prevents TNF-dependent acute hepatic inflammationThe transcription factor MITF is a critical regulator of GPNMB expression in dendritic cells.Imatinib mesylate enhances the malignant behavior of human breast carcinoma cells.Tolerance and efficacy of autologous or donor-derived T cells expressing CD19 chimeric antigen receptors in adult B-ALL with extramedullary leukemia.Limited Impact of Imatinib in a Murine Model of Sclerodermatous Chronic Graft-versus-Host DiseaseDasatinib, a small-molecule protein tyrosine kinase inhibitor, inhibits T-cell activation and proliferation.Hepatitis B reactivation in chronic myeloid leukemia patients receiving tyrosine kinase inhibitor.Imatinib mesylate (Gleevec) in advanced breast cancer-expressing C-Kit or PDGFR-beta: clinical activity and biological correlationsSEA antagonizes the imatinib-meditated inhibitory effects on T cell activation via the TCR signaling pathwayImmunological effects of nilotinib prophylaxis after allogeneic stem cell transplantation in patients with advanced chronic myeloid leukemia or philadelphia chromosome-positive acute lymphoblastic leukemiaSmall-molecule protein kinase inhibitors and their effects on the immune system: implications for cancer treatment.Receptor Tyrosine Kinase and Tyrosine Kinase Inhibitors: New Hope for Success in Multiple Sclerosis TherapyPlatelet-derived growth factor, transforming growth factor-beta, and connective tissue growth factor in a porcine bronchial model of obliterative bronchiolitis.Reactivation of hepatitis B virus during targeted therapies for cancer and immune-mediated disorders.Tyrosine kinase inhibitors: potential use and safety considerations in HIV-1 infection.Hepatitis B reactivation in patients receiving targeted therapies.Reactivation of resolved infection with the hepatitis B virus immune escape mutant G145R during dasatinib treatment for chronic myeloid leukemia.Risk and impact of tuberculosis in patients with chronic myeloid leukemia: a nationwide population-based study in Taiwan.Nilotinib hampers the proliferation and function of CD8+ T lymphocytes through inhibition of T cell receptor signallingNilotinib attenuates renal injury and prolongs survival in chronic kidney disease.Imatinib mesylate inhibits STAT5 phosphorylation in response to IL-7 and promotes T cell lymphopenia in chronic myelogenous leukemia patients.Low incidence rate of opportunistic and viral infections during imatinib treatment in chronic myeloid leukemia patients in early and late chronic phase.Lck is a key target of imatinib and dasatinib in T-cell activation.Does post-transplant treatment with imatinib mesylate inhibit graft-versus-leukemia?Fatal hepatitis B virus reactivation in a chronic myeloid leukemia patient during imatinib mesylate treatment.Dasatinib may not suppress the GVL effect of donor lymphocyte infusions for CML.Imatinib mesylate suppresses cytokine synthesis by activated CD4 T cells of patients with chronic myelogenous leukemia.Imatinib synergizes with donor lymphocyte infusions to achieve rapid molecular remission of CML relapsing after allogeneic stem cell transplantation.Imatinib does not impair specific antitumor T-cell immunity in patients with chronic myeloid leukemia.Maintained immunogenicity of chronic myeloid leukemia-derived dendritic cells in the presence of imatinib mesylate: implication for vaccination regimens.Incidence of second primary malignancies and related mortality in patients with imatinib-treated chronic myeloid leukemia.Targeted Therapies: Immunologic Effects and Potential Applications Outside of Cancer.Tyrosine kinase inhibitors impair B-cell immune responses in CML through off-target inhibition of kinases important for cell signaling.Assessment of bone marrow lymphocytic status during tyrosine kinase inhibitor therapy and its relation to therapy response in chronic myeloid leukaemia.Comparative suppressive effects of tyrosine kinase inhibitors imatinib and nilotinib in models of autoimmune arthritis.Therapeutics in renal disease: the road ahead for antiproliferative targets.
P2860
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P2860
Imatinib inhibits the activation and proliferation of normal T lymphocytes in vitro.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年学术文章
@wuu
2004年学术文章
@zh-cn
2004年学术文章
@zh-hans
2004年学术文章
@zh-my
2004年学术文章
@zh-sg
2004年學術文章
@yue
2004年學術文章
@zh
2004年學術文章
@zh-hant
name
Imatinib inhibits the activation and proliferation of normal T lymphocytes in vitro.
@en
Imatinib inhibits the activation and proliferation of normal T lymphocytes in vitro.
@nl
type
label
Imatinib inhibits the activation and proliferation of normal T lymphocytes in vitro.
@en
Imatinib inhibits the activation and proliferation of normal T lymphocytes in vitro.
@nl
prefLabel
Imatinib inhibits the activation and proliferation of normal T lymphocytes in vitro.
@en
Imatinib inhibits the activation and proliferation of normal T lymphocytes in vitro.
@nl
P2093
P2860
P356
P1433
P1476
Imatinib inhibits the activation and proliferation of normal T lymphocytes in vitro.
@en
P2093
Cwynarski K
Lombardi G
Macchiarulo E
P2860
P2888
P304
P356
10.1038/SJ.LEU.2403401
P577
2004-08-01T00:00:00Z
P5875
P6179
1021101569