The N6-methyladenosine (m6A)-forming enzyme METTL3 controls myeloid differentiation of normal hematopoietic and leukemia cells.
about
METTL14 Inhibits Hematopoietic Stem/Progenitor Differentiation and Promotes Leukemogenesis via mRNA m6A Modification.Dynamic m6A modification regulates local translation of mRNA in axons.Reading m6A in the Transcriptome: m6A-Binding Proteins.An epitranscriptomic vulnerability in myeloid malignancies.Addition of m6A to SV40 late mRNAs enhances viral structural gene expression and replication.Impact of DNA and RNA Methylation on Radiobiology and Cancer Progression.RNA N6-methyladenosine modification in cancers: current status and perspectives.Zc3h13/Flacc is required for adenosine methylation by bridging the mRNA-binding factor Rbm15/Spenito to the m6A machinery component Wtap/Fl(2)d.The SMAD2/3 interactome reveals that TGFβ controls m6A mRNA methylation in pluripotency.Multiple functions of m6A RNA methylation in cancer.Epitranscriptomics of cancer.c-MYC and reactive oxygen species play roles in tetrandrine-induced leukemia differentiation.Uncovering the Role of RNA-Binding Proteins in Gene Expression in the Immune System.Dynamic transcriptomic m6A decoration: writers, erasers, readers and functions in RNA metabolism.Ythdf2-mediated m6A mRNA clearance modulates neural development in mice.Enhancing Epitranscriptome Module Detection from m6A-Seq Data Using Threshold-Based Measurement Weighting Strategy.The dual role of N6-methyladenosine modification of RNAs is involved in human cancersSuppression of mA reader Ythdf2 promotes hematopoietic stem cell expansionEmerging function of N6-methyladenosine in cancerTranslation acrobatics: how cancer cells exploit alternate modes of translational initiationN6-Methyladenosine in RNA and DNA: An Epitranscriptomic and Epigenetic Player Implicated in Determination of Stem Cell FateAberrant Regulation of mRNA m⁶A Modification in Cancer DevelopmentRefined RIP-seq protocol for epitranscriptome analysis with low input materialsN6-methyladenine RNA modification and cancersN6-Methyladenosine Role in Acute Myeloid LeukaemiamRNA circularization by METTL3-eIF3h enhances translation and promotes oncogenesisMettl3-mediated mA RNA methylation regulates the fate of bone marrow mesenchymal stem cells and osteoporosis
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P2860
The N6-methyladenosine (m6A)-forming enzyme METTL3 controls myeloid differentiation of normal hematopoietic and leukemia cells.
description
2017 nî lūn-bûn
@nan
2017年の論文
@ja
2017年学术文章
@wuu
2017年学术文章
@zh
2017年学术文章
@zh-cn
2017年学术文章
@zh-hans
2017年学术文章
@zh-my
2017年学术文章
@zh-sg
2017年學術文章
@yue
2017年學術文章
@zh-hant
name
The N6-methyladenosine (m6A)-f ...... atopoietic and leukemia cells.
@en
The N6-methyladenosine
@nl
type
label
The N6-methyladenosine (m6A)-f ...... atopoietic and leukemia cells.
@en
The N6-methyladenosine
@nl
prefLabel
The N6-methyladenosine (m6A)-f ...... atopoietic and leukemia cells.
@en
The N6-methyladenosine
@nl
P2093
P2860
P50
P356
P1433
P1476
The N6-methyladenosine (m6A)-f ...... matopoietic and leukemia cells
@en
P2093
Ari Melnick
Arthur Chow
Brian F Pickering
Christopher E Mason
Christopher Famulare
Diu Nguyen
Francine E Garrett-Bakelman
Gerard Minuesa
Jessica Schulman
Martin Carroll
P2860
P2888
P304
P356
10.1038/NM.4416
P407
P577
2017-09-18T00:00:00Z
P6179
1091829691