A Drosophila model of early onset torsion dystonia suggests impairment in TGF-beta signaling.
about
Dtorsin, the Drosophila ortholog of the early-onset dystonia TOR1A (DYT1), plays a novel role in dopamine metabolismA Drosophila model of GSS syndrome suggests defects in active zones are responsible for pathogenesis of GSS syndrome.Mutant torsinA interacts with tyrosine hydroxylase in cultured cells.Altered dendritic morphology of Purkinje cells in Dyt1 ΔGAG knock-in and purkinje cell-specific Dyt1 conditional knockout mice.Untethering the nuclear envelope and cytoskeleton: biologically distinct dystonias arising from a common cellular dysfunctionDystonia, facial dysmorphism, intellectual disability and breast cancer associated with a chromosome 13q34 duplication and overexpression of TFDP1: case reportBehavioral and electrophysiological characterization of Dyt1 heterozygous knockout mice.The pathogenic human Torsin A in Drosophila activates the unfolded protein response and increases susceptibility to oxidative stress.Motor deficits and hyperactivity in Dyt1 knockdown mice.Mutations in CIZ1 cause adult onset primary cervical dystonia.The ubiquitin ligase F-box/G-domain protein 1 promotes the degradation of the disease-linked protein torsinA through the ubiquitin-proteasome pathway and macroautophagy.Invertebrate models of dystonia.Abnormal motor function and dopamine neurotransmission in DYT1 DeltaGAG transgenic mice.Drosophila Torsin Protein Regulates Motor Control and Stress Sensitivity and Forms a Complex with Fragile-X Mental Retardation ProteinGlial elements contribute to stress-induced torsinA expression in the CNS and peripheral nervous systemEngineering animal models of dystoniaA role for cerebellum in the hereditary dystonia DYT1.Emerging common molecular pathways for primary dystonia.Striatal cholinergic interneurons in isolated generalized dystonia-rationale and perspectives for stem cell-derived cellular models.Function of dopamine transporter is compromised in DYT1 transgenic animal model in vivoPharmacogenetic regulation of acetylcholinesterase activity in Drosophila reveals the regulatory mechanisms of AChE inhibitors in synaptic plasticity.The precise subcellular localization of Dlg in the Drosophila larva body wall using improved pre-embedding immuno-EM.Impaired Wnt signaling in dopamine containing neurons is associated with pathogenesis in a rotenone triggered Drosophila Parkinson's disease model.Regulation of synaptic architecture and synaptic vesicle pools by Nervous wreck at Drosophila Type 1b glutamatergic synapses.
P2860
Q27316703-533BF955-97A1-49B7-A2E0-8F77BB30AE83Q30509496-F014E1CD-0C76-4A68-837B-F876F9FA47B1Q33750936-DF3206AB-4B1A-40BF-844C-07666D104691Q33867544-01F2F3B5-58ED-4924-8422-31F7D9E2144DQ34638417-2F0CDC2C-261B-4498-AA5B-54078423AA2DQ34815903-EBF3C2AC-188E-47A6-BB9C-ED3E56FFFB11Q35208664-7AF9C2E4-2F14-423D-8E76-5B92B981714BQ35555819-B450CF63-567E-4F6B-97CC-3377CFC71CF6Q35629540-03C895C9-5623-4D61-AB6F-BFDB05B64301Q35907284-76C62AED-630C-4067-8E16-6CE59F4E20FFQ36331007-B643197F-24AD-4433-ABCA-689C9F8F8BB4Q36634138-EB05466B-1E40-49EA-9352-E6E5666B35AEQ36666604-F41C9169-6EDE-4C0C-A455-618A4E93262DQ36996330-1B212124-5E5F-475A-9CEE-1B19C4672C3DQ37001321-28B83920-ADA5-4C5D-9BDA-F95257A65CF4Q37239952-9C52A5CD-12DB-4F5C-BAC3-B698A8825719Q37684995-45524A42-11D6-4230-B2A7-BD17E24366DAQ38124786-3A37AEC9-A43A-40CB-AE77-32E129B577C6Q38239643-08A3424E-79FF-4754-8CE4-E38A98A83E87Q42593925-5D1BD0F7-3670-4919-B0A3-C83A82780731Q46640567-ED36FDDA-A510-4A0E-AC8A-7A2E298E09FDQ48134366-0B195FC3-B2CD-4699-AD4A-6EE0C98F5DD3Q49417153-642991BE-7B15-4574-868B-CA553EEC9E37Q55056714-82362043-C2BA-466E-A110-5064858442E6
P2860
A Drosophila model of early onset torsion dystonia suggests impairment in TGF-beta signaling.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年学术文章
@wuu
2004年学术文章
@zh-cn
2004年学术文章
@zh-hans
2004年学术文章
@zh-my
2004年学术文章
@zh-sg
2004年學術文章
@yue
2004年學術文章
@zh
2004年學術文章
@zh-hant
name
A Drosophila model of early on ...... airment in TGF-beta signaling.
@en
A Drosophila model of early on ...... airment in TGF-beta signaling.
@nl
type
label
A Drosophila model of early on ...... airment in TGF-beta signaling.
@en
A Drosophila model of early on ...... airment in TGF-beta signaling.
@nl
prefLabel
A Drosophila model of early on ...... airment in TGF-beta signaling.
@en
A Drosophila model of early on ...... airment in TGF-beta signaling.
@nl
P2093
P2860
P356
P1476
A Drosophila model of early on ...... airment in TGF-beta signaling.
@en
P2093
Barry Ganetzky
Kimberly Rehfeld
Young-Ho Koh
P2860
P304
P356
10.1093/HMG/DDH208
P577
2004-07-21T00:00:00Z