The mast cell-restricted tryptase mMCP-6 has a critical immunoprotective role in bacterial infections. - Wikidata - awgldk - TriplyDB

The mast cell-restricted tryptase mMCP-6 has a critical immunoprotective role in bacterial infections.

The mast cell-restricted tryptase mMCP-6 has a critical immunoprotective role in bacterial infections.

http://www.wikidata.org/entity/Q45134515

about

Mas-related gene X2 (MrgX2) is a novel G protein-coupled receptor for the antimicrobial peptide LL-37 in human mast cells: resistance to receptor phosphorylation, desensitization, and internalization New developments in mast cell biology Human subjects are protected from mast cell tryptase deficiency despite frequent inheritance of loss-of-function mutations New era for mucosal mast cells: their roles in inflammation, allergic immune responses and adjuvant development The multifaceted mast cell in inflammatory bowel disease Roles of Mas-related G protein-coupled receptor X2 on mast cell-mediated host defense, pseudoallergic drug reactions, and chronic inflammatory diseases Nuclear receptor 4a3 (nr4a3) regulates murine mast cell responses and granule content Munc18b is an essential gene in mice whose expression is limiting for secretion by airway epithelial and mast cells Mast cells and influenza a virus: association with allergic responses and beyond.Essential role for mast cell tryptase in acute experimental colitis Opportunistic pathogen Candida albicans elicits a temporal response in primary human mast cells.Infection of mast cells with live streptococci causes a toll-like receptor 2- and cell-cell contact-dependent cytokine and chemokine response Mast cell-derived TNF can exacerbate mortality during severe bacterial infections in C57BL/6-KitW-sh/W-sh mice.Transcription factor GATA1 is dispensable for mast cell differentiation in adult mice Mast cell and T cell communication; amplification and control of adaptive immunity Mast cell peptidases: chameleons of innate immunity and host defense.Biological implications of preformed mast cell mediators.A new short-term mouse model of chronic obstructive pulmonary disease identifies a role for mast cell tryptase in pathogenesis.Immunomodulatory mast cells: negative, as well as positive, regulators of immunity Neurotensin increases mortality and mast cells reduce neurotensin levels in a mouse model of sepsis.Synovial fibroblasts promote the expression and granule accumulation of tryptase via interleukin-33 and its receptor ST-2 (IL1RL1)Development of mast cells and importance of their tryptase and chymase serine proteases in inflammation and wound healing.Importance of mast cell Prss31/transmembrane tryptase/tryptase-γ in lung function and experimental chronic obstructive pulmonary disease and colitis Parasitic infection improves survival from septic peritonitis by enhancing mast cell responses to bacteria in mice.Ancient origin of mast cells.Allergic airway inflammation decreases lung bacterial burden following acute Klebsiella pneumoniae infection in a neutrophil- and CCL8-dependent manner.Serglycin-independent release of active mast cell proteases in response to Toxoplasma gondii infection.Mast cell function: a new vision of an old cell.Interleukin-33 primes mast cells for activation by IgG immune complexes Mast cell proteases as pharmacological targets The inflammatory response after an epidermal burn depends on the activities of mouse mast cell proteases 4 and 5.Mast cell tryptase deficiency attenuates mouse abdominal aortic aneurysm formation Protease phenotype of constitutive connective tissue and of induced mucosal mast cells in mice is regulated by the tissue.Mast cell secretory granules: armed for battle.Anaplasma phagocytophilum infects mast cells via alpha1,3-fucosylated but not sialylated glycans and inhibits IgE-mediated cytokine production and histamine release.Mast cell-orchestrated immunity to pathogens.Mast cells mediate acute kidney injury through the production of TNF.Plasticity in mast cell responses during bacterial infections.Mast cell restricted mouse and human tryptase·heparin complexes hinder thrombin-induced coagulation of plasma and the generation of fibrin by proteolytically destroying fibrinogen Phenotypic and functional plasticity of cells of innate immunity: macrophages, mast cells and neutrophils.

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P2860

The mast cell-restricted tryptase mMCP-6 has a critical immunoprotective role in bacterial infections.

http://www.wikidata.org/entity/Q45134515

description

2007 nî lūn-bûn

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2007年の論文

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2007年学术文章

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2007年学术文章

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2007年學術文章

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name

The mast cell-restricted trypt ...... role in bacterial infections.

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The mast cell-restricted trypt ...... role in bacterial infections.

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The mast cell-restricted trypt ...... role in bacterial infections.

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The mast cell-restricted trypt ...... role in bacterial infections.

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The mast cell-restricted trypt ...... role in bacterial infections.

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The mast cell-restricted trypt ...... role in bacterial infections.

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Journal of Biological Chemistry

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The mast cell-restricted trypt ...... role in bacterial infections.

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P2093

Leticia Sansores-Garcia

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Richard L Stevens

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Shakeel M Thakurdas

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Youlia Petrova

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P2860

Cloning and characterization of a second complementary DNA for human tryptase

Human mast cell tryptase: multiple cDNAs and genes reveal a multigene serine protease family

Human beta-tryptase is a ring-like tetramer with active sites facing a central pore

Heparin is essential for the storage of specific granule proteases in mast cells

Mouse chromosome 17A3.3 contains 13 genes that encode functional tryptic-like serine proteases with distinct tissue and cell expression patterns

Evaluation of the substrate specificity of human mast cell tryptase beta I and demonstration of its importance in bacterial infections of the lung.

Definition of the extended substrate specificity determinants for beta-tryptases I and II.

Isolation, characterization, and transcription of the gene encoding mouse mast cell protease 7

Human Mast cell progenitors can be infected by macrophagetropic human immunodeficiency virus type 1 and retain virus with maturation in vitro.

Biochemical and functional characterization of human transmembrane tryptase (TMT)/tryptase gamma. TMT is an exocytosed mast cell protease that induces airway hyperresponsiveness in vivo via an interleukin-13/interleukin-4 receptor alpha/signal trans

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20809-20815

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10.1074/JBC.M611842200

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29

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282

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Ernestina Melicoff

Daniel C Moreira

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2007-04-23T00:00:00Z

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17456473

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