COOH-terminal 26-amino acid residues of progastrin are sufficient for stimulation of mitosis in murine colonic epithelium in vivo.

COOH-terminal 26-amino acid residues of progastrin are sufficient for stimulation of mitosis in murine colonic epithelium in vivo.

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http://www.wikidata.org/entity/Q45108345
Progastrin Peptides Increase the Risk of Developing Colonic Tumors: Impact on Colonic Stem CellsAnnexin II binds progastrin and gastrin-like peptides, and mediates growth factor effects of autocrine and exogenous gastrins on colon cancer and intestinal epithelial cells.Clathrin mediates endocytosis of progastrin and activates MAPKs: role of cell surface annexin A2.Progastrin overexpression imparts tumorigenic/metastatic potential to embryonic epithelial cells: phenotypic differences between transformed and nontransformed stem cells.Role of gastrin-peptides in Barrett's and colorectal carcinogenesis.NF-κB1, NF-κB2 and c-Rel differentially regulate susceptibility to colitis-associated adenoma development in C57BL/6 mice.P53 gene mutation increases progastrin dependent colonic proliferation and colon cancer formation in miceGastrin attenuates ischemia-reperfusion-induced intestinal injury in rats.Inactivating cholecystokinin-2 receptor inhibits progastrin-dependent colonic crypt fission, proliferation, and colorectal cancer in mice.Functional cross-talk between beta-catenin and NFkappaB signaling pathways in colonic crypts of mice in response to progastrin.The production and role of gastrin-17 and gastrin-17-gly in gastrointestinal cancers.The structure of bioactive analogs of the N-terminal region of gastrin-17.Bioactivity of analogs of the N-terminal region of gastrin-17.Flow cytometric detection of progastrin interaction with gastrointestinal cells.The G-protein coupled receptor 56, expressed in colonic stem and cancer cells, binds progastrin to promote proliferation and carcinogenesis.Activation of NF-kappaB is required for mediating proliferative and antiapoptotic effects of progastrin on proximal colonic crypts of mice, in vivo.Annexin A2 mediates up-regulation of NF-κB, β-catenin, and stem cell in response to progastrin in mice and HEK-293 cells.
P2860

COOH-terminal 26-amino acid residues of progastrin are sufficient for stimulation of mitosis in murine colonic epithelium in vivo.

Item
http://www.wikidata.org/entity/Q45108345
description
2004 nî lūn-bûn
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name
COOH-terminal 26-amino acid re ...... ne colonic epithelium in vivo.
@en
COOH-terminal 26-amino acid re ...... ne colonic epithelium in vivo.
@nl
type
label
COOH-terminal 26-amino acid re ...... ne colonic epithelium in vivo.
@en
COOH-terminal 26-amino acid re ...... ne colonic epithelium in vivo.
@nl
prefLabel
COOH-terminal 26-amino acid re ...... ne colonic epithelium in vivo.
@en
COOH-terminal 26-amino acid re ...... ne colonic epithelium in vivo.
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P433
P478
P50
P577
P5875
P698
P356
P1433
P1476
COOH-terminal 26-amino acid re ...... ne colonic epithelium in vivo.
@en
P2093
P2860
P304
P31
P356
P433
P478
P50
P577
P5875
P698