Activation of group II mGlu receptors blocks the enhanced drug taking induced by previous exposure to amphetamine.
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The mGluR2 positive allosteric modulator BINA decreases cocaine self-administration and cue-induced cocaine-seeking and counteracts cocaine-induced enhancement of brain reward function in ratsGlutamatergic substrates of drug addiction and alcoholismPresynaptic G Protein-Coupled Receptors: Gatekeepers of Addiction?Metabotropic glutamate receptor 3 is associated with heroin dependence but not depression or schizophrenia in a Chinese populationAllosteric modulation of metabotropic glutamate receptors.Previous exposure to delta9-tetrahydrocannibinol enhances locomotor responding to but not self-administration of amphetamine.Place preference induced by nucleus accumbens amphetamine is impaired by local blockade of Group II metabotropic glutamate receptors in rats.Cocaine-induced neuroadaptations in glutamate transmission: potential therapeutic targets for craving and addictionTransient overexpression of alpha-Ca2+/calmodulin-dependent protein kinase II in the nucleus accumbens shell enhances behavioral responding to amphetamine.The effects of mGluR2/3 activation on acute and repeated amphetamine-induced locomotor activity in differentially reared male ratsEffects of the mGlu2/3 agonist LY379268 and the mGlu5 antagonist MTEP on ethanol seeking and reinforcement are differentially altered in rats with a history of ethanol dependenceImpact of metabotropic glutamate 2/3 receptor stimulation on activated dopamine release and locomotionAMPA receptor plasticity in the nucleus accumbens after repeated exposure to cocaine.Striatal ups and downs: their roles in vulnerability to addictions in humansThe preclinical properties of a novel group II metabotropic glutamate receptor agonist LY379268.Drug wanting: behavioral sensitization and relapse to drug-seeking behaviorActivation of group II metabotropic glutamate receptors in the nucleus accumbens shell attenuates context-induced relapse to heroin seeking.Role of the prefrontal cortex and nucleus accumbens in reinstating methamphetamine seekingGroup II metabotropic glutamate receptors (mGlu2/3) in drug addiction.The metabotropic glutamate 2/3 receptor agonist LY379268 blocked nicotine-induced increases in nucleus accumbens shell dopamine only in the presence of a nicotine-associated context in rats.The dopamine D1-D2 receptor heteromer exerts a tonic inhibitory effect on the expression of amphetamine-induced locomotor sensitization.Glutamate transmission in addiction.α-1 Adrenergic receptors are localized on presynaptic elements in the nucleus accumbens and regulate mesolimbic dopamine transmission.Attenuation of methamphetamine seeking by the mGluR2/3 agonist LY379268 in rats with histories of restricted and escalated self-administration.Hypothesis-driven medication discovery for the treatment of psychostimulant addictionThe group II metabotropic glutamate receptor agonist, LY379268, decreases methamphetamine self-administration in rats.Amphetamine-induced changes in dendritic morphology in rat forebrain correspond to associative drug conditioning rather than nonassociative drug sensitization.Interactions between the mGluR2/3 agonist, LY379268, and cocaine on in vivo neurochemistry and behavior in squirrel monkeys.Calcium-dependent networks in dopamine-glutamate interaction: the role of postsynaptic scaffolding proteins.Cocaine self-administration reduces excitatory responses in the mouse nucleus accumbens shell.Sensitizing exposure to amphetamine increases AMPA receptor phosphorylation without increasing cell surface expression in the rat nucleus accumbens.
P2860
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P2860
Activation of group II mGlu receptors blocks the enhanced drug taking induced by previous exposure to amphetamine.
description
2005 nî lūn-bûn
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2005年の論文
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2005年学术文章
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2005年学术文章
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name
Activation of group II mGlu re ...... vious exposure to amphetamine.
@en
Activation of group II mGlu re ...... vious exposure to amphetamine.
@nl
type
label
Activation of group II mGlu re ...... vious exposure to amphetamine.
@en
Activation of group II mGlu re ...... vious exposure to amphetamine.
@nl
prefLabel
Activation of group II mGlu re ...... vious exposure to amphetamine.
@en
Activation of group II mGlu re ...... vious exposure to amphetamine.
@nl
P2093
P1476
Activation of group II mGlu re ...... evious exposure to amphetamine
@en
P2093
Elizabeth Creekmore
Jennifer D Austin
Paul Vezina
P304
P356
10.1111/J.1460-9568.2004.03822.X
P407
P577
2005-01-01T00:00:00Z