Loop flexibility and solvent dynamics as determinants for the selective inhibition of cyclin-dependent kinase 4: comparative molecular dynamics simulation studies of CDK2 and CDK4.

Loop flexibility and solvent dynamics as determinants for the selective inhibition of cyclin-dependent kinase 4: comparative molecular dynamics simulation studies of CDK2 and CDK4.

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http://www.wikidata.org/entity/Q45125293
Fascaplysin as a specific inhibitor for CDK4: insights from molecular modellingIdentifying allosteric fluctuation transitions between different protein conformational states as applied to Cyclin Dependent Kinase 2.Comparison of human and mouse E-selectin binding to Sialyl-Lewis(x).Functional flexibility of human cyclin-dependent kinase-2 and its evolutionary conservation.Palbociclib can overcome mutations in cyclin dependent kinase 6 that break hydrogen bonds between the drug and the protein.In silico three-dimensional pharmacophores for aiding the discovery of the Pfmrk (Plasmodium cyclin-dependent protein kinases) specific inhibitors for the therapeutic treatment of malaria.Inhibitor Selectivity for Cyclin-Dependent Kinase 7: A Structural, Thermodynamic, and Modelling Study.Molecular dynamics analysis to evaluate docking pose prediction.Role of interactions and volume variation in discriminating active and inactive forms of cyclin-dependent kinase-2 inhibitor complexes.Exploring the selectivity of a ligand complex with CDK2/CDK1: a molecular dynamics simulation approach.Cell-cycle regulators are involved in transient cerebral ischemia induced neuronal apoptosis in female rats.Role of phosphorylated Thr160 for the activation of the CDK2/Cyclin A complex.Molecular modeling studies to characterize N-phenylpyrimidin-2-amine selectivity for CDK2 and CDK4 through 3D-QSAR and molecular dynamics simulations.
P2860

Loop flexibility and solvent dynamics as determinants for the selective inhibition of cyclin-dependent kinase 4: comparative molecular dynamics simulation studies of CDK2 and CDK4.

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http://www.wikidata.org/entity/Q45125293
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年学术文章
@wuu
2004年学术文章
@zh
2004年学术文章
@zh-cn
2004年学术文章
@zh-hans
2004年学术文章
@zh-my
2004年学术文章
@zh-sg
2004年學術文章
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2004年學術文章
@zh-hant
name
Loop flexibility and solvent d ...... tion studies of CDK2 and CDK4.
@en
Loop flexibility and solvent d ...... tion studies of CDK2 and CDK4.
@nl
type
label
Loop flexibility and solvent d ...... tion studies of CDK2 and CDK4.
@en
Loop flexibility and solvent d ...... tion studies of CDK2 and CDK4.
@nl
prefLabel
Loop flexibility and solvent d ...... tion studies of CDK2 and CDK4.
@en
Loop flexibility and solvent d ...... tion studies of CDK2 and CDK4.
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P433
P478
P577
P698
P356
P1433
P1476
Loop flexibility and solvent d ...... tion studies of CDK2 and CDK4.
@en
P2093
P2860
P304
P31
P356
P433
P478
P577
P698