Evaluation of the ability of a battery of three in vitro genotoxicity tests to discriminate rodent carcinogens and non-carcinogens III. Appropriate follow-up testing in vivo.
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Phenobarbital induces alterations in the proteome of hepatocytes and mesenchymal cells of rat liversIdentification of BC005512 as a DNA damage responsive murine endogenous retrovirus of GLN family involved in cell growth regulationIn vitro cell transformation assays for an integrated, alternative assessment of carcinogenicity: a data-based analysis.Evaluation of the toxicity forecasting capability of EPA's ToxCast Phase I data: can ToxCast in vitro assays predict carcinogenicity?Genotoxicity of synthetic amorphous silica nanoparticles in rats following short-term exposure. Part 2: intratracheal instillation and intravenous injection.Can carcinogenic potency be predicted from in vivo genotoxicity data?: a meta-analysis of historical data.Effect of training data size and noise level on support vector machines virtual screening of genotoxic compounds from large compound libraries.Alternative strategies for carcinogenicity assessment: an efficient and simplified approach based on in vitro mutagenicity and cell transformation assays.Alternative (non-animal) methods for cosmetics testing: current status and future prospects-2010.Recent advances in in vivo genotoxicity testing: prediction of carcinogenic potential using comet and micronucleus assay in animal models.Review of genotoxicity studies of glyphosate and glyphosate-based formulations.Single cell gel electrophoresis (SCGE) and Pig-a mutation assay in vivo-tools for genotoxicity testing from a regulatory perspective: a study of benzo[a]pyrene in Ogg1(-/-) mice.Genetic toxicology in the 21st century: reflections and future directions.Dose-response assessment of four genotoxic chemicals in a combined mouse and rat micronucleus (MN) and Comet assay protocol.Development of a Medium-term Animal Model Using gpt Delta Rats to Evaluate Chemical Carcinogenicity and Genotoxicity.Alternatives to the carcinogenicity bioassay: in silico methods, and the in vitro and in vivo mutagenicity assays.New and emerging technologies for genetic toxicity testing.Micronucleus assays in rodent tissues other than bone marrow.Genotoxicity and carcinogenicity studies of antihistamines.The new ISSMIC database on in vivo micronucleus and its role in assessing genotoxicity testing strategies.Alternatives to the carcinogenicity bioassay for toxicity prediction: are we there yet?The essential comet assay: a comprehensive guide to measuring DNA damage and repair.Using immunotoxicity information to improve cancer risk assessment for polycyclic aromatic hydrocarbon mixtures.Predicting the carcinogenicity of chemicals with alternative approaches: recent advances.Genotoxicity testing approaches for the safety assessment of substances used in food contact materials prior to their authorization in the European Union.Combinations of genotoxic tests for the evaluation of group 1 IARC carcinogens.Regulatory requirements for genotoxicity assessment of plant protection product active ingredients, impurities, and metabolites.International regulatory requirements for genotoxicity testing for pharmaceuticals used in human medicine, and their impurities and metabolites.Regulatory Acceptance of Alternative Methods in the Development and Approval of Pharmaceuticals.Using in vitro structural alerts for chromosome damage to predict in vivo activity and direct future testing.Enhancing the sensitivity of the comet assay as a genotoxicity test, by combining it with bacterial repair enzyme FPG.Origin of the TTC values for compounds that are genotoxic and/or carcinogenic and an approach for their re-evaluation.Global regulatory requirements for mutagenicity assessment in the registration of industrial chemicals.Evaluation of the genotoxic and antigenotoxic potential of Baccharis dracunculifolia extract on V79 cells by the comet assay.No adverse lung effects of 7- and 28-day inhalation exposure of rats to emissions from petrodiesel fuel containing 20% rapeseed methyl esters (B20) with and without particulate filter - the FuelHealth project.The in vivo Pig-a gene mutation assay, a potential tool for regulatory safety assessment.Protective effect of (-)-epigallocatechin-3-gallate on capsaicin-induced DNA damage and oxidative stress in human erythrocyes and leucocytes in vitro.Thinner inhalation effects on oxidative stress and DNA repair in a rat model of abuse.Assessment of the efficacy of Aspergillus sp. EL-2 in textile waste water treatment.Comparison of Comet assay dose-response for ethyl methanesulfonate using freshly prepared versus cryopreserved tissues.
P2860
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P2860
Evaluation of the ability of a battery of three in vitro genotoxicity tests to discriminate rodent carcinogens and non-carcinogens III. Appropriate follow-up testing in vivo.
description
2008 nî lūn-bûn
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2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
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2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
@zh
2008年學術文章
@zh-hant
name
Evaluation of the ability of a ...... ate follow-up testing in vivo.
@en
Evaluation of the ability of a ...... ate follow-up testing in vivo.
@nl
type
label
Evaluation of the ability of a ...... ate follow-up testing in vivo.
@en
Evaluation of the ability of a ...... ate follow-up testing in vivo.
@nl
prefLabel
Evaluation of the ability of a ...... ate follow-up testing in vivo.
@en
Evaluation of the ability of a ...... ate follow-up testing in vivo.
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P1433
P1476
Evaluation of the ability of a ...... ate follow-up testing in vivo.
@en
P2093
David Kirkland
Günter Speit
P304
P356
10.1016/J.MRGENTOX.2008.05.002
P407
P577
2008-05-16T00:00:00Z