The Co-chaperone Sba1 connects the ATPase reaction of Hsp90 to the progression of the chaperone cycle.
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Hsp90 cochaperones p23 and FKBP4 physically interact with hAgo2 and activate RNA interference-mediated silencing in mammalian cellsReview: The HSP90 molecular chaperone-an enigmatic ATPaseSteroid Receptor-Associated Immunophilins: A Gateway to Steroid SignallingSgt1p is a unique co-chaperone that acts as a client adaptor to link Hsp90 to Skp1p.Hsp90 is regulated by a switch point in the C-terminal domainMixed Hsp90-cochaperone complexes are important for the progression of the reaction cycle.Intra- and intermonomer interactions are required to synergistically facilitate ATP hydrolysis in Hsp90.The co-chaperone Hch1 regulates Hsp90 function differently than its homologue Aha1 and confers sensitivity to yeast to the Hsp90 inhibitor NVP-AUY922Crystal structure of an Hsp90-nucleotide-p23/Sba1 closed chaperone complexDifferential modulation of functional dynamics and allosteric interactions in the Hsp90-cochaperone complexes with p23 and Aha1: a computational study.Detection of changes in gene regulatory patterns, elicited by perturbations of the Hsp90 molecular chaperone complex, by visualizing multiple experiments with an animation.Hsp90 nuclear accumulation in quiescence is linked to chaperone function and spore development in yeast.The Hsp90 cochaperone, FKBP51, increases Tau stability and polymerizes microtubules.Defective glucocorticoid receptor signaling and keratinocyte-autonomous defects contribute to skin phenotype of mouse embryos lacking the Hsp90 co-chaperone p23.The balanced regulation of Hsc70 by DNJ-13 and UNC-23 is required for muscle functionality.Probing molecular mechanisms of the Hsp90 chaperone: biophysical modeling identifies key regulators of functional dynamics.The Hsp90 co-chaperone p23 of Toxoplasma gondii: Identification, functional analysis and dynamic interactome determination.Characterization of plant p23-like proteins for their co-chaperone activitiesN-terminal domain of human Hsp90 triggers binding to the cochaperone p23.Enforced N-domain proximity stimulates Hsp90 ATPase activity and is compatible with function in vivo.The charged linker of the molecular chaperone Hsp90 modulates domain contacts and biological function.Co-chaperone p23 regulates C. elegans Lifespan in Response to Temperature.Nucleotide-dependent interaction of Saccharomyces cerevisiae Hsp90 with the cochaperone proteins Sti1, Cpr6, and Sba1.Leishmania donovani P23 protects parasites against HSP90 inhibitor-mediated growth arrest.Hsp90-Associated Immunophilin Homolog Cpr7 Is Required for the Mitotic Stability of [URE3] Prion in Saccharomyces cerevisiae.p23/Sba1p protects against Hsp90 inhibitors independently of its intrinsic chaperone activityA Remodeled Hsp90 Molecular Chaperone Ensemble with the Novel Cochaperone Aarsd1 Is Required for Muscle Differentiation.Conformational dynamics of the molecular chaperone Hsp90Contributions of co-chaperones and post-translational modifications towards Hsp90 drug sensitivity.Molecular cochaperones: tumor growth and cancer treatment.ATP binding to Hsp90 is sufficient for effective chaperoning of p53 protein.Differences in conformational dynamics within the Hsp90 chaperone family reveal mechanistic insightsThe Mechanism of Hsp90 ATPase Stimulation by Aha1Cdc37-Hsp90 complexes are responsive to nucleotide-induced conformational changes and binding of further cofactors.Dynamics of the regulation of Hsp90 by the co-chaperone Sti1.Characterization of the Grp94/OS-9 chaperone-lectin complex.The charged linker region is an important regulator of Hsp90 function.Preventing illicit liaisons in Poland.Localization of sites of interaction between p23 and Hsp90 in solution.Conserved conformational changes in the ATPase cycle of human Hsp90.
P2860
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P2860
The Co-chaperone Sba1 connects the ATPase reaction of Hsp90 to the progression of the chaperone cycle.
description
2004 nî lūn-bûn
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2004年の論文
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2004年学术文章
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2004年学术文章
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2004年学术文章
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2004年学术文章
@zh-hans
2004年学术文章
@zh-my
2004年学术文章
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2004年學術文章
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2004年學術文章
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name
The Co-chaperone Sba1 connects ...... ession of the chaperone cycle.
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The Co-chaperone Sba1 connects ...... ession of the chaperone cycle.
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The Co-chaperone Sba1 connects ...... ession of the chaperone cycle.
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The Co-chaperone Sba1 connects ...... ession of the chaperone cycle.
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The Co-chaperone Sba1 connects ...... ession of the chaperone cycle.
@en
The Co-chaperone Sba1 connects ...... ession of the chaperone cycle.
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P1476
The Co-chaperone Sba1 connects ...... ession of the chaperone cycle.
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P2093
Johannes Buchner
Stefan Walter
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P356
10.1016/J.JMB.2004.07.064
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P577
2004-10-01T00:00:00Z