Hepsin promotes prostate cancer progression and metastasis.
about
Pro-urokinase-type plasminogen activator is a substrate for hepsinUpstream stimulatory factor 2, a novel FoxA1-interacting protein, is involved in prostate-specific gene expressionMouse Models in Prostate Cancer Translational Research: From Xenograft to PDXRebuilding cancer metastasis in the mouseAllosteric antibody inhibition of human hepsin proteaseHepsin activates pro-hepatocyte growth factor and is inhibited by hepatocyte growth factor activator inhibitor-1B (HAI-1B) and HAI-2.Identification of hepatocyte growth factor activator inhibitor-1B as a potential physiological inhibitor of prostasinUsing rule-based machine learning for candidate disease gene prioritization and sample classification of cancer gene expression dataProstate cancer progression and metastasis: potential regulatory pathways for therapeutic targeting.Robust prostate cancer marker genes emerge from direct integration of inter-study microarray data.Hepatocyte growth factor is a preferred in vitro substrate for human hepsin, a membrane-anchored serine protease implicated in prostate and ovarian cancersInhibition of human matriptase by eglin c variants.Characterization of a method for profiling gene expression in cells recovered from intact human prostate tissue using RNA linear amplification.Identification and characterization of small-molecule inhibitors of hepsinAccurate molecular classification of cancer using simple rulesLocal protease signaling contributes to neural tube closure in the mouse embryoOptimization based tumor classification from microarray gene expression data.Association of hepsin gene variants with prostate cancer risk and prognosisMouse models of prostate cancer: picking the best model for the question.Neighborhood rough set reduction-based gene selection and prioritization for gene expression profile analysis and molecular cancer classification.Proteolysis-induced N-terminal ectodomain shedding of the integral membrane glycoprotein CUB domain-containing protein 1 (CDCP1) is accompanied by tyrosine phosphorylation of its C-terminal domain and recruitment of Src and PKCdelta.Hepsin cooperates with MYC in the progression of adenocarcinoma in a prostate cancer mouse model.Partition decoupling for multi-gene analysis of gene expression profiling dataAn allosteric anti-hepsin antibody derived from a constrained phage display library.Phenotypic analysis of mice lacking the Tmprss2-encoded proteaseEpigenetics of prostate cancer: beyond DNA methylationThe host microenvironment influences prostate cancer invasion, systemic spread, bone colonization, and osteoblastic metastasis.Wnt/β-catenin activation promotes prostate tumor progression in a mouse modelRegulation of hepatocyte activator inhibitor-1 expression by androgen and oncogenic transformation in the prostate.Matrix-dependent regulation of AKT in Hepsin-overexpressing PC3 prostate cancer cells.The androgen-regulated protease TMPRSS2 activates a proteolytic cascade involving components of the tumor microenvironment and promotes prostate cancer metastasis.The functional role of reactive stroma in benign prostatic hyperplasia.Identification of hepsin and protein disulfide isomerase A3 as targets of gelatinolytic action in rat ovarian granulosa cells during the periovulatory periodThe role of the cell-cell interactions in cancer progression.Migrating with myosin VI.A novel role of myosin VI in human prostate cancerLow expression levels of hepsin and TMPRSS3 are associated with poor breast cancer survivalTumor suppressor function of Liver kinase B1 (Lkb1) is linked to regulation of epithelial integrityIn vitro and in vivo model systems used in prostate cancer research.Epigenetic Silencing of SPINT2 Promotes Cancer Cell Motility via HGF-MET Pathway Activation in Melanoma
P2860
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P2860
Hepsin promotes prostate cancer progression and metastasis.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年学术文章
@wuu
2004年学术文章
@zh-cn
2004年学术文章
@zh-hans
2004年学术文章
@zh-my
2004年学术文章
@zh-sg
2004年學術文章
@yue
2004年學術文章
@zh
2004年學術文章
@zh-hant
name
Hepsin promotes prostate cancer progression and metastasis.
@en
Hepsin promotes prostate cancer progression and metastasis.
@nl
type
label
Hepsin promotes prostate cancer progression and metastasis.
@en
Hepsin promotes prostate cancer progression and metastasis.
@nl
prefLabel
Hepsin promotes prostate cancer progression and metastasis.
@en
Hepsin promotes prostate cancer progression and metastasis.
@nl
P2093
P1433
P1476
Hepsin promotes prostate cancer progression and metastasis.
@en
P2093
Janni Mirosevich
John Chevillet
Olga Klezovitch
Richard L Roberts
Robert J Matusik
Valeri Vasioukhin
P304
P356
10.1016/J.CCR.2004.07.008
P577
2004-08-01T00:00:00Z