Anionic lipids activate group IVA cytosolic phospholipase A2 via distinct and separate mechanisms.
about
Phospholipase A2 enzymes: physical structure, biological function, disease implication, chemical inhibition, and therapeutic interventionPhospholipase A2 biochemistryCeramide 1-phosphate is required for the translocation of group IVA cytosolic phospholipase A2 and prostaglandin synthesis.Ceramide kinase is required for a normal eicosanoid response and the subsequent orderly migration of fibroblastsModulation of the activity of cytosolic phospholipase A2alpha (cPLA2alpha) by cellular sphingolipids and inhibition of cPLA2alpha by sphingomyelinMammalian sphingosine kinase (SphK) isoenzymes and isoform expression: challenges for SphK as an oncotarget.A ceramide analog inhibits cPLA(2) activity and consequent PGE(2) formation in LPS-stimulated macrophages.Protease-activated receptor signaling in platelets activates cytosolic phospholipase A2α differently for cyclooxygenase-1 and 12-lipoxygenase catalysis.Ceramide kinase regulates the production of tumor necrosis factor α (TNFα) via inhibition of TNFα-converting enzyme.The molecular basis of ceramide-1-phosphate recognition by C2 domains.Characterization of eicosanoid synthesis in a genetic ablation model of ceramide kinaseCeramide 1-phosphate mediates endothelial cell invasion via the annexin a2-p11 heterotetrameric protein complex.Phospholipases A2 and inflammatory responses in the central nervous system.The role of ceramide-1-phosphate in biological functions.Sphingolipid metabolic pathway: an overview of major roles played in human diseases.Lactosylceramide-Induced Phosphorylation Signaling to Group IVA Phospholipase A2 via Reactive Oxygen Species in Tumor Necrosis Factor-α-Treated Cells.Plant phosphatidylinositol-specific phospholipase C at the center of plant innate immunity.Investigation of the biophysical properties of a fluorescently modified ceramide-1-phosphate.Ovalbumin-induced plasma interleukin-4 levels are reduced in ceramide kinase-deficient DO11.10 RAG1-/- mice.The cationic cluster of group IVA phospholipase A2 (Lys488/Lys541/Lys543/Lys544) is involved in translocation of the enzyme to phagosomes in human macrophages.Lactosylceramide interacts with and activates cytosolic phospholipase A2α.A phospholipid substrate molecule residing in the membrane surface mediates opening of the lid region in group IVA cytosolic phospholipase A2.
P2860
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P2860
Anionic lipids activate group IVA cytosolic phospholipase A2 via distinct and separate mechanisms.
description
2007 nî lūn-bûn
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2007年の論文
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2007年学术文章
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2007年学术文章
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2007年学术文章
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2007年学术文章
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2007年學術文章
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name
Anionic lipids activate group ...... tinct and separate mechanisms.
@en
Anionic lipids activate group ...... tinct and separate mechanisms.
@nl
type
label
Anionic lipids activate group ...... tinct and separate mechanisms.
@en
Anionic lipids activate group ...... tinct and separate mechanisms.
@nl
prefLabel
Anionic lipids activate group ...... tinct and separate mechanisms.
@en
Anionic lipids activate group ...... tinct and separate mechanisms.
@nl
P2093
P2860
P1476
Anionic lipids activate group ...... stinct and separate mechanisms
@en
P2093
Charles E Chalfant
Mohsin Vora
Preeti Subramanian
P2860
P304
P356
10.1194/JLR.M700356-JLR200
P577
2007-09-21T00:00:00Z