Insulin resistance in human adipocytes occurs downstream of IRS1 after surgical cell isolation but at the level of phosphorylation of IRS1 in type 2 diabetes.
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ZnO Nanostructure-Based Intracellular SensorHistone variants and their post-translational modifications in primary human fat cellsPhosphorylation of IRS1 at serine 307 in response to insulin in human adipocytes is not likely to be catalyzed by p70 ribosomal S6 kinaseA hierarchical whole-body modeling approach elucidates the link between in Vitro insulin signaling and in Vivo glucose homeostasis.Combining Hi-C data with phylogenetic correlation to predict the target genes of distal regulatory elements in human genome.Model-based hypothesis testing of key mechanisms in initial phase of insulin signaling.Attenuated mTOR signaling and enhanced autophagy in adipocytes from obese patients with type 2 diabetesDifferential regulation of adipocyte PDE3B in distinct membrane compartments by insulin and the beta3-adrenergic receptor agonist CL316243: effects of caveolin-1 knockdown on formation/maintenance of macromolecular signalling complexes.Increased adipogenesis of human adipose-derived stem cells on polycaprolactone fiber matrices.A single mechanism can explain network-wide insulin resistance in adipocytes from obese patients with type 2 diabetes.Deletion of the androgen receptor in adipose tissue in male mice elevates retinol binding protein 4 and reveals independent effects on visceral fat mass and on glucose homeostasis.Insulin signaling in type 2 diabetes: experimental and modeling analyses reveal mechanisms of insulin resistance in human adipocytes.Systems-wide Experimental and Modeling Analysis of Insulin Signaling through Forkhead Box Protein O1 (FOXO1) in Human Adipocytes, Normally and in Type 2 Diabetes.Global differences in specific histone H3 methylation are associated with overweight and type 2 diabetes.A new mathematical approach for qualitative modeling of the insulin-TOR-MAPK network.Postreceptoral adipocyte insulin resistance induced by nelfinavir is caused by insensitivity of PKB/Akt to phosphatidylinositol-3,4,5-trisphosphate.Short-term overeating induces insulin resistance in fat cells in lean human subjects.The concentration of β-carotene in human adipocytes, but not the whole-body adipocyte stores, is reduced in obesity.Hepatic Expression of Adenovirus 36 E4ORF1 Improves Glycemic Control and Promotes Glucose Metabolism Through AKT Activation.Mass and information feedbacks through receptor endocytosis govern insulin signaling as revealed using a parameter-free modeling framework.Zinc Oxide-Based Self-Powered Potentiometric Chemical Sensors for Biomolecules and Metal Ions.Receptor and post-receptor abnormalities contribute to insulin resistance in myotonic dystrophy type 1 and type 2 skeletal muscle.Growth and Structure of ZnO Nanorods on a Sub-Micrometer Glass Pipette and Their Application as Intracellular Potentiometric Selective Ion Sensors.Interaction between serine phosphorylated IRS-1 and beta1-integrin affects the stability of neuronal processesAttenuation of insulin-stimulated insulin receptor substrate-1 serine 307 phosphorylation in insulin resistance of type 2 diabetes.Extracts from Plastrum testudinis promote proliferation of rat bone-marrow-derived mesenchymal stem cells.
P2860
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P2860
Insulin resistance in human adipocytes occurs downstream of IRS1 after surgical cell isolation but at the level of phosphorylation of IRS1 in type 2 diabetes.
description
2005 nî lūn-bûn
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2005年の論文
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2005年学术文章
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2005年学术文章
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2005年学术文章
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2005年学术文章
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2005年学术文章
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2005年学术文章
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2005年學術文章
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2005年學術文章
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name
Insulin resistance in human ad ...... on of IRS1 in type 2 diabetes.
@en
Insulin resistance in human ad ...... on of IRS1 in type 2 diabetes.
@nl
type
label
Insulin resistance in human ad ...... on of IRS1 in type 2 diabetes.
@en
Insulin resistance in human ad ...... on of IRS1 in type 2 diabetes.
@nl
prefLabel
Insulin resistance in human ad ...... on of IRS1 in type 2 diabetes.
@en
Insulin resistance in human ad ...... on of IRS1 in type 2 diabetes.
@nl
P2093
P921
P1433
P1476
Insulin resistance in human ad ...... ion of IRS1 in type 2 diabetes
@en
P2093
Anna Danielsson
Erika Lystedt
Johanna Gustavsson
Preben Kjolhede
P2860
P304
P356
10.1111/J.1432-1033.2004.04396.X
P407
P577
2005-01-01T00:00:00Z