The ability of Sgs1 to interact with DNA topoisomerase III is essential for damage-induced recombination.
about
Methyl methanesulfonate (MMS) produces heat-labile DNA damage but no detectable in vivo DNA double-strand breaks.Ctf18 is required for homologous recombination-mediated double-strand break repairRmi1, a member of the Sgs1-Top3 complex in budding yeast, contributes to sister chromatid cohesionDpb11, the budding yeast homolog of TopBP1, functions with the checkpoint clamp in recombination repairYeast Rmi1/Nce4 controls genome stability as a subunit of the Sgs1-Top3 complex.Role of Elg1 protein in double strand break repair.RAD50 is required for efficient initiation of resection and recombinational repair at random, gamma-induced double-strand break endsBoth RAD5-dependent and independent pathways are involved in DNA damage-associated sister chromatid exchange in budding yeast.More forks on the road to replication stress recoveryHolliday junction-containing DNA structures persist in cells lacking Sgs1 or Top3 following exposure to DNA damage.Epistasis analysis between homologous recombination genes in Saccharomyces cerevisiae identifies multiple repair pathways for Sgs1, Mus81-Mms4 and RNase H2Ku stabilizes replication forks in the absence of Brc1.Longevity mutation in SCH9 prevents recombination errors and premature genomic instability in a Werner/Bloom model system.A Delicate Balance Between Repair and Replication Factors Regulates Recombination Between Divergent DNA Sequences in Saccharomyces cerevisiaeTop3 processes recombination intermediates and modulates checkpoint activity after DNA damage.Combination of pentafluorophenylhydrazine derivatization and isotope dilution LC-MS/MS techniques for the quantification of apurinic/apyrimidinic sites in cellular DNA.Slx4 becomes phosphorylated after DNA damage in a Mec1/Tel1-dependent manner and is required for repair of DNA alkylation damageTelomerase-associated protein 1, HSP90, and topoisomerase IIalpha associate directly with the BLM helicase in immortalized cells using ALT and modulate its helicase activity using telomeric DNA substrates.Phosphorylation of Slx4 by Mec1 and Tel1 regulates the single-strand annealing mode of DNA repair in budding yeast.Sgs1 regulates gene conversion tract lengths and crossovers independently of its helicase activity.Roles of SGS1, MUS81, and RAD51 in the repair of lagging-strand replication defects in Saccharomyces cerevisiae.The genetic consequences of ablating helicase activity and the Top3 interaction domain of Sgs1.Caenorhabditis elegans BUB-3 and SAN-1/MAD3 Spindle Assembly Checkpoint Components Are Required for Genome Stability in Response to Treatment with Ionizing Radiation.Sgs1 Binding to Rad51 Stimulates Homology-Directed DNA Repair in Saccharomyces cerevisiae.SUMO E3 ligase Mms21 prevents spontaneous DNA damage induced genome rearrangements.High-throughput creation and functional profiling of DNA sequence variant libraries using CRISPR-Cas9 in yeast
P2860
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P2860
The ability of Sgs1 to interact with DNA topoisomerase III is essential for damage-induced recombination.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
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2005年學術文章
@zh-hant
name
The ability of Sgs1 to interac ...... damage-induced recombination.
@en
The ability of Sgs1 to interac ...... damage-induced recombination.
@nl
type
label
The ability of Sgs1 to interac ...... damage-induced recombination.
@en
The ability of Sgs1 to interac ...... damage-induced recombination.
@nl
prefLabel
The ability of Sgs1 to interac ...... damage-induced recombination.
@en
The ability of Sgs1 to interac ...... damage-induced recombination.
@nl
P2093
P1433
P1476
The ability of Sgs1 to interac ...... damage-induced recombination.
@en
P2093
Fumitoshi Onoda
Hideaki Ogiwara
Masayuki Seki
Ryoko Onodera
Shin-ichi Fukushige
Takemi Enomoto
P304
P356
10.1016/J.DNAREP.2004.09.002
P577
2005-02-01T00:00:00Z