Beta-amyloid-induced neuronal apoptosis involves c-Jun N-terminal kinase-dependent downregulation of Bcl-w.
about
Signaling effect of amyloid-beta(42) on the processing of AbetaPPc-Jun N-terminal Kinase (JNK) Signaling as a Therapeutic Target for Alzheimer's DiseaseAnti-apoptotic BCL-2 family proteins in acute neural injuryCeramides in Alzheimer's Disease: Key Mediators of Neuronal Apoptosis Induced by Oxidative Stress and Aβ AccumulationThe pro-domains of neurotrophins, including BDNF, are linked to Alzheimer's disease through a toxic synergy with AβThe c-jun kinase/stress-activated pathway: regulation, function and role in human disease.The modular systems biology approach to investigate the control of apoptosis in Alzheimer's disease neurodegeneration.Kihi-to, a herbal traditional medicine, improves Abeta(25-35)-induced memory impairment and losses of neurites and synapses.Nicotinic acetylcholine receptor signalling: roles in Alzheimer's disease and amyloid neuroprotection.Vascular endothelial barrier dysfunction mediated by amyloid-beta proteins.Anti-amyloidogenic and anti-apoptotic role of melatonin in Alzheimer diseaseNeuroprotective effects of garlic a review.Sensory neuropathy attributable to loss of Bcl-w.Salubrinal attenuates β-amyloid-induced neuronal death and microglial activation by inhibition of the NF-κB pathway.MicroRNA-335 acts as a metastasis suppressor in gastric cancer by targeting Bcl-w and specificity protein 1Nicotinic Acetylcholine Receptors Sensitize a MAPK-linked Toxicity Pathway on Prolonged Exposure to β-Amyloid.Genistein protects against Aβ25-35 induced apoptosis of PC12 cells through JNK signaling and modulation of Bcl-2 family messengers.Oxidative stress activates a positive feedback between the gamma- and beta-secretase cleavages of the beta-amyloid precursor proteinBACE1 is at the crossroad of a toxic vicious cycle involving cellular stress and β-amyloid production in Alzheimer's diseaseExploring the contribution of estrogen to amyloid-Beta regulation: a novel multifactorial computational modeling approach.Oxidative stress and the pathogenesis of Alzheimer's disease.JNK-mediated phosphorylation of DLK suppresses its ubiquitination to promote neuronal apoptosis.Distinct spatial activation of intrinsic and extrinsic apoptosis pathways in natural scrapie: association with prion-related lesionsProtective actions of sex steroid hormones in Alzheimer's disease.Differential regulation of Smac/DIABLO and Hsp-70 during brain maturationEpigenome-wide differences in pathology-free regions of multiple sclerosis-affected brains.JNK: a stress-activated protein kinase therapeutic strategies and involvement in Alzheimer's and various neurodegenerative abnormalities.Road to Alzheimer's disease: the pathomechanism underlying.Beta-amyloid oligomers: recent developments.Amyloid beta₁₋₄₂ (Aβ₄₂) up-regulates the expression of sortilin via the p75(NTR)/RhoA signaling pathway.The effect of geniste on Aβ25-35-induced PC12 cell apoptosis through the JNK-dependent Fas pathway.β-amyloid 1-42 induces physiological transcriptional regulation of BACE1.Tauroursodeoxycholic acid modulates p53-mediated apoptosis in Alzheimer's disease mutant neuroblastoma cells.Insulin deficiency exacerbates cerebral amyloidosis and behavioral deficits in an Alzheimer transgenic mouse model.Arrestins in apoptosis.Exendin-4, a glucagon-like peptide-1 receptor agonist, inhibits Aβ25-35-induced apoptosis in PC12 cells by suppressing the expression of endoplasmic reticulum stress-related proteins.Neuron specific toxicity of oligomeric amyloid-β: role for JUN-kinase and oxidative stress.Cloning and characterization of the 5'UTR of the rat anti-apoptotic Bcl-w gene.Differential modulation of Alzheimer's disease amyloid beta-peptide accumulation by diverse classes of metal ligands.Up-regulation of Bcl-2 in APP transgenic mice is associated with neuroprotection.
P2860
Q24656147-3D12FB36-9A5E-401A-858F-B579FC7E727EQ26770431-ED5061EF-CC33-4FF3-8B61-E90528ADA0F3Q26862539-EE8357FC-B286-4494-BAD4-9FB61C1B0E32Q28087030-A0EDF216-C2D8-4781-8A5B-1AFEFB09EC3DQ30374487-C8FA9422-E54C-4BAD-BFFE-10617230BC62Q30500831-9624311E-6338-4A8C-83A7-16D9F9094A85Q33264215-4F07F514-06DE-46CF-884B-2839D1A72E4EQ33360444-096A5C1C-F0C0-4874-B300-394188596AEBQ33694502-10D86F5E-2410-4D9D-B730-1F7BB7089A06Q33780717-BBCCBBCD-7D54-40C2-BA42-4AF60DC7932AQ34402167-4C432C44-9275-4E36-BB3F-9E0213318A4CQ34780386-DC8A6416-285B-4798-AC91-A45B84DA327EQ34780573-1F7F1BDC-4819-49A5-9D05-DD2B8B3F3BDBQ35803982-571E5F85-96FD-442E-85DF-D99883C72CF1Q35853031-92632B35-A1B6-41A7-A190-0C23C2926B29Q36065073-BFDB1ABB-55DE-46A4-A54A-E50BD187DCD2Q36248069-CC351844-5786-473F-AC81-C7B3529F9802Q36417576-1C849DF1-5A35-4F54-BB71-9702FE01B135Q36427048-2400799F-5C26-4000-9FCA-B0132FDBC32BQ36648823-7DB5EC2F-AD30-41B8-8015-4D2A3F408666Q37101305-2F96F483-EA39-4859-BF44-1AF5F58681D8Q37141102-072A3C5A-E700-4968-B843-774023758652Q37239395-6DC72CCB-487B-4735-96BD-D76B43622803Q37309638-571A62AC-41BA-4561-8A56-5F0B883FEEC9Q37371359-247E8584-25C2-429B-BCA7-035FE71EF786Q37602769-A3949822-5F8B-41CD-932D-06A39938AA6DQ37793978-6CE87BA5-65DE-454B-B52E-EC1A871BE4BBQ37972068-7EF50935-49EC-4B94-92D2-1911A2CB6ADAQ38472553-1108823E-B9E2-4EC8-8BA4-160F0BB0A1CEQ39118749-264011B0-38EF-42A8-919D-FFD4FA407F89Q39234100-767AC953-64B8-40A0-91A7-D63920739B36Q39329429-12E27631-F893-4A96-982C-73A2FCFF4855Q40241292-57AB12B6-8E9D-448F-81EA-CF4CC13C178DQ41722230-722751BC-16FE-44E3-AE9B-C626B514B991Q42089456-50B3B976-5912-460C-8760-77FD787E5490Q42255019-C072C06E-88AF-4474-9163-8F044CA1CCE5Q42262790-6156CBD4-48DE-4DF4-9E22-140239971D9BQ42586992-DB7A8530-1700-4743-9741-71628F875B0AQ42723254-0ECABEBD-7C11-4BBE-8981-E4E5606AB0E7Q42757657-6581D607-25BA-45A7-871A-50B98FDE6EBA
P2860
Beta-amyloid-induced neuronal apoptosis involves c-Jun N-terminal kinase-dependent downregulation of Bcl-w.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
@zh-hant
name
Beta-amyloid-induced neuronal ...... ndent downregulation of Bcl-w.
@en
Beta-amyloid-induced neuronal ...... ndent downregulation of Bcl-w.
@nl
type
label
Beta-amyloid-induced neuronal ...... ndent downregulation of Bcl-w.
@en
Beta-amyloid-induced neuronal ...... ndent downregulation of Bcl-w.
@nl
prefLabel
Beta-amyloid-induced neuronal ...... ndent downregulation of Bcl-w.
@en
Beta-amyloid-induced neuronal ...... ndent downregulation of Bcl-w.
@nl
P2093
P1476
Beta-amyloid-induced neuronal ...... endent downregulation of Bcl-w
@en
P2093
Christian J Pike
Mingzhong Yao
Thuy-Vi V Nguyen
P304
P356
10.1523/JNEUROSCI.4736-04.2005
P407
P577
2005-02-01T00:00:00Z