Aminoimidazolylmethyluracil analogues as potent inhibitors of thymidine phosphorylase and their bioreductive nitroimidazolyl prodrugs.
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Preferential inhibition of xanthine oxidase by 2-amino-6-hydroxy-8-mercaptopurine and 2-amino-6-purine thiolNew Frontiers in DruggabilityA kinetic, modeling and mechanistic re-analysis of thymidine phosphorylase and some related enzymes.Antiangiogenic and antitumor activity of 6-(2-aminoethyl)amino-5-chlorouracil, a novel small-molecule inhibitor of thymidine phosphorylase, in combination with the vascular endothelial growth factor-trap.Use of machine learning approaches for novel drug discovery.Recent advances in targeting the fatty acid biosynthetic pathway using fatty acid synthase inhibitors.Hepatocellular carcinoma targeting agents: conjugates of nitroimidazoles with trimethyl nordihydroguaiaretic acid.The formation of thymidine-based T-tetramers with remarkable structural and metal ion size effects.Design, synthesis and enzymatic evaluation of 6-bridged imidazolyluracil derivatives as inhibitors of human thymidine phosphorylase.
P2860
Q33285055-F4709469-DE94-4EA0-940D-5CA5B49C8B83Q35730955-F688005C-2336-4705-8347-C68AA0515EC3Q36694517-2FE2719A-94A3-49B5-B1F4-B195C1D72E84Q37421793-5C9573A6-CB17-4D88-999A-438AE1ABFD9FQ38712793-32821B7B-C489-4AB6-AB20-E234427E792DQ38972039-C25C5EA1-A07D-4638-8945-8A2A67467FBCQ39013727-66FAF4A9-F935-4A8A-96CE-E5429A25C923Q47400547-4712928F-36B6-4FD4-B100-DF3CC30F93C3Q53742004-7AA59F3E-465E-4318-BCF3-AA3394E0D9D7
P2860
Aminoimidazolylmethyluracil analogues as potent inhibitors of thymidine phosphorylase and their bioreductive nitroimidazolyl prodrugs.
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2005 nî lūn-bûn
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2005年の論文
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name
Aminoimidazolylmethyluracil an ...... tive nitroimidazolyl prodrugs.
@en
Aminoimidazolylmethyluracil an ...... tive nitroimidazolyl prodrugs.
@nl
type
label
Aminoimidazolylmethyluracil an ...... tive nitroimidazolyl prodrugs.
@en
Aminoimidazolylmethyluracil an ...... tive nitroimidazolyl prodrugs.
@nl
prefLabel
Aminoimidazolylmethyluracil an ...... tive nitroimidazolyl prodrugs.
@en
Aminoimidazolylmethyluracil an ...... tive nitroimidazolyl prodrugs.
@nl
P2093
P50
P356
P1476
Aminoimidazolylmethyluracil an ...... ctive nitroimidazolyl prodrugs
@en
P2093
Abdul Gbaj
Ken M Page
Kenneth T Douglas
Mohammed Jaffar
Philip N Edwards
Philip Reigan
Richard W A Luke
Simon T Barry
Susan E Ashton
P304
P356
10.1021/JM049494R
P407
P577
2005-01-01T00:00:00Z