N-retinylidene-phosphatidylethanolamine is the preferred retinoid substrate for the photoreceptor-specific ABC transporter ABCA4 (ABCR).
about
Dominant negative mechanism underlies autosomal dominant Stargardt-like macular dystrophy linked to mutations in ELOVL4Differential phospholipid substrates and directional transport by ATP-binding cassette proteins ABCA1, ABCA7, and ABCA4 and disease-causing mutantsCorrection of the disease phenotype in the mouse model of Stargardt disease by lentiviral gene therapyMammalian P4-ATPases and ABC transporters and their role in phospholipid transportIntracellular transport of fat-soluble vitamins A and ESingle-neuron and genetic correlates of autistic behavior in macaque.The lipid translocase, ABCA4: seeing is believing.Chemistry of the retinoid (visual) cycleRole of the C terminus of the photoreceptor ABCA4 transporter in protein folding, function, and retinal degenerative diseases.ABCA4-associated retinal degenerations spare structure and function of the human parapapillary retina.Genetic and epigenetic factors at COL2A1 and ABCA4 influence clinical outcome in congenital toxoplasmosisPhospholipid meets all-trans-retinal: the making of RPE bisretinoidsDifferential distribution of proteins and lipids in detergent-resistant and detergent-soluble domains in rod outer segment plasma membranes and disks.Accelerated accumulation of lipofuscin pigments in the RPE of a mouse model for ABCA4-mediated retinal dystrophies following Vitamin A supplementationRetinal very long-chain PUFAs: new insights from studies on ELOVL4 proteinInteraction of extracellular domain 2 of the human retina-specific ATP-binding cassette transporter (ABCA4) with all-trans-retinalEffects of potent inhibitors of the retinoid cycle on visual function and photoreceptor protection from light damage in mice.The retinal pigment epithelium in health and diseaseThe ATP-binding cassette transporter ABCA4: structural and functional properties and role in retinal disease.Deducing the pathogenic contribution of recessive ABCA4 alleles in an outbred populationDefective lipid transport and biosynthesis in recessive and dominant Stargardt macular degenerationVitamin A metabolism: an update.Rod outer segment retinol formation is independent of Abca4, arrestin, rhodopsin kinase, and rhodopsin palmitylationRole of membrane integrity on G protein-coupled receptors: Rhodopsin stability and function.Posttranslational modifications of the photoreceptor-specific ABC transporter ABCA4Membrane receptors and transporters involved in the function and transport of vitamin A and its derivatives.The bisretinoids of retinal pigment epitheliumA-Subclass ATP-Binding Cassette Proteins in Brain Lipid Homeostasis and Neurodegeneration.Lipofuscin and N-retinylidene-N-retinylethanolamine (A2E) accumulate in retinal pigment epithelium in absence of light exposure: their origin is 11-cis-retinal.Light and inherited retinal degeneration.Diseases of intramembranous lipid transport.Serotype-dependent packaging of large genes in adeno-associated viral vectors results in effective gene delivery in mice.Diseases caused by defects in the visual cycle: retinoids as potential therapeutic agentsMolecular organization and ATP-induced conformational changes of ABCA4, the photoreceptor-specific ABC transporterTransduction of photoreceptors with equine infectious anemia virus lentiviral vectors: safety and biodistribution of StarGen for Stargardt diseaseOxidative stress, innate immunity, and age-related macular degenerationInterphotoreceptor retinoid-binding protein is the physiologically relevant carrier that removes retinol from rod photoreceptor outer segments.Stargardt's disease and the ABCR gene.Macular pigment and lutein supplementation in ABCA4-associated retinal degenerationsNovel ABCA4 compound heterozygous mutations cause severe progressive autosomal recessive cone-rod dystrophy presenting as Stargardt disease.
P2860
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P2860
N-retinylidene-phosphatidylethanolamine is the preferred retinoid substrate for the photoreceptor-specific ABC transporter ABCA4 (ABCR).
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年学术文章
@wuu
2004年学术文章
@zh
2004年学术文章
@zh-cn
2004年学术文章
@zh-hans
2004年学术文章
@zh-my
2004年学术文章
@zh-sg
2004年學術文章
@yue
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@zh-hant
name
N-retinylidene-phosphatidyleth ...... ABC transporter ABCA4 (ABCR).
@en
N-retinylidene-phosphatidyleth ...... specific ABC transporter ABCA4
@nl
type
label
N-retinylidene-phosphatidyleth ...... ABC transporter ABCA4 (ABCR).
@en
N-retinylidene-phosphatidyleth ...... specific ABC transporter ABCA4
@nl
prefLabel
N-retinylidene-phosphatidyleth ...... ABC transporter ABCA4 (ABCR).
@en
N-retinylidene-phosphatidyleth ...... specific ABC transporter ABCA4
@nl
P2093
P2860
P356
P1476
N-retinylidene-phosphatidyleth ...... ABC transporter ABCA4 (ABCR).
@en
P2093
Ming Zhong
Robert S Molday
Seelochan Beharry
P2860
P304
53972-53979
P356
10.1074/JBC.M405216200
P407
P577
2004-10-07T00:00:00Z