Long-term preservation of retinal function in the RCS rat model of retinitis pigmentosa following lentivirus-mediated gene therapy.
about
Lentiviral gene transfer of RPE65 rescues survival and function of cones in a mouse model of Leber congenital amaurosisRegulation of PCNA and cyclin D1 expression and epithelial morphogenesis by the ZO-1-regulated transcription factor ZONAB/DbpAUsing magnetic resonance imaging to assess visual deficits: a reviewAAV-mediated gene therapy in mouse models of recessive retinal degenerationA comprehensive review of retinal gene therapyTransplantation of rat embryonic stem cell-derived retinal progenitor cells preserves the retinal structure and function in rat retinal degeneration.Retinal degeneration progression changes lentiviral vector cell targeting in the retinaPhagocytic clearance in neurodegeneration.Dynamic clonal analysis of murine hematopoietic stem and progenitor cells marked by 5 fluorescent proteins using confocal and multiphoton microscopy.Lentiviral-vector-mediated expression of murine IL-1 receptor antagonist or IL-10 reduces the severity of endotoxin-induced uveitisLentivirus-mediated RNA interference of vascular endothelial growth factor in monkey eyes with iris neovascularization.The tight junction associated signalling proteins ZO-1 and ZONAB regulate retinal pigment epithelium homeostasis in mice.Targeted disruption of outer limiting membrane junctional proteins (Crb1 and ZO-1) increases integration of transplanted photoreceptor precursors into the adult wild-type and degenerating retina.Regulation of phagocytosis by TAM receptors and their ligands.Reduction of choroidal neovascularization in mice by adeno-associated virus-delivered anti-vascular endothelial growth factor short hairpin RNA.Understanding lentiviral vector chromatin targeting: working to reduce insertional mutagenic potential for gene therapy.Effective gene therapy with nonintegrating lentiviral vectors.Vector platforms for gene therapy of inherited retinopathies.Lentiviral gene replacement therapy of retinas in a mouse model for Usher syndrome type 1B.TAM receptor tyrosine kinases: biologic functions, signaling, and potential therapeutic targeting in human cancer.AAV and compacted DNA nanoparticles for the treatment of retinal disorders: challenges and future prospects.A novel MERTK deletion is a common founder mutation in the Faroe Islands and is responsible for a high proportion of retinitis pigmentosa casesClinical characteristics and current therapies for inherited retinal degenerationsGene therapy for ocular diseasesRepublished review: Gene therapy for ocular diseases.Stem cells as tools in regenerative therapy for retinal degeneration.C1q enhances cone photoreceptor survival in a mouse model of autosomal recessive retinitis pigmentosa.Clinical characterisation of a family with retinal dystrophy caused by mutation in the Mertk geneTargeted transgene expression in muller glia of normal and diseased retinas using lentiviral vectors.Gene therapy of inherited retinopathies: a long and successful road from viral vectors to patients.Nanoparticle-motivated gene delivery for ophthalmic applicationGene therapy progress and prospects: the eye.Pharmacological disruption of the outer limiting membrane leads to increased retinal integration of transplanted photoreceptor precursors.Nanoparticle applications in ocular gene therapyBarriers for retinal gene therapy: separating fact from fiction.A review of in vivo animal studies in retinal prosthesis research.Nonviral ocular gene therapy: assessment and future directions.Gene therapy for retinitis pigmentosa and Leber congenital amaurosis caused by defects in AIPL1: effective rescue of mouse models of partial and complete Aipl1 deficiency using AAV2/2 and AAV2/8 vectorsPhotoreceptor precursors derived from three-dimensional embryonic stem cell cultures integrate and mature within adult degenerate retina.Preclinical potency and safety studies of an AAV2-mediated gene therapy vector for the treatment of MERTK associated retinitis pigmentosa.
P2860
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P2860
Long-term preservation of retinal function in the RCS rat model of retinitis pigmentosa following lentivirus-mediated gene therapy.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
@zh-hant
name
Long-term preservation of reti ...... tivirus-mediated gene therapy.
@en
Long-term preservation of reti ...... tivirus-mediated gene therapy.
@nl
type
label
Long-term preservation of reti ...... tivirus-mediated gene therapy.
@en
Long-term preservation of reti ...... tivirus-mediated gene therapy.
@nl
prefLabel
Long-term preservation of reti ...... tivirus-mediated gene therapy.
@en
Long-term preservation of reti ...... tivirus-mediated gene therapy.
@nl
P2093
P2860
P356
P1433
P1476
Long-term preservation of reti ...... tivirus-mediated gene therapy.
@en
P2093
Balaggan KS
Schlichtenbrede FC
Thrasher AJ
Tschernutter M
P2860
P2888
P304
P356
10.1038/SJ.GT.3302460
P577
2005-04-01T00:00:00Z
P5875
P6179
1007007348