Scanning mutagenesis of omega-atracotoxin-Hv1a reveals a spatially restricted epitope that confers selective activity against insect calcium channels.
about
From foe to friend: using animal toxins to investigate ion channel functionω-Tbo-IT1-New Inhibitor of Insect Calcium Channels Isolated from Spider Venom.Solution structure of agelenin, an insecticidal peptide isolated from the spider Agelena opulenta, and its structural similarities to insect-specific calcium channel inhibitorsThe insecticidal neurotoxin Aps III is an atypical knottin peptide that potently blocks insect voltage-gated sodium channelsA Tarantula-Venom Peptide Antagonizes the TRPA1 Nociceptor Ion Channel by Binding to the S1–S4 Gating DomainThe insecticidal spider toxin SFI1 is a knottin peptide that blocks the pore of insect voltage-gated sodium channels via a large β-hairpin loopRecombinant expression of margatoxin and agitoxin-2 in Pichia pastoris: an efficient method for production of KV1.3 channel blockersFusion to snowdrop lectin magnifies the oral activity of insecticidal ω-Hexatoxin-Hv1a peptide by enabling its delivery to the central nervous systemMolecular basis of the remarkable species selectivity of an insecticidal sodium channel toxin from the African spider Augacephalus ezendamiDiversification of a single ancestral gene into a successful toxin superfamily in highly venomous Australian funnel-web spiders.Functional expression of spider neurotoxic peptide huwentoxin-I in E. coli.Arthropod venoms: a vast arsenal of insecticidal neuropeptides.Spider-venom peptides as bioinsecticidesSpider-venom peptides as therapeutics.Heterologous expression and purification of neurotoxic Hainantoxin-III in E. coli.The Cystine Knot Is Responsible for the Exceptional Stability of the Insecticidal Spider Toxin ω-Hexatoxin-Hv1aThe insecticidal potential of venom peptides.Spider venomics: implications for drug discovery.Optimising expression of the recombinant fusion protein biopesticide ω-hexatoxin-Hv1a/GNA in Pichia pastoris: sequence modifications and a simple method for the generation of multi-copy strains.The Janus-faced atracotoxins are specific blockers of invertebrate K(Ca) channels.Scanning mutagenesis reveals a role for serine 189 of the heterotrimeric G-protein beta 1 subunit in the inhibition of N-type calcium channels.Toxin delivery by the coat protein of an aphid-vectored plant virus provides plant resistance to aphids.Effect of insecticidal fusion proteins containing spider toxins targeting sodium and calcium ion channels on pyrethroid-resistant strains of peach-potato aphid (Myzus persicae).
P2860
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P2860
Scanning mutagenesis of omega-atracotoxin-Hv1a reveals a spatially restricted epitope that confers selective activity against insect calcium channels.
description
2004 nî lūn-bûn
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name
Scanning mutagenesis of omega- ...... ainst insect calcium channels.
@en
Scanning mutagenesis of omega- ...... ainst insect calcium channels.
@nl
type
label
Scanning mutagenesis of omega- ...... ainst insect calcium channels.
@en
Scanning mutagenesis of omega- ...... ainst insect calcium channels.
@nl
prefLabel
Scanning mutagenesis of omega- ...... ainst insect calcium channels.
@en
Scanning mutagenesis of omega- ...... ainst insect calcium channels.
@nl
P2093
P356
P1476
Scanning mutagenesis of omega- ...... ainst insect calcium channels.
@en
P2093
André Ménez
Clinton J Doering
Hugo W Tedford
Nicolas Gilles
P304
44133-44140
P356
10.1074/JBC.M404006200
P407
P577
2004-08-11T00:00:00Z