Regional heterogeneity for the intracranial self-administration of ethanol and acetaldehyde within the ventral tegmental area of alcohol-preferring (P) rats: involvement of dopamine and serotonin. - Wikidata - awgldk - TriplyDB

Regional heterogeneity for the intracranial self-administration of ethanol and acetaldehyde within the ventral tegmental area of alcohol-preferring (P) rats: involvement of dopamine and serotonin.

Regional heterogeneity for the intracranial self-administration of ethanol and acetaldehyde within the ventral tegmental area of alcohol-preferring (P) rats: involvement of dopamine and serotonin.

http://www.wikidata.org/entity/Q45071442

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Ethanol as a prodrug: brain metabolism of ethanol mediates its reinforcing effects Brain reward circuitry beyond the mesolimbic dopamine system: a neurobiological theory Dopamine reward circuitry: two projection systems from the ventral midbrain to the nucleus accumbens-olfactory tubercle complex.What is in that drink: the biological actions of ethanol, acetaldehyde, and salsolinol Neurocircuitry of drug reward Ethanol action on dopaminergic neurons in the ventral tegmental area: interaction with intrinsic ion channels and neurotransmitter inputs.Involvement of dopamine D2 receptors in addictive-like behaviour for acetaldehyde Alcohol-preferring P rats emit spontaneous 22-28 kHz ultrasonic vocalizations that are altered by acute and chronic alcohol experience.Mystic Acetaldehyde: The Never-Ending Story on Alcoholism Involvement of local serotonin-2A but not serotonin-1B receptors in the reinforcing effects of ethanol within the posterior ventral tegmental area of female Wistar rats.Ethanol is self-administered into the nucleus accumbens shell, but not the core: evidence of genetic sensitivity Differential effects of dopamine D2 and GABA(A) receptor antagonists on dopamine neurons between the anterior and posterior ventral tegmental area of female Wistar rats Sensitization of ventral tegmental area dopamine neurons to the stimulating effects of ethanol The role of 5-HT3 receptors in drug abuse and as a target for pharmacotherapy.Limited access to ethanol increases the number of spontaneously active dopamine neurons in the posterior ventral tegmental area of nondependent P rats.Reinforcing properties and neurochemical response of ethanol within the posterior ventral tegmental area are enhanced in adulthood by periadolescent ethanol consumption Primary reinforcing effects of nicotine are triggered from multiple regions both inside and outside the ventral tegmental area.Pharmacological recruitment of the GABAergic tail of the ventral tegmental area by acute drug exposure.Microinjections of acetaldehyde or salsolinol into the posterior ventral tegmental area increase dopamine release in the nucleus accumbens shell.The posterior ventral tegmental area mediates alcohol-seeking behavior in alcohol-preferring rats Nicotine-mediated activation of dopaminergic neurons in distinct regions of the ventral tegmental area.Ethanol drinking reduces extracellular dopamine levels in the posterior ventral tegmental area of nondependent alcohol-preferring rats.An acetaldehyde-sequestering agent inhibits appetitive reinforcement and behavioral stimulation induced by ethanol in preweanling rats.GABAergic actions mediate opposite ethanol effects on dopaminergic neurons in the anterior and posterior ventral tegmental area.Activation of serotonin-3 receptors increases dopamine release within the ventral tegmental area of Wistar and alcohol-preferring (P) rats Serotonin-3 receptors in the posterior ventral tegmental area regulate ethanol self-administration of alcohol-preferring (P) rats.Prolonged increase in the sensitivity of the posterior ventral tegmental area to the reinforcing effects of ethanol following repeated exposure to cycles of ethanol access and deprivation.Behavioral and neurotransmitter specific roles for the ventral tegmental area in reinforcer-seeking and intake Effects of naltrexone and LY255582 on ethanol maintenance, seeking, and relapse responding by alcohol-preferring (P) rats.A conceptualization of integrated actions of ethanol contributing to its GABAmimetic profile: a commentary.Central reinforcing effects of ethanol are blocked by catalase inhibition The reinforcing effects of ethanol within the posterior ventral tegmental area depend on dopamine neurotransmission to forebrain cortico-limbic systems Genetic and Environmental Predictors of Alcohol Use in Asian American Young Adults The alcohol-preferring P rat and animal models of excessive alcohol drinking.Glycyl-glutamine reduces ethanol intake at three reward sites in P rats.Locus coeruleus neuronal activity determines proclivity to consume alcohol in a selectively-bred line of rats that readily consumes alcohol.Acetaldehyde involvement in ethanol's postabsortive effects during early ontogeny.Co-administration of ethanol and nicotine: the enduring alterations in the rewarding properties of nicotine and glutamate activity within the mesocorticolimbic system of female alcohol-preferring (P) rats Selective breeding for high alcohol preference increases the sensitivity of the posterior VTA to the reinforcing effects of nicotine.Elucidating the biological basis for the reinforcing actions of alcohol in the mesolimbic dopamine system: the role of active metabolites of alcohol

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P2860

Regional heterogeneity for the intracranial self-administration of ethanol and acetaldehyde within the ventral tegmental area of alcohol-preferring (P) rats: involvement of dopamine and serotonin.

http://www.wikidata.org/entity/Q45071442

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Regional heterogeneity for the ...... ent of dopamine and serotonin.

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Alejandro Zaffaroni

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Avram Goldstein

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James M Murphy

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Richard L Bell

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Ting-Kai Li

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William J McBride

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Ying Zhang

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Zachary A Rodd

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P2860

Catalase and the production of brain acetaldehyde: a possible mediator of the psychopharmacological effects of ethanol.

Intraventricular self-administration of acetaldehyde, but not ethanol, in naive laboratory rats.

Neurocircuitry targets in ethanol reward and dependence.

Role of acetaldehyde in the actions of ethanol on the brain--a review.

The 5-HT3 receptor antagonists LY 277359 and granisetron potentiate the suppressant action of apomorphine on the basal firing rate of ventral tegmental dopamine cells.

The acetaldehyde content in rat brain during ethanol metabolism.

D2 receptors inhibit the secretory process downstream from calcium influx in dopaminergic neurons: implication of K+ channels.

The reinforcing effects of acetaldehyde in the posterior ventral tegmental area of alcohol-preferring rats.

Brain catalase inhibition blocks ethanol-related decrease of blood luteinizing hormone levels in mice.

Cocaine is self-administered into the shell but not the core of the nucleus accumbens of Wistar rats.

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10.1038/SJ.NPP.1300561

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2

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30

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1043345004

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