A mutant form of the rho protein can restore stress fibers and adhesion plaques in v-src transformed fibroblasts.
about
The intrinsic ability of AFAP-110 to alter actin filament integrity is linked with its ability to also activate cellular tyrosine kinases.Active Rho is localized to podosomes induced by oncogenic Src and is required for their assembly and function.Disruption of c-Jun reduces cellular migration and invasion through inhibition of c-Src and hyperactivation of ROCK II kinase.Analysis of the signaling pathways regulating Src-dependent remodeling of the actin cytoskeleton.Smooth muscle α-actin is a direct target of PLZF: effects on the cytoskeleton and on susceptibility to oncogenic transformation.NaLi-H1: A universal synthetic library of humanized nanobodies providing highly functional antibodies and intrabodies.ERK5 promotes Src-induced podosome formation by limiting Rho activation.Effects of constitutively active GTPases on fibroblast behavior.Recurrent mutations in epigenetic regulators, RHOA and FYN kinase in peripheral T cell lymphomasAn unusual antithrombin-binding heparin octasaccharide with an additional 3-O-sulfated glucosamine in the active pentasaccharide sequence.Specific SHP-2 partitioning in raft domains triggers integrin-mediated signaling via Rho activation.Shp-2 mediates v-Src-induced morphological changes and activation of the anti-apoptotic protein kinase Akt.Genomic landscape of cutaneous T cell lymphoma.Oncogenic Ras leads to Rho activation by activating the mitogen-activated protein kinase pathway and decreasing Rho-GTPase-activating protein activity.Differential requirement for Rho family GTPases in an oncogenic insulin-like growth factor-I receptor-induced cell transformation.FAK regulates tyrosine phosphorylation of CAS, paxillin, and PYK2 in cells expressing v-Src, but is not a critical determinant of v-Src transformation.MEK mediates v-Src-induced disruption of the actin cytoskeleton via inactivation of the Rho-ROCK-LIM kinase pathway.STD and TRNOESY NMR studies on the conformation of the oncogenic protein beta-catenin containing the phosphorylated motif DpSGXXpS bound to the beta-TrCP protein.Stable expression of intracellular Notch suppresses v-Src-induced transformation in avian neural cells.
P2860
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P2860
A mutant form of the rho protein can restore stress fibers and adhesion plaques in v-src transformed fibroblasts.
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年学术文章
@wuu
1999年学术文章
@zh
1999年学术文章
@zh-cn
1999年学术文章
@zh-hans
1999年学术文章
@zh-my
1999年学术文章
@zh-sg
1999年學術文章
@yue
1999年學術文章
@zh-hant
name
A mutant form of the rho prote ...... v-src transformed fibroblasts.
@en
A mutant form of the rho prote ...... v-src transformed fibroblasts.
@nl
type
label
A mutant form of the rho prote ...... v-src transformed fibroblasts.
@en
A mutant form of the rho prote ...... v-src transformed fibroblasts.
@nl
prefLabel
A mutant form of the rho prote ...... v-src transformed fibroblasts.
@en
A mutant form of the rho prote ...... v-src transformed fibroblasts.
@nl
P2093
P2860
P356
P1433
P1476
A mutant form of the rho prote ...... v-src transformed fibroblasts.
@en
P2093
P2860
P2888
P304
P356
10.1038/SJ.ONC.1202537
P407
P577
1999-03-01T00:00:00Z
P5875
P6179
1007316383