Loop flexibility and solvent dynamics as determinants for the selective inhibition of cyclin-dependent kinase 4: comparative molecular dynamics simulation studies of CDK2 and CDK4.
about
Fascaplysin as a specific inhibitor for CDK4: insights from molecular modellingIdentifying allosteric fluctuation transitions between different protein conformational states as applied to Cyclin Dependent Kinase 2.Comparison of human and mouse E-selectin binding to Sialyl-Lewis(x).Functional flexibility of human cyclin-dependent kinase-2 and its evolutionary conservation.Palbociclib can overcome mutations in cyclin dependent kinase 6 that break hydrogen bonds between the drug and the protein.In silico three-dimensional pharmacophores for aiding the discovery of the Pfmrk (Plasmodium cyclin-dependent protein kinases) specific inhibitors for the therapeutic treatment of malaria.Inhibitor Selectivity for Cyclin-Dependent Kinase 7: A Structural, Thermodynamic, and Modelling Study.Molecular dynamics analysis to evaluate docking pose prediction.Role of interactions and volume variation in discriminating active and inactive forms of cyclin-dependent kinase-2 inhibitor complexes.Exploring the selectivity of a ligand complex with CDK2/CDK1: a molecular dynamics simulation approach.Cell-cycle regulators are involved in transient cerebral ischemia induced neuronal apoptosis in female rats.Role of phosphorylated Thr160 for the activation of the CDK2/Cyclin A complex.Molecular modeling studies to characterize N-phenylpyrimidin-2-amine selectivity for CDK2 and CDK4 through 3D-QSAR and molecular dynamics simulations.
P2860
Q28482234-E114DEEA-E7E1-4FA6-8D81-2D9BD09D989BQ33272661-2B6FDE8F-368A-43DB-B405-BB27BE6D4951Q36066192-C323D277-96BB-4C80-8DD3-22893E055371Q36281964-36217C2D-BA9D-43F6-9809-20A627E3BD2CQ37723172-5F802839-56C8-4EE8-A45C-71692D25BF10Q38088782-42C2A440-DF91-46BB-8E09-8A7B8A149A38Q38997714-5650BA5A-B51D-4C09-8005-A406732D3595Q41227055-7868F4BE-C613-49A1-ADA5-669D779326D6Q43891873-C4176144-FF54-48C5-976B-192608709A34Q45922261-960AD269-A00F-4E82-92D9-A0B8FA50D519Q46648732-A3E93026-745E-43B3-B9C5-5EB9523CFD48Q46808448-669F5EEA-E8FD-4729-8C86-51F8220E3FEFQ50711550-069FDFF3-BC98-46D2-90B4-83DFE78A4498
P2860
Loop flexibility and solvent dynamics as determinants for the selective inhibition of cyclin-dependent kinase 4: comparative molecular dynamics simulation studies of CDK2 and CDK4.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年学术文章
@wuu
2004年学术文章
@zh
2004年学术文章
@zh-cn
2004年学术文章
@zh-hans
2004年学术文章
@zh-my
2004年学术文章
@zh-sg
2004年學術文章
@yue
2004年學術文章
@zh-hant
name
Loop flexibility and solvent d ...... tion studies of CDK2 and CDK4.
@en
Loop flexibility and solvent d ...... tion studies of CDK2 and CDK4.
@nl
type
label
Loop flexibility and solvent d ...... tion studies of CDK2 and CDK4.
@en
Loop flexibility and solvent d ...... tion studies of CDK2 and CDK4.
@nl
prefLabel
Loop flexibility and solvent d ...... tion studies of CDK2 and CDK4.
@en
Loop flexibility and solvent d ...... tion studies of CDK2 and CDK4.
@nl
P2093
P2860
P356
P1433
P1476
Loop flexibility and solvent d ...... tion studies of CDK2 and CDK4.
@en
P2093
Hwangseo Park
Min Sun Yeom
Sangyoub Lee
P2860
P304
P356
10.1002/CBIC.200400214
P577
2004-12-01T00:00:00Z